{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T03:54:38Z","timestamp":1778730878065,"version":"3.51.4"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T00:00:00Z","timestamp":1720051200000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The objectives of this experiment were to evaluate the effects of supplementation of Nellore (<jats:italic>Bos indicus<\/jats:italic>) cows with \u03b2\u2010carotene + vitamins A\u2009+\u2009D3\u2009+\u2009E\u2009+\u2009biotin on body condition score (BCS), oestrus, pregnancy, and foetal morphometry. Lactating cows (<jats:italic>n<\/jats:italic>\u2009=\u2009497) from two herds were balanced for BCS and calving period [early calving (EC); late calving (LC)] and were assigned randomly to: Control (<jats:italic>n<\/jats:italic>\u2009=\u2009251)\u2014supplementation with a mineral supplement; and SUP (<jats:italic>n<\/jats:italic>\u2009=\u2009246)\u2014supplementation with the mineral supplement fed to control + \u03b2\u2010carotene (150\u2009mg\/day)\u2009+\u2009vitamin A (40,000\u2009IU\/day)\u2009+\u2009vitamin D3 (5000\u2009IU\/day)\u2009+\u2009vitamin E (300\u2009mg\/day)\u2009+\u2009biotin (20\u2009mg\/day). Cows were supplemented from Days \u221230 to 30 (Day 0\u2009=\u2009timed artificial insemination; TAI). Pregnancy was diagnosed 30\u2009days after TAI and foetal crown\u2010rump distance and thoracic diameter were measured at 30 and 77\u2009days of gestation. Cows in the SUP treatment were more likely to have BCS \u22653.0 on Day 0 (63.0\u2009\u00b1\u20093.1 vs. 60.2\u2009\u00b1\u20093.1; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01) and were more likely to gain BCS from Days \u221230 to 30 (57.7\u2009\u00b1\u20093.3 vs. 44.1\u2009\u00b1\u20093.3%; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01). Fewer LC cows in the SUP treatment were detected in oestrus at the time of the first TAI (Control: LC: 75.4\u2009\u00b1\u20094.4 vs. SUP: LC: 64.0\u2009\u00b1\u20095.2 vs. Control: EC: 65.3\u2009\u00b1\u20094.0 vs. SUP: EC: 71.8\u2009\u00b1\u20093.7; <jats:italic>p<\/jats:italic>\u2009=\u2009.04). There was a tendency for the SUP treatment to increase pregnancy to the first TAI (64.2\u2009\u00b1\u20093.0 vs. 56.6\u2009\u00b1\u20093.1%; <jats:italic>p<\/jats:italic>\u2009=\u2009.08). A greater percentage of SUP cows was detected in oestrus at the time of the second TAI (70.1\u2009\u00b1\u20095.0 vs. 52.3\u2009\u00b1\u20094.8%; <jats:italic>p<\/jats:italic>\u2009=\u2009.01). The SUP treatment increased pregnancy to the second TAI among LC cows (SUP: LC: 75.9\u2009\u00b1\u20098.0% vs. Control: LC: 50.0\u2009\u00b1\u20098.3% vs. Control: EC: 52.0\u2009\u00b1\u20095.9% vs. SUP: EC: 41.4\u2009\u00b1\u20096.5%; <jats:italic>p<\/jats:italic>\u2009=\u2009.02). The SUP treatment increased foetal size (crown\u2010rump; <jats:italic>p<\/jats:italic>\u2009=\u2009.04 and thoracic diameter; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01) at 30\u2009days of gestation and, despite decreasing crow\u2010rump length at 77\u2009days after the first TAI among EC cows (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01), it increased the thoracic diameter at 77\u2009days after the first TAI independent of calving season. Our results support that pregnancy establishment and foetal growth can be improved when grazing Nellore cows are supplemented with \u03b2\u2010carotene and vitamins A\u2009+\u2009D3\u2009+\u2009E\u2009+\u2009biotin.<\/jats:p>","DOI":"10.1111\/rda.14660","type":"journal-article","created":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T10:20:03Z","timestamp":1720088403000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of supplementation of grazing Nellore cows with \u03b2\u2010carotene and vitamins A\u2009+\u2009D3\u2009+\u2009E\u2009+\u2009biotin on follicle diameter, oestrus, establishment of pregnancy, and foetal morphometry"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8325-6727","authenticated-orcid":false,"given":"L.","family":"Factor","sequence":"first","affiliation":[{"name":"Department of Animal Reproduction University of Sao Paulo  S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. S. F. M.","family":"Vasconcellos","sequence":"additional","affiliation":[{"name":"Innovation and Applied Science Department DSM Nutritional Products Brazil S.A  S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. V.","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Innovation and Applied Science Department DSM Nutritional Products Brazil S.A  S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Acedo","sequence":"additional","affiliation":[{"name":"Innovation and Applied Science Department DSM Nutritional Products Brazil S.A  S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Cortinhas","sequence":"additional","affiliation":[{"name":"Innovation and Applied Science Department DSM Nutritional Products Brazil S.A  S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. C.","family":"Chebel","sequence":"additional","affiliation":[{"name":"Department of Large Animal Clinical Sciences, College of Veterinary Medicine University of Florida  Gainesville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. S.","family":"Baruselli","sequence":"additional","affiliation":[{"name":"Department of Animal Reproduction University of Sao Paulo  S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,4]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/17450390109386203"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0620039"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.livsci.2008.11.004"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2014.04.026"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.21451\/1809\u20103000.rbra2021.083"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.21451\/1984\u20103143\u2010ar999"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/s175173111800054x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.3.8.2656356"},{"key":"e_1_2_10_10_1","first-page":"700","article-title":"Synergic effect of \u03b2\u2010carotene in reproductive functioning of dairy cows","volume":"8","author":"Bhatnagar P. 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