{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:21:26Z","timestamp":1787016086641,"version":"build-2736575974"},"reference-count":33,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T00:00:00Z","timestamp":1683763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The aim of this study was to determine the effectiveness of meloxicam with or without dipyrone on the welfare of ewes subjected to non\u2010surgical embryo recovery (NSER). Two studies were carried out using 51 multiparous Santa In\u00eas ewes. All animals received a standard oestrous synchronization treatment and a superovulatory protocol. In Study 1, 12 ewes received meloxicam (GM) before cervical transposition (1\u2009mg\u2009kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    , i.v.), repeated 24\u2009h after (1\u2009mg\u2009kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    , i.m.), while the other 10 received a saline solution, remaining as a control group (GC1). In Study 2, ewes were allocated into a group of 15 ewes treated as GM of Study 1 associated with dipyrone (GMD; 50\u2009mg\u2009kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    , i.m.) before cervical transposition, 12\u2009h, and 24\u2009h after, or a control group (GC2) of 14 ewes treated with saline solution. In both studies, heart and respiratory rates (RR), cortisol, glucose, total proteins, albumin and globulins blood concentration were recorded before sedation (BS), after sedation (AS), after cervical transposition, immediately after collection (IAC), and 0.5, 1.5, 3, 6, 12, 24 and 48\u2009h after embryo collection (hAC). In Study 1, RR tended to be greater in GC1 (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u2009.08), serum total proteins and globulins values were lower and serum albumin values were greater in this group than GM (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u2009.003,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u2009.0001, and\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u2009.0001, respectively). In Study 2, treatment of GMD tended to reduce the glycaemia at AS (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u2009.052) and reduced it at 3hAC (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u2009.0001), and 6hAC (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u2009.03). It also tended to reduce cortisol concentrations (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u2009.10). The other variables varied with NSER without interaction with the experimental treatments. In conclusion, in this study condition, NSER in sheep induced transient changes indicative of stress and possibly pain, therefore, affecting animal welfare. The administration of meloxicam was ineffective to reduce those responses, and the association of dipyrone had only slight effects without modifying the main welfare indicative responses in ewes subjected to NSER.\n                  <\/jats:p>","DOI":"10.1111\/rda.14375","type":"journal-article","created":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T01:49:10Z","timestamp":1683510550000},"page":"972-981","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Use of meloxicam with or without dipyrone in non\u2010surgical embryo recovery in hair sheep: Effects on animal welfare"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0747-4826","authenticated-orcid":false,"given":"Ana Clara Sarzedas","family":"Ribeiro","sequence":"first","affiliation":[{"name":"Universidade Federal Fluminense  Niter\u00f3i Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Augusto Ryonosuke","family":"Taira","sequence":"additional","affiliation":[{"name":"Universidade Federal Fluminense  Niter\u00f3i Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa Costa","family":"Santos","sequence":"additional","affiliation":[{"name":"Universidade Federal Fluminense  Niter\u00f3i Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviane Lopes","family":"Brair","sequence":"additional","affiliation":[{"name":"Universidade Federal Fluminense  Niter\u00f3i Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Paula Fassarella","family":"Lopes","sequence":"additional","affiliation":[{"name":"Universidade Federal Fluminense  Niter\u00f3i Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario Felipe Alvarez","family":"Balaro","sequence":"additional","affiliation":[{"name":"Universidade Federal Fluminense  Niter\u00f3i Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4872-1718","authenticated-orcid":false,"given":"Joanna Maria Gon\u00e7alves","family":"Souza\u2010Fabjan","sequence":"additional","affiliation":[{"name":"Universidade Federal Fluminense  Niter\u00f3i Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8028-3984","authenticated-orcid":false,"given":"Jeferson Ferreira","family":"da Fonseca","sequence":"additional","affiliation":[{"name":"Embrapa Caprinos e Ovinos  Coronel Pacheco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4685-2105","authenticated-orcid":false,"given":"Rodolfo","family":"Ungerfeld","sequence":"additional","affiliation":[{"name":"Facultad de Veterinaria Universidad de la Rep\u00fablica  Montevideo Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4027-5562","authenticated-orcid":false,"given":"Felipe Zandonadi","family":"Brand\u00e3o","sequence":"additional","affiliation":[{"name":"Universidade Federal Fluminense  Niter\u00f3i Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1751731118000320"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.12968\/live.2017.22.6.324"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/S141395961999000300006"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.domaniend.2015.07.002"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11250\u2010014\u20100672\u20108"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0093\u2010691X(96)00121\u20105"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2885.1997.00098.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781118999196.ch5"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/avj.12779"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-012373898-1.50005-X"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.domaniend.2022.106751"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/rda.13692"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD18324"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2016.04.025"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smallrumres.2012.08.007"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2019.02.004"},{"key":"e_1_2_10_18_1","first-page":"617","volume-title":"Dukes' physiology of domestic animals","author":"Goff J. 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