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Formalin\u2010fixed placental samples from 11 mixed\u2010breed bitches have been assigned to the \u2018early\u2019 or the \u2018mature\u2019 placenta group, processed by the routine histological technique and labelled with a panel of 14 biotinylated lectins. The glycan distribution was almost completely preserved over pregnancy. Cytotrophoblast cells expressed high\u2010mannose <jats:italic>N<\/jats:italic>\u2010linked residues and <jats:italic>N<\/jats:italic>\u2010acetyl\u2010D\u2010glucosamine, whereas mannose <jats:italic>N<\/jats:italic>\u2010linked residues, <jats:italic>N<\/jats:italic>\u2010acetyl\u2010D\u2010glucosamine and \u03b2\u2010 and \u03b1\u2010D\u2010galactose\/<jats:italic>N<\/jats:italic>\u2010acetyl\u2010D\u2010galactosamine have been found in the syncytiotrophoblast. The maternal and foetal endothelial binding pattern was enriched in \u03b2\u2010D\u2010galactose, \u03b1\u2010D\u2010mannose in non\u2010bisected bi\/tri\u2010antennary <jats:italic>N\u2010<\/jats:italic>linked complex and Gal<jats:italic>\u03b1<\/jats:italic>1,3Gal\u2010Gal<jats:italic>\u03b1<\/jats:italic>1,4Gal. Both deep and superficial glands showed a great variety of glycoconjugates, such as D\u2010mannose, D\u2010glucose, <jats:italic>N<\/jats:italic>\u2010acetyl\u2010D\u2010glucosamine, <jats:italic>N<\/jats:italic>\u2010acetyl\u2010D\u2010galactosamine, galactose, <jats:italic>N<\/jats:italic>\u2010acetylneuraminic acid and fucose. Most results in this study were consistent with those previously reported in canine and feline mature placentas; here, early placentas have been analysed and the lectin binding pattern of mature placentas has been further described. These studies on canine placentas contribute to detecting and understanding glycome changes in pathophysiological conditions.<\/jats:p>","DOI":"10.1111\/rda.14750","type":"journal-article","created":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T13:55:18Z","timestamp":1733234118000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Glycosylation in Canine Placentas"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5513-8395","authenticated-orcid":false,"given":"Carolina N.","family":"Zanuzzi","sequence":"first","affiliation":[{"name":"Laboratorio de Histolog\u00eda y Embriolog\u00eda Descriptiva, Experimental y Comparada (LHYEDEC), Facultad de Ciencias Veterinarias Universidad Nacional de La Plata (FCV, UNLP)  La Plata Argentina"},{"name":"Centro Cient\u00edfico Tecnol\u00f3gico (CCT) Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas (CONICET)  Buenos Aires 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