{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T17:48:09Z","timestamp":1790876889280,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"S3","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["PID2022\u2010136561OB\u2010I00"],"award-info":[{"award-number":["PID2022\u2010136561OB\u2010I00"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["CNS2023\u2010144564"],"award-info":[{"award-number":["CNS2023\u2010144564"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Sperm motility is a key parameter for male selection and is closely linked to male fertility status. miRNAs have been proposed as fertility biomarkers, and their regulatory effects on sperm motility have been previously investigated. In the present study, the miRNA cargo from three different sources, seminal extracellular vesicles, free transcripts in seminal plasma and spermatozoa, was analysed from semen samples with high motility and reduced motility. Three differentially expressed miRNAs were identified in seminal extracellular vesicles (miR\u20106529\u20105p, miR\u2010146a\u20105p and miR\u201015a\u20105p), two in seminal plasma (miR\u2010532\u20105p and miR\u201098\u20105p) and one in spermatozoa (miR\u20101468\u20105p). These miRNAs have been reported to play regulatory roles in other species that may be associated with sperm motility, and could therefore potentially serve as motility\u2010related biomarkers.<\/jats:p>","DOI":"10.1111\/rda.70221","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:12:10Z","timestamp":1790827930000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Differentially expressed\n                    <scp>miRNA<\/scp>\n                    Cargo From Boar Seminal Extracellular Vesicles Is Linked With Motility Quality in\n                    <scp>AI<\/scp>\n                    Doses"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4904-1570","authenticated-orcid":false,"given":"Adri\u00e1n","family":"Mart\u00edn\u2010San Juan","sequence":"first","affiliation":[{"name":"Department of Animal Reproduction Spanish National Institute for Agricultural and Food Research and Technology (INIA\u2010CSIC)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Cerrato Mart\u00edn\u2010Hinojal","sequence":"additional","affiliation":[{"name":"Department of Animal Reproduction Spanish National Institute for Agricultural and Food Research and Technology (INIA\u2010CSIC)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena","family":"Nieto\u2010Crist\u00f3bal","sequence":"additional","affiliation":[{"name":"Department of Animal Reproduction Spanish National Institute for Agricultural and Food Research and Technology (INIA\u2010CSIC)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Jos\u00e9","family":"Martinez\u2010Alborcia","sequence":"additional","affiliation":[{"name":"Topigs Norsvin Espa\u00f1a SLU\u2010AIM Ib\u00e9rica  Las Rozas Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"de Mercado","sequence":"additional","affiliation":[{"name":"Department of Animal Reproduction Spanish National Institute for Agricultural and Food Research and Technology (INIA\u2010CSIC)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"\u00c1lvarez\u2010Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Department of Animal Reproduction Spanish National Institute for Agricultural and Food Research and Technology (INIA\u2010CSIC)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP\u201013\u20100358"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2020.11.015"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.00791"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11033\u2010021\u201006593\u20106"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2024.02.007"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2016.07.012"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jim.2009.12.007"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2011.06.025"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42003\u2010022\u201003954\u20100"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/and.13412"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/andr.70153"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2022.107051"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jev2.12404"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.114.126672"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.4103\/aja20238"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2023.11.028"}],"container-title":["Reproduction in Domestic Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.70221","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/rda.70221","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.70221","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:46:06Z","timestamp":1790837166000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/rda.70221"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,30]]},"references-count":16,"journal-issue":{"issue":"S3","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1111\/rda.70221"],"URL":"https:\/\/doi.org\/10.1111\/rda.70221","archive":["Portico"],"relation":{},"ISSN":["0936-6768","1439-0531"],"issn-type":[{"value":"0936-6768","type":"print"},{"value":"1439-0531","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,30]]},"assertion":[{"value":"2026-03-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70221"}}