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In the present study, we systematically reviewed and meta\u2010analysed 29 publications conducted between 1984 and 2022, focusing on seven fertility measures, clinical mastitis and milk yield in cows. We did not find statistically significant results in 8 out of 11 parameters (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05). Statistically significant results were observed for milk yield (MD: 216.25\u2009kg in 305\u2009days, <jats:italic>p<\/jats:italic>\u2009=\u2009.01, CI: 50.73\u2013381.77), pregnancy at first service (OR: 1.38 CI: 1.08\u20131.76, <jats:italic>p<\/jats:italic>\u2009=\u2009.01) and clinical mastitis (OR: 0.59, CI: 0.44\u20130.80, <jats:italic>p<\/jats:italic>\u2009=\u2009.006) in favour of beta\u2010carotene supplementation. The meta\u2010regression revealed significant effects of \u2018plasma beta\u2010carotene levels\u2019 on \u2018service to per pregnancy\u2019 and dose on \u2018milk yield\u2019 (<jats:italic>p<\/jats:italic>\u2009=\u2009.04 and <jats:italic>p<\/jats:italic>\u2009=\u20090). In binary outcomes, \u2018dose \u00d7 day\u2019 and \u2018plasma beta\u2010carotene concentration in the control group\u2019 positively influenced pregnancy at first service (<jats:italic>p<\/jats:italic>\u2009=\u2009.02 and .03). In conclusion, given the positive point direction observed for some variables and insignificant results for others, there is a need for more studies. We note the very high heterogeneity of outcomes and suggest caution in interpreting results.<\/jats:p>","DOI":"10.1111\/rda.14634","type":"journal-article","created":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T18:54:01Z","timestamp":1718132041000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The role of beta\u2010carotene in cattle infertility, mastitis and milk yield: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8901-713X","authenticated-orcid":false,"given":"An\u0131l","family":"Demeli","sequence":"first","affiliation":[{"name":"General Directorate of Food and Control  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James C.","family":"Meyer","sequence":"additional","affiliation":[{"name":"Equine Sport Science  East Hampton New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,11]]},"reference":[{"issue":"6","key":"e_1_2_9_2_1","first-page":"2737","article-title":"Scientific opinion on the safety and efficacy of beta\u2010carotene as a feed additive for all animal species and categories","volume":"10","author":"Additives E. 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