{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T03:12:14Z","timestamp":1788318734779,"version":"build-2803163510"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T00:00:00Z","timestamp":1740096000000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Improvement of yield characteristics in animal breeding is important in terms of increasing animal production and sustainability. Fertility is one of the most important yield traits affecting economic gain in sheep breeding. Anti\u2010M\u00fcllerian Hormone (AMH) is widely recognised as a dependable biomarker for assessing ovarian reserves and fertility potential. The aim of this study was to evaluate the dynamics of AMH during different phases of the sexual cycle in Norduz ewes the non\u2010breeding season. Additionally, the study sought to assess the effects of age and body condition score (BCS) on AMH concentrations during these phases. A total of 32 Norduz ewes with a body condition score (BCS) of 3\u20134.5 and aged between 2 and 4\u2009years were used as animal material in the study. All experimental procedures were carried out outside the breeding season and when the ewes were lactating. In all ewes in anestrus, intravaginal sponges (Esponjavet, 60\u2009mg MAP, Hipra, Turkey) were kept in the vagina for 7\u2009days for estrus synchronisation. Intramuscular injections of PMSG (Oviser, 500\u2009IU, Hipra, Turkey) and PGF2\u03b1 analog (Gestavet, 50\u2009\u03bcg, Hipra, Turkey) were administered 48\u2009h prior to sponge removal. Twenty\u2010four hours after sponge removal, ewes were exposed to the ram for estrus detection. Since 5 ewes did not show estrus, blood samples were collected regularly from animals (<jats:italic>n<\/jats:italic>\u2009=\u200927) in which estrus was detected at three different stages: one just before the insertion of vaginal sponges (anestrus), another when heat was detected exposing to the ram (estrus), and the final one 10\u2009days after estrus (diestrus). The serum samples were assessed for the levels of AMH and progesterone through the electrochemiluminessence immunoassay technique (ECLIA). The results of the analyses showed that serum AMH concentration did not vary between anestrus, estrus and diestrus phases of the sexual cycle of Norduz ewes outside the breeding season (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). Furthermore, age and BCS had no effect on progesterone and AMH levels in different phases of the sexual cycle (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). In conclusion, this study shows that serum AMH levels are constant at any stage of the estrus cycle. This suggests that phenotypic evaluation of ewes can be performed with a single measurement and that AMH is a reproducible and dependable biomarker that can be measured at any stage of the estrus cycle at an arbitrary time point.<\/jats:p>","DOI":"10.1111\/rda.70010","type":"journal-article","created":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:44:19Z","timestamp":1740127459000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Anti\u2010M\u00fcllerian Hormone Concentrations Can Be Reliably Determined by a Single Measurement, Irrespective of Cycle, in Synchronised Ewes During Non\u2010Breeding Season"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6073-4215","authenticated-orcid":false,"given":"Nebi","family":"Cetin","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine Van Yuzuncu Yil University  Van Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7962-6959","authenticated-orcid":false,"given":"Davut","family":"Koca","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine Van Yuzuncu Yil University  Van Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.4236\/arsci.2020.81005"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2019.11.041"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/rda.13583"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/vetsci8010005"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(86)90783-X"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/biolre\/iox069"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/vms3.1269"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD10226"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.108.071670"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.4236\/ojvm.2023.131001"},{"issue":"2","key":"e_1_2_10_12_1","first-page":"151","article-title":"Recherches Sur La Differenciation Sexuelle De Lembryon De Lapin. 1. 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