{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T04:10:04Z","timestamp":1773029404778,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100011893","name":"Instituto Nacional de Investigaciones Forestales, Agr\u00edcolas y Pecuarias","doi-asserted-by":"publisher","award":["12331636360"],"award-info":[{"award-number":["12331636360"]}],"id":[{"id":"10.13039\/501100011893","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Maternal nutrition during gestation critically influences foetal reproductive programming. To clarify inconsistent evidence, a meta\u2010analysis was performed to assess the effect of maternal nutritional restriction on the number of Sertoli cells in ovine offspring. A systematic review in PubMed, Google Scholar, Scopus and Science Direct identified three studies (four comparisons;\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200952). Standardised mean differences (Hedges'\n                    <jats:italic>g<\/jats:italic>\n                    ) were calculated using a random\u2010effects model. The pooled effect was significant (\n                    <jats:italic>g<\/jats:italic>\n                    \u2009=\u2009\u22120.95, 95% CI: \u22121.49 to \u22120.41;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), with no heterogeneity (\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u20090%) or publication bias (Egger's test\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.616). In conclusion, maternal undernutrition reduces Sertoli cell numbers by approximately one standard deviation.\n                  <\/jats:p>","DOI":"10.1111\/rda.70185","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T13:09:57Z","timestamp":1770728997000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Ewe Nutritional Restriction During Gestation on the Number of Sertoli Cells in the Offspring: A Meta\u2010Analysis"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7825-5888","authenticated-orcid":false,"given":"Mario A.","family":"Espinosa\u2010Mart\u00ednez","sequence":"first","affiliation":[{"name":"CENID Fisiolog\u00eda y Mejoramiento Animal\u2010INIFAP, Col\u00f3n  Quer\u00e9taro Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3082-0942","authenticated-orcid":false,"given":"H\u00e9ctor","family":"Jim\u00e9nez\u2010Severiano","sequence":"additional","affiliation":[{"name":"CENID Fisiolog\u00eda y Mejoramiento Animal\u2010INIFAP, Col\u00f3n  Quer\u00e9taro Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3423-8466","authenticated-orcid":false,"given":"Luis J.","family":"Montiel\u2010Olgu\u00edn","sequence":"additional","affiliation":[{"name":"CENID Fisiolog\u00eda y Mejoramiento Animal\u2010INIFAP, Col\u00f3n  Quer\u00e9taro Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477\u20105751\u201012\u20102"},{"key":"e_1_2_11_3_1","first-page":"51","article-title":"Effects of Maternal Nutrition During Pregnancy on the Growth and Reproductive Development of Male Sheep: A Meta\u2010Analysis","volume":"72","author":"Asmad K.","year":"2012","journal-title":"Proceedings of the New Zealand Society of Animal Production"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD02046"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1530\/rep.0.1220375"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378\u20104320(96)01471\u20106"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2015.09.002"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.02.017"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2017.12.23"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/123610"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2008.08.017"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.2527\/jas.2015\u20109020"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrd.22974"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378\u20104320(02)00068\u20104"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/jas\/sky072"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2010.05.001"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.livsci.2024.205428"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP\u201023\u20100074"}],"container-title":["Reproduction in Domestic Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.70185","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/rda.70185","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.70185","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T03:26:09Z","timestamp":1773026769000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/rda.70185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1111\/rda.70185"],"URL":"https:\/\/doi.org\/10.1111\/rda.70185","archive":["Portico"],"relation":{},"ISSN":["0936-6768","1439-0531"],"issn-type":[{"value":"0936-6768","type":"print"},{"value":"1439-0531","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"2025-10-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70185"}}