{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T03:17:19Z","timestamp":1788405439998,"version":"build-2803163510"},"reference-count":90,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001584","name":"Department of Agriculture, Food and the Marine, Ireland","doi-asserted-by":"publisher","award":["(10.13039\/501100001584)*2021R665"],"award-info":[{"award-number":["(10.13039\/501100001584)*2021R665"]}],"id":[{"id":"10.13039\/501100001584","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Reprod Domestic Animals"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Bovine embryo transfer (ET) has been a consistently growing market worldwide with in\u00a0vitro produced (IVP) embryos now far outnumbering those produced by traditional superovulation. Because transfer of a viable blastocyst\u2010stage embryo to the uterus bypasses many of the potential biological causes of early pregnancy failure associated with artificial insemination (AI; anovulation, sperm transport, fertilization failure, early embryonic death), pregnancy success should logically be higher following ET than following AI. However, this is not always the case. One of the main factors contributing to this paradox is pregnancy loss following ET, particularly with IVP embryos. This greater embryo mortality presents a significant obstacle to more widespread use of IVP embryos. Improvements in embryo culture media as well as in our understanding of the underlying physiological and molecular regulation of early embryo development and embryo\u2010maternal communication leading to a successful pregnancy will significantly contribute to improved reproductive efficiency and sustainability in agri\u2010food production.<\/jats:p>","DOI":"10.1111\/rda.70283","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T02:52:52Z","timestamp":1788403972000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pregnancy Outcomes Following Artificial Insemination and Embryo Transfer in Dairy Cows\u2014Expectations vs. Reality"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3981-4269","authenticated-orcid":false,"given":"Ana Clara Canto","family":"Souza","sequence":"first","affiliation":[{"name":"School of Agriculture and Food Science University College Dublin  Dublin 4 Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5598-5044","authenticated-orcid":false,"given":"Pat","family":"Lonergan","sequence":"additional","affiliation":[{"name":"School of Agriculture and Food Science University College Dublin  Dublin 4 Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,2]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2025.117561"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2020.04.028"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0811841106"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP\u201017\u20100257"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2021\u201021773"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2020\u201019519"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2018\u201014992"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/pnasnexus\/pgad284"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2025\u201028099"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod26.5.925"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.animal.2023.100775"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1751731114000512"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP\u201008\u20100242"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2024\u201025221"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2021\u201020281"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2023\u201023520"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2024\u201025139"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2024\u201025725"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/biolre\/ioag121"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.3168\/jdsc.2022\u20100282"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2020\u201019070"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.2527\/animalsci2002.80E\u2010Suppl_21a"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP\u201017\u20100432"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP\u201013\u20100010"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/wdev.220"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2021\u201021431"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.3168\/jdsc.2022\u20100280"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/biolre\/ioy256"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.animal.2023.100828"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2017\u201013223"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010animal\u2010021419\u2010084010"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/jas\/skaa288"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.animal.2023.100745"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/biolre\/ioae052"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2012.08.007"},{"issue":"3","key":"e_1_2_11_37_1","first-page":"59","article-title":"Cavity Corpus Luteum in Lactating Dairy Cows Receiving Embryo Transfer: Impacts on Fertility and Pregnancy Maintenance","volume":"22","author":"Lamim R. A.","year":"2025","journal-title":"Animal Reproduction"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1017\/S175173111800071X"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1590\/1984\u20103143\u2010AR2025\u20100055"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2007.09.007"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.103.018168"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1530\/rep.0.1260337"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2020\u201018583"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.3168\/jdsc.2025\u20100840"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2021.635565"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2011\u20105270"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.111.092643"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0812722106"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD25156"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2018\u201014410"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/biolre\/ioy199"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2018\u201015828"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2018\u201015961"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1093\/biolre\/ioae102"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1721191115"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2025\u201027056"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1071\/RDv32n2Ab10"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP\u201011\u20100374"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2015\u201010192"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.animal.2023.100746"},{"key":"e_1_2_11_61_1","unstructured":"Quinton H.2025.\u201cCommercial Embryo Transfer Activity in Europe 2024. Proceedings of the 41st Scientific Meeting of the Association of Embryo Technology in Europe.\u201d9\u201316."},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrep.2024.101772"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202201977R"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2009\u20102605"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrd.10138"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD11139"},{"key":"e_1_2_11_67_1","first-page":"S3","article-title":"How FTAI and FTET Impact Reproductive Efficiency of Brazilian Dairy Herds","volume":"39","author":"Rodrigues C. A.","year":"2011","journal-title":"Acta Scientiae Veterinariae"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2021.635497"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaz6830"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.1590\/1984\u20103143\u2010AR2025\u20100048"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2015.11.029"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.21451\/1984\u20103143\u2010ar995"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.1093\/biolre\/ioz060"},{"key":"e_1_2_11_74_1","doi-asserted-by":"publisher","DOI":"10.1111\/rda.13297"},{"key":"e_1_2_11_75_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022\u20100302(02)74370\u20101"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2022\u201022553"},{"key":"e_1_2_11_77_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD09221"},{"key":"e_1_2_11_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.animal.2023.100769"},{"key":"e_1_2_11_79_1","first-page":"38","volume-title":"BioPRYN, a Measure of Pregnancy\u2010Specific Protein B for Detection of Pregnancy in Ruminant Animals","author":"Sasser R.","year":"2009"},{"key":"e_1_2_11_80_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod35.4.936"},{"key":"e_1_2_11_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2024.109605"},{"key":"e_1_2_11_82_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP\u201013\u20100165"},{"key":"e_1_2_11_83_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2010\u20104008"},{"key":"e_1_2_11_84_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0129787"},{"issue":"3","key":"e_1_2_11_85_1","first-page":"81","article-title":"Factors Affecting Efficiency of Artificial Insemination or Transfer of In\u00a0Vitro Produced Embryos in Dairy Herds","volume":"21","author":"Vandresen C. C.","year":"2024","journal-title":"Animal Reproduction"},{"issue":"4","key":"e_1_2_11_86_1","first-page":"33","article-title":"2024 Statistics of Embryo Production and Transfer in Domestic Farm Animals: Over Two Million Cattle Embryos Were Produced In\u00a0Vitro worldwide, More Than Sevenfold the Number of Those Collected In\u00a0Vivo","volume":"43","author":"Viana J. H. M.","year":"2025","journal-title":"Embryo Technology Newsletter, Issue"},{"key":"e_1_2_11_87_1","first-page":"690","article-title":"Effect of Different Reproductive Biotechnologies (AI, ET\u2010in Vivo and ET\u2010in Vitro) on Reproductive Performance of Holstein Females","volume":"14","author":"Viziack M. P.","year":"2017","journal-title":"Animal Reproduction"},{"key":"e_1_2_11_88_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001590305"},{"key":"e_1_2_11_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2016.04.037"},{"key":"e_1_2_11_90_1","doi-asserted-by":"publisher","DOI":"10.21203\/rs.3.rs-8509201\/v1"},{"key":"e_1_2_11_91_1","doi-asserted-by":"publisher","DOI":"10.1093\/biolre\/ioac107"}],"container-title":["Reproduction in Domestic Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.70283","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/rda.70283","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/rda.70283","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T03:10:01Z","timestamp":1788405001000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/rda.70283"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":90,"journal-issue":{"issue":"S2","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/rda.70283"],"URL":"https:\/\/doi.org\/10.1111\/rda.70283","archive":["Portico"],"relation":{},"ISSN":["0936-6768","1439-0531"],"issn-type":[{"value":"0936-6768","type":"print"},{"value":"1439-0531","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"2026-04-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70283"}}