{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:44:58Z","timestamp":1785451498163,"version":"3.56.0"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T00:00:00Z","timestamp":1740441600000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004951","name":"Atat\u00fcrk \u00dcniversitesi","doi-asserted-by":"publisher","award":["TYL\u20102023\u201013244"],"award-info":[{"award-number":["TYL\u20102023\u201013244"]}],"id":[{"id":"10.13039\/501100004951","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Asprosin, a protein hormone that regulates hunger and glucose homeostasis, is produced by white adipose tissue. The aim of this study was to investigate the effect of asprosin level on fertility and oxidative stress parameters in Simmental cows. In the study, 44 Simmental multiparous cows were used. PRID was used to synchronise the animals. Blood samples were obtained from the cattle on the day of artificial insemination, and the amount of asprosin was measured. Animals were divided into two groups: a low asprosin (LA) group and a high asprosin (HA) group. On day 25, blood samples were taken, and pregnancy\u2010associated glycoprotein (PAG2), total antioxidant level (TAS) and total oxidant level (TOS) were measured using commercial kits. Ultrasonography was used to diagnose pregnancy on day 45. The TAS level at day 25 was higher in the HA group than the TAS level at the beginning of the study (<jats:italic>p<\/jats:italic>\u2009=\u20090.007). The TOS level at the beginning of the study was higher in the HA group than in the LA group (<jats:italic>p<\/jats:italic>\u2009=\u20090.017). The TOS level of cows in the LA group on day 25 was significantly higher than the TOS level at the beginning of the study (<jats:italic>p<\/jats:italic>\u2009=\u20090.028). In conclusion, asprosin levels in cows affected oxidative stress parameters. According to receiver operating characteristic curve (ROC) analysis, there was a strong correlation between TOS and asprosin, and it was concluded that cows with HA values may be exposed to oxidative stress.<\/jats:p>","DOI":"10.1111\/rda.70022","type":"journal-article","created":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T22:57:10Z","timestamp":1741647430000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Investigation of the Effect of Asprosin Level on Fertility Success and Oxidative Stress in Simmental Cows"],"prefix":"10.1111","volume":"60","author":[{"given":"Rahmi","family":"K\u00f6se","sequence":"first","affiliation":[{"name":"Department of Reproduction and Artificial Insemination, Faculty of Veterinary Medicine Ataturk University  Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4450-6540","authenticated-orcid":false,"given":"Serkan Ali","family":"Akarsu","sequence":"additional","affiliation":[{"name":"Department of Reproduction and Artificial Insemination, Faculty of Veterinary Medicine Ataturk University  Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serdal","family":"Kurt","sequence":"additional","affiliation":[{"name":"Department of Veterinary Elbistan Vocational School, Kahramanmaras Istiklal University, Kahramanmaras  Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hakan","family":"Serin","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Faculty of Veterinary Medicine Sel\u00e7uk University  Konya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet Akif","family":"Ayd\u0131n","sequence":"additional","affiliation":[{"name":"Department of Reproduction and Artificial Insemination, Faculty of Veterinary Medicine Kafkas University  Kars Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Karahanl\u0131","sequence":"additional","affiliation":[{"name":"Department of Reproduction and Artificial Insemination, Faculty of Veterinary Medicine Ataturk University  Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamze","family":"U\u00e7ak","sequence":"additional","affiliation":[{"name":"Department of Reproduction and Artificial Insemination, Faculty of Veterinary Medicine Ataturk University  Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Y\u00f6r\u00fc","sequence":"additional","affiliation":[{"name":"Department of Reproduction and Artificial Insemination, Faculty of Veterinary Medicine Ataturk University  Erzurum Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,25]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpn.12273"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpn.12365"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.5505\/abantmedj.2013.97269"},{"key":"e_1_2_10_5_1","volume-title":"Exploration of the Relationship Between Asprosin With Oxidative Stress Index in Obese Iraqi Patients","author":"Alsajri A.","year":"2022"},{"issue":"1","key":"e_1_2_10_6_1","first-page":"1","article-title":"Relationship Between Oxidative Stress Status and Glycoprotein\u2010Associated Pregnancy Concentrations During the Early Pregnancy Period in Dairy Cows","volume":"4","author":"Ayad A.","year":"2020","journal-title":"Turkish Journal of Veterinary Research"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10121918"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani12162033"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2016.04.039"},{"key":"e_1_2_10_10_1","volume-title":"Effects of Asprosin on Steroidogeneses of Bovine Granulosa Cells","author":"Batalha I. 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