{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T04:00:06Z","timestamp":1790654406569,"version":"4.1.0"},"reference-count":83,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T00:00:00Z","timestamp":1723248000000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Ruminants are one of the world's economically important species, and their reproductive health is critical to the economic development of the livestock industry. In recent years, research on the relationship between microbiota and reproductive health has received much attention. Microbiota disruption affects the developmental health of the testes and epididymis, the male reproductive organs of the host, which in turn is related to sperm quality. Maintaining a stable microbiota protects the host from pathogens and increases breeding performance, which in turn promotes the economic development of animal husbandry. In addition, the effects and mechanisms of microbiota on reproduction were further explored. These findings support new approaches to improving and managing reproductive health in ruminants through the microbiota and facilitate further systematic exploration of microbiota\u2010mediated reproductive impacts.<\/jats:p>","DOI":"10.1111\/rda.14704","type":"journal-article","created":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T14:18:35Z","timestamp":1723299515000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effects of microbiota\u2013testis interactions on the reproductive health of male ruminants: A review"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3818-3105","authenticated-orcid":false,"given":"Cheng","family":"Pan","sequence":"first","affiliation":[{"name":"School of Life Sciences and Engineering Southwest University of Science and Technology  Mianyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangzong","family":"Zhaxi","sequence":"additional","affiliation":[{"name":"Institute of Animal Science Xizang Academy of Agricultural and Animal Husbandry Science  Lhasa China"},{"name":"Key Laboratory of Animal Genetics and Breeding on Xizang Plateau Ministry of Agriculture and Rural Affairs  Lhasa China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyan","family":"Li","sequence":"additional","affiliation":[{"name":"School of Life Sciences and Engineering Southwest University of Science and Technology  Mianyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Guan","sequence":"additional","affiliation":[{"name":"School of Life Sciences China Jiliang University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junru","family":"Pan","sequence":"additional","affiliation":[{"name":"School of Life Sciences and Engineering Southwest University of Science and Technology  Mianyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Da","family":"Wa","sequence":"additional","affiliation":[{"name":"Institute of Animal Science Xizang Academy of Agricultural and Animal Husbandry Science  Lhasa China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianzeng","family":"Song","sequence":"additional","affiliation":[{"name":"Institute of Animal Science Xizang Academy of Agricultural and Animal Husbandry Science  Lhasa China"},{"name":"Key Laboratory of Animal Genetics and Breeding on Xizang Plateau Ministry of Agriculture and Rural Affairs  Lhasa China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6339-329X","authenticated-orcid":false,"given":"Wangsheng","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Life Sciences and Engineering Southwest University of Science and Technology  Mianyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,10]]},"reference":[{"issue":"4","key":"e_1_2_12_2_1","article-title":"The fate of Leydig cells in men with Spermatogenic failure","volume":"12","author":"Adamczewska D.","year":"2022","journal-title":"Life (Basel)"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2018.12.002"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/10915818909014532"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1346035"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2015.00021"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2017.06.025"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2020.00373"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2014.1897"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox11050970"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.48692"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-023-01581-3"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/andr.12486"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/andr.12882"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2022.108238"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11259-023-10209-8"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2016.01.019"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40104-017-0166-4"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2017.10.025"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2019-319127"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/and.13721"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12958-019-0510-y"},{"key":"e_1_2_12_23_1","first-page":"1","article-title":"The gut microbiota contributes to the development of LPS\u2010induced Orchitis by disrupting the blood\u2010testosterone barrier in mice[J]","author":"Guo Q.","year":"2024","journal-title":"Reproductive Sciences"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.07.043"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2019.135077"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aninu.2020.11.005"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmv016"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2017-02799"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/vms3.133"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2020.110964"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2018.02.019"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/biolre\/iox096"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.851386"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.1042923"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/jas\/skad189"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s43032-021-00624-0"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/jas\/skac367"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2023.1049093"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2022.113225"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.863315"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/cm.21338"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2021.150368"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2022.113623"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11259-023-10116-y"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-309990"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/aja.2011.40"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceb.2013.07.009"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2022.867671"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.199644"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2015.1134082"},{"issue":"3","key":"e_1_2_12_51_1","doi-asserted-by":"crossref","DOI":"10.36660\/abc.20230138i","article-title":"Testosterone deficiency in hypertensive men: Prevalence and associated factors","volume":"121","author":"Negretto L.","year":"2024","journal-title":"Arquivos Brasileiros de Cardiologia"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1262\/jrd.2018-077"},{"issue":"2","key":"e_1_2_12_53_1","first-page":"222","article-title":"Microbiota and reproduction in agricultural mammals","volume":"57","author":"Popov D. V.","year":"2022","journal-title":"Agricultural Biology"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm12081335"},{"key":"e_1_2_12_55_1","first-page":"58","article-title":"Evaluation of the fecal microbes in pre\u2010adult, adult and castrated male goats (Capra hircus)","volume":"11","author":"Saravanan G.","year":"2022","journal-title":"Bulletin of Environment, Pharmacology and Life Sciences"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4185"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2009-0016"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-024-10272-8"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resmic.2019.03.003"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2974"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1293\/tox.2021-0025"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12915-022-01326-y"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00009.2020"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature18847"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.3920\/BM2016.0122"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu11040843"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2021.05.009"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani13060996"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8091297"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-024-03894-7"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.2000.9635"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.15252\/embr.202050663"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2008.00919.x"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.4236\/ojas.2014.41004"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-018-1735-9"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.1093\/femsec\/fiab009"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2020-320992"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2020-323347"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2019.08.006"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.43189"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40104-022-00687-2"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2023.1308484"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2022.989908"},{"key":"e_1_2_12_84_1","article-title":"\"comparative analysis of intestinal microbiota composition between free\u2010ranged captive yak populations in Nimu County.\" Frontiers in cellular and infection","volume":"14","author":"Zhu Y.","year":"2024","journal-title":"Microbiology"}],"container-title":["Reproduction in Domestic Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.14704","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T05:23:59Z","timestamp":1724909039000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/rda.14704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":83,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1111\/rda.14704"],"URL":"https:\/\/doi.org\/10.1111\/rda.14704","archive":["Portico"],"relation":{},"ISSN":["0936-6768","1439-0531"],"issn-type":[{"value":"0936-6768","type":"print"},{"value":"1439-0531","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"2024-05-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e14704"}}