{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:44:24Z","timestamp":1753879464122,"version":"3.41.2"},"reference-count":50,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T00:00:00Z","timestamp":1721260800000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Studies investigating physiological deviations from normality in newborn calves derived from in\u00a0vitro fertilization procedures remain important for the understanding of factors that reduce calf survival after birth. The aim of this study was to investigate parameters affecting health and welfare of newborn Flemish calves derived from in\u00a0vitro embryo production (IVP) in the first hours of life in comparison to in\u00a0vivo\u2010derived calves. Physical traits of newborn calves and fetal membranes (FM) were recorded soon after birth. Newborn venous blood samples were collected at several time points within the first 24\u2009h of life for analyses of energy substrates, electrolytes, blood gases, acid\u2013base balance, blood chemistry, and haematology. A liver biopsy was taken within the first hour after birth for analysis of gene expression of key enzymes of the fructolytic and glycolytic pathways. Newborn IVP calves were heavier and larger at birth, which was associated with heavier FM. At several time points during the first 24\u2009h of life, IVP\u2010derived calves had altered rectal temperature, blood gases, electrolyte concentrations, blood parameters for liver, kidney and muscle function, and acid\u2013base balance, plasma lipid metabolism, and hemogram parameters. The relative mRNA abundances for triokinase and lactate dehydrogenase\u2010B were greater in IVP calves. In summary, IVP\u2010derived newborn calves were at higher risk of clinical problems after birth, which was markedly greater in heavier and larger calves. Such animals take longer to adapt to extrauterine life and should receive a special attention during the immediate neonatal period.<\/jats:p>","DOI":"10.1111\/rda.14676","type":"journal-article","created":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T07:25:20Z","timestamp":1721287520000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Analysis of physical traits, clinical parameters, and energy metabolism of in\u00a0vivo\u2010 and in\u00a0vitro\u2010derived Flemish newborn calves during the first day of life"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9106-4568","authenticated-orcid":false,"given":"Lu\u00eds Fernando","family":"Sch\u00fctz","sequence":"first","affiliation":[{"name":"College of Agronomy and Veterinary Medicine Santa Catarina State University (UDESC)  Lages Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiano Carminatti","family":"Zago","sequence":"additional","affiliation":[{"name":"College of Agronomy and Veterinary Medicine Santa Catarina State University (UDESC)  Lages Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu\u00eds Henrique","family":"de Aguiar","sequence":"additional","affiliation":[{"name":"College of Agronomy and Veterinary Medicine Santa Catarina State University (UDESC)  Lages Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiana","family":"Forell","sequence":"additional","affiliation":[{"name":"College of Agronomy and Veterinary Medicine Santa Catarina State University (UDESC)  Lages Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo Tondello","family":"Martins","sequence":"additional","affiliation":[{"name":"College of Agronomy and Veterinary Medicine Santa Catarina State University (UDESC)  Lages Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Urio","sequence":"additional","affiliation":[{"name":"College of Agronomy and Veterinary Medicine Santa Catarina State University (UDESC)  Lages Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro Claudino dos Santos","family":"Neto","sequence":"additional","affiliation":[{"name":"College of Agronomy and Veterinary Medicine Santa Catarina State University (UDESC)  Lages Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamir Machado","family":"Junior","sequence":"additional","affiliation":[{"name":"College of Agronomy and Veterinary Medicine Santa Catarina State University (UDESC)  Lages Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaio Cesar Simiano","family":"Tavares","sequence":"additional","affiliation":[{"name":"College of Agronomy and Veterinary Medicine Santa Catarina State University (UDESC)  Lages Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saul","family":"Gaud\u00eancio\u00a0Neto","sequence":"additional","affiliation":[{"name":"College of Agronomy and Veterinary Medicine Santa Catarina State University (UDESC)  Lages Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristiano","family":"Feltrin","sequence":"additional","affiliation":[{"name":"College of Agronomy and Veterinary Medicine Santa Catarina State University (UDESC)  Lages Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alceu","family":"Mezzalira","sequence":"additional","affiliation":[{"name":"College of Agronomy and Veterinary Medicine Santa Catarina State University (UDESC)  Lages Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo","family":"Bertolini","sequence":"additional","affiliation":[{"name":"College of Agronomy and Veterinary Medicine Santa Catarina State University (UDESC)  Lages Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,18]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Associa\u00e7\u00e3o Nacional de Criadores Herd\u2010book Collares. (n.d.)http:\/\/www.herdbook.org.br\/site\/racasbovinas\/details\/8"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/clo.2006.0037"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0093\u2010691x(95)00172\u20105"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmac043"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0093\u2010691x(02)00935\u20104"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1530\/rep.1.00188"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvfa.2008.10.002"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2013\u20106943"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod27.1.147"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2004\u20100582"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1051\/vetres:2002016"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod64.5.1375"},{"key":"e_1_2_9_14_1","first-page":"59","article-title":"Acetato de triancinolona como pr\u00e9\u2010indutor do parto de receptoras de embri\u00e3o Nelore produzidos in\u00a0vitro","volume":"10","author":"Rezende L. F. C.","year":"2009","journal-title":"Ci\u00eancia Animal Brasileira"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod52.3.676"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2005.09.022"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0093-691X(95)00363-D"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD15215"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.2.494"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2018.00668"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/jas\/skaa288"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2013.09.010"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0093\u2010691X(99)00162\u20104"},{"key":"e_1_2_9_24_1","unstructured":"Ipe D.(1987).Performing the Friedman test and the associated multiple comparison test using PROC GLM. 12th Annual SAS Users Group International Conference Dallas TX."},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022\u20100302(03)73981\u20102"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0093\u2010691X(96)00338\u2010X"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.2527\/1998.7641216x"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1900899"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378\u20104320(95)01467\u20105"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.105.040808"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0093\u2010691X(84)90310\u20108"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.animal.2023.100740"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2018.01.002"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/0093\u2010691x(85)90060\u20103"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/0093\u2010691x(88)90310\u2010x"},{"volume-title":"Estat\u00edstica aplicada \u00e0 experimenta\u00e7\u00e3o animal","year":"2002","author":"Sampaio I.","key":"e_1_2_9_36_1"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod62.6.1495"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2014\u20108359"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/0093\u2010691x(96)00174\u20104"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0093\u2010691x(02)01188\u20103"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2016\u201012539"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1017\/S2040174417000125"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod33.2.487"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod64.3.904"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02783497"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.livsci.2020.103947"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022\u20100302(91)78362\u20108"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0093\u2010691x(99)00259\u20109"},{"issue":"4","key":"e_1_2_9_49_1","article-title":"2022 Statistics of embryo production and transfer in domestic farm animals","volume":"41","author":"Viana J.","year":"2023","journal-title":"Embryo Technology Newsletter"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.103730"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1590\/1984\u20103143\u2010AR2023\u20100080"}],"container-title":["Reproduction in Domestic Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.14676","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T07:43:08Z","timestamp":1722325388000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/rda.14676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":50,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1111\/rda.14676"],"URL":"https:\/\/doi.org\/10.1111\/rda.14676","archive":["Portico"],"relation":{},"ISSN":["0936-6768","1439-0531"],"issn-type":[{"type":"print","value":"0936-6768"},{"type":"electronic","value":"1439-0531"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"2024-05-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e14676"}}