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Recipients from commercial farms had their oestrous cycle synchronized with an E2\/P4\u2010based protocol in three experiments (Exp. 1 to 3). In Exp. 1, dairy heifers (<jats:italic>n<\/jats:italic>\u2009=\u200976) and cows (<jats:italic>n<\/jats:italic>\u2009=\u2009104) were randomly assigned to two experimental groups: the control group (<jats:italic>n<\/jats:italic>\u2009=\u200989) and the iP4D4 group (<jats:italic>n<\/jats:italic>\u2009=\u200991). For Exps. 2 and 3, suckled beef recipients were used. In Exp. 2, recipients were assigned to two experimental groups: Control group (<jats:italic>n<\/jats:italic>\u2009=\u2009147) and iP4D7 group (<jats:italic>n<\/jats:italic>\u2009=\u2009144); whereas in Exp. 3, recipients were randomly assigned to three experimental groups: Control group (<jats:italic>n<\/jats:italic>\u2009=\u200985), iP4\u2010D4 group (<jats:italic>n<\/jats:italic>\u2009=\u200986) and iP4D7 group (<jats:italic>n<\/jats:italic>\u2009=\u200981). Recipients in the iP4D4 and iP4\u2010D7 groups received an i.m. administration of 150\u2009mg iP4, on D4 or D7 (D0 was the day of expected oestrus). On D7, all recipients were evaluated by transrectal ultrasonography and those that had a CL received a fresh or vitrified in\u00a0vitro<jats:italic>\u2010produced<\/jats:italic>embryo. In Exp. 2 and 3, the CL area was also determined by ultrasonography at the time of FTET. The pregnancy diagnosis was performed at 30\u2009days in Exp. 1, 57\u2009days in Exp. 2, and between 40 and 72\u2009days of pregnancy in Exp. 3. In Exp. 1, the pregnancy rate did not differ (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.1) between the Control group (38.2% [34\/89]) and iP4D4 group (49.5% [45\/91]); yet, a parity effect indicated a greater (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05) pregnancy rate in heifers (57.9% [44\/76]) than cows (30.8% [32\/104]). In Exp. 2, the pregnancy rate was greater (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05) in the iP4D7 group (45.0% [65\/144]) than in the Control group (34.0% [50\/147]). Also, a greater (<jats:italic>p<\/jats:italic>\u2009=\u2009.08) pregnancy rate was observed for recipients with a small CL (\u22642.75\u2009cm<jats:sup>2<\/jats:sup>) that were treated with iP4 on the day of FTET than the control recipients (46.4% [32\/69] vs. 32.6% [28\/86]). In Exp. 3, no significant effects (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.1) of the treatment group or CL size were detected on pregnancy rates at days 30 and 60. In conclusion, the beneficial effects of iP4 supplementation at early dioestrus on pregnancy maintenance may vary according to the experimental conditions, but its use at the time of FTET can be used as an alternative to enhance the fertility of beef recipients in challenging conditions in commercial herds.<\/jats:p>","DOI":"10.1111\/rda.14509","type":"journal-article","created":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T08:54:00Z","timestamp":1701420840000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of long\u2010acting injectable progesterone supplementation at early dioestrus on pregnancy maintenance in beef and dairy recipient cattle"],"prefix":"10.1111","volume":"59","author":[{"given":"Adomar Laurindo","family":"Neto","sequence":"first","affiliation":[{"name":"Department of Animal Reproduction, School of Veterinary Medicine and Animal Science University of S\u00e3o Paulo Pirassununga S\u00e3o Paulo Brazil"},{"name":"Federal University of Esp\u00edrito Santo Vit\u00f3ria Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe Lopes","family":"Ruas","sequence":"additional","affiliation":[{"name":"Federal University of Esp\u00edrito Santo Vit\u00f3ria Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno Silva Esp\u00edrito","family":"Santo","sequence":"additional","affiliation":[{"name":"Federal University of Mato Grosso Cuiab\u00e1 Mato Grosso Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6130-8688","authenticated-orcid":false,"given":"Ana Clara Degan","family":"Mattos","sequence":"additional","affiliation":[{"name":"Department of Animal Reproduction, School of Veterinary Medicine and Animal Science University of S\u00e3o Paulo Pirassununga S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fanior Borges","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Animal Reproduction, School of Veterinary Medicine and Animal Science University of S\u00e3o Paulo Pirassununga S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos Fl\u00e1vio Diniz","family":"J\u00fanior","sequence":"additional","affiliation":[{"name":"Federal University of Mato Grosso Cuiab\u00e1 Mato Grosso Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danilo Fonseca Cardoso","family":"Pereira","sequence":"additional","affiliation":[{"name":"Federal University of Mato Grosso Cuiab\u00e1 Mato Grosso Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izabelle Pereira","family":"Lacerda","sequence":"additional","affiliation":[{"name":"Federal University of Esp\u00edrito Santo Vit\u00f3ria Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Oliveira","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Federal University of Esp\u00edrito Santo Vit\u00f3ria Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme","family":"Pugliesi","sequence":"additional","affiliation":[{"name":"Department of Animal Reproduction, School of Veterinary Medicine and Animal Science University of S\u00e3o Paulo Pirassununga S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"622","article-title":"Use of MGA premix associated with temporary calf removal to synchronize the return heat after FTAI in calving Nelore cows","volume":"36","author":"Aono F. 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