{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T06:59:37Z","timestamp":1773817177952,"version":"3.50.1"},"reference-count":50,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T00:00:00Z","timestamp":1768608000000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Differences in clinicochemical serum parameters of gestating\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Bos taurus taurus<\/jats:italic>\n                    <\/jats:styled-content>\n                    (taurine, Angus) and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Bos taurus indicus<\/jats:italic>\n                    <\/jats:styled-content>\n                    (indicine, Brahman) cattle and the relationships of such parameters with conceptus phenotype are largely unexplored. We determined the concentrations of 21 electrolytes, metabolites and enzymes in serum of Angus and Brahman dams at early (Day 48,\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200924) and midgestation (Day 153,\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200937) and examined relationships with embryo, fetal and placental weights. At early gestation, ionised calcium (+26%), magnesium (+7%), lactate (+32%), total protein (+6%) and alanine transaminase (ALT, +39%) were significantly (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05) higher in Angus than in Brahman. At midgestation, ionised (+15%) and total calcium (+4%), magnesium (+11%), sodium (+2%), calcium\/phosphorus ratio (+25%) and albumin (+5%) were higher (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05) in Angus cows. Ionised calcium, magnesium, sodium, albumin, lactate and ALT correlated positively with embryo, fetal and\/or placental weights (\n                    <jats:italic>r<\/jats:italic>\n                    \u2009=\u20090.31\u20130.48,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05), while calcium\/phosphorus ratio correlated negatively with Day 48 placental weight (\n                    <jats:italic>r<\/jats:italic>\n                    \u2009=\u2009\u22120.51,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). Serum creatinine (+21%), glucose (+15%), triglycerides (+16%), alkaline phosphatase (ALP, +73%) and glutamate dehydrogenase (GLDH, +44%) levels were higher (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05) in Brahman at midgestation. Creatinine, glucose and ALP correlated negatively with fetal and placental weights at midgestation (\n                    <jats:italic>r<\/jats:italic>\n                    \u2009=\u2009\u22120.37 to \u22120.48,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05\u20130.01). Our data demonstrate genetic effects on maternal blood composition that reflect differences in maternal physiology of gestating taurine and indicine cattle which may affect conceptus growth and birthweight.\n                  <\/jats:p>","DOI":"10.1111\/rda.70163","type":"journal-article","created":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T08:36:18Z","timestamp":1768638978000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Differences in Clinicochemical Serum Parameters of Gestating\n                    <i>Bos taurus taurus<\/i>\n                    and\n                    <i>Bos taurus indicus<\/i>\n                    Cattle and Relationships With Embryo\u2010Fetal and Placental Weights"],"prefix":"10.1111","volume":"61","author":[{"given":"Entesar","family":"Shuaib","sequence":"first","affiliation":[{"name":"Robinson Research Institute The University of Adelaide  Adelaide South Australia Australia"},{"name":"Davies Livestock Research Centre, School of Animal and Veterinary Sciences The University of Adelaide  Roseworthy South Australia Australia"},{"name":"School of Animal and Veterinary Sciences The University of Adelaide  Roseworthy South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian","family":"Beckman","sequence":"additional","affiliation":[{"name":"School of Animal and Veterinary Sciences The University of Adelaide  Roseworthy South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milton M.","family":"McAllister","sequence":"additional","affiliation":[{"name":"School of Animal and Veterinary Sciences The University of Adelaide  Roseworthy South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Gr\u00fctzner","sequence":"additional","affiliation":[{"name":"Robinson Research Institute The University of Adelaide  Adelaide South Australia Australia"},{"name":"Genetics and Evolution, School of Biological Sciences The University of Adelaide  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan L.","family":"Wright","sequence":"additional","affiliation":[{"name":"Robinson Research Institute The University of Adelaide  Adelaide South Australia Australia"},{"name":"Genetics and Evolution, School of Biological Sciences The University of Adelaide  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Hiendleder","sequence":"additional","affiliation":[{"name":"Robinson Research Institute The University of Adelaide  Adelaide South Australia Australia"},{"name":"Davies Livestock Research Centre, School of Animal and Veterinary Sciences The University of Adelaide  Roseworthy South Australia Australia"},{"name":"School of Animal and Veterinary Sciences The University of Adelaide  Roseworthy South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4674-9207","authenticated-orcid":false,"given":"Karen L.","family":"Kind","sequence":"additional","affiliation":[{"name":"Robinson Research Institute The University of Adelaide  Adelaide South Australia Australia"},{"name":"Davies Livestock Research Centre, School of Animal and Veterinary Sciences The University of Adelaide  Roseworthy South Australia Australia"},{"name":"School of Animal and Veterinary Sciences The University of Adelaide  Roseworthy South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,17]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0019821"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439\u20100531.2009.01345.x"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-53367-6.00001-7"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.22358\/jafs\/74068\/2004"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026336505343"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408363.2021.1978923"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-370491-7.00016-7"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.2527\/1993.712326x"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2007.01.010"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.2527\/2001.7951151x"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1976.sp011532"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471\u20100528.14237"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.2527\/jas.2008\u20101553"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022\u20100302(60)90118\u20101"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2017.04.009"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939\u2010165X.2007.tb00216.x"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4684-8872-2_1"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.2527\/1991.6951945x"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.2527\/1991.6951954x"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042\u20103306.1997.tb05074.x"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102826.2008.01663.x"},{"issue":"1","key":"e_1_2_11_23_1","first-page":"52","article-title":"Metabolic Profile Variation and Reproduction Performance in Holstein Cows of Different Milk Yields in Southern Brazil","volume":"26","author":"Gonzalez F. H. D.","year":"1998","journal-title":"Arquivos da Faculdade de Veterin\u00e1ria, UFRGS"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.2527\/jas1989.67123463x"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.2527\/af.2017\u20100127"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/30.1.15"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1159\/000118756"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022\u20100302(93)77639\u20100"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1203\/00006450\u2010200102000\u201000003"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.66.509"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00027.2015"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.2527\/jas1953.124765x"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471\u20100528.2008.01709.x"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010020\u201015848\u2010y"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1017\/s0954422417000257"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002\u20109378(95)90187\u20106"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13020490"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2018.01091"},{"key":"e_1_2_11_39_1","volume-title":"Nutrient Requirements of Beef Cattle: Seventh Revised Edition: Update 2000","author":"National Research Council","year":"2000"},{"issue":"9","key":"e_1_2_11_40_1","first-page":"2223","article-title":"Metabolic Characteristics of Multiparous Angus and Brahman Cows Grazing in the Chihuahuan Desert","volume":"80","author":"Obeidat B. S.","year":"2002","journal-title":"Journal of Animal Science"},{"key":"e_1_2_11_41_1","unstructured":"R Core Team.2023.\u201cR: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing.\u201dhttps:\/\/www.R\u2010project.org\/."},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/biolre\/ioad052"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12929\u2010016\u20100233\u20108"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2016.04.016"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1590\/s1516\u201035982012000300046"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1093\/biolre\/ioab063"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0034\u20105288(18)31892\u20107"},{"key":"e_1_2_11_48_1","volume-title":"Exploratory Data Analysis","author":"Tukey J. W.","year":"1977"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.2527\/jas1980.5061201x"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.2263"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1385\/bter:109:3:255"}],"container-title":["Reproduction in Domestic Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.70163","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/rda.70163","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.70163","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T05:59:00Z","timestamp":1773813540000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/rda.70163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1111\/rda.70163"],"URL":"https:\/\/doi.org\/10.1111\/rda.70163","archive":["Portico"],"relation":{},"ISSN":["0936-6768","1439-0531"],"issn-type":[{"value":"0936-6768","type":"print"},{"value":"1439-0531","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-06-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70163"}}