{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T19:31:15Z","timestamp":1765827075092},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,7,25]],"date-time":"2013-07-25T00:00:00Z","timestamp":1374710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and objective<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">COPD A<\/jats:styled-content>ssessment <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>est (<jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content>) is a recently introduced, simple\u2010to\u2010use health status instrument that takes less time to complete than better\u2010established health status instruments. In chronic obstructive pulmonary disease (<jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content>) patients, the <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content> improves with pulmonary rehabilitation (<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>), and changes correlate with improvements in longer\u2010established health status instruments such as the <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hronic <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>espiratory <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>uestionnaire (<jats:styled-content style=\"fixed-case\">CRQ<\/jats:styled-content>). Increasing numbers of non\u2010<jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> patients are referred for <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>, but it is not known whether the <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content> is responsive to <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content> in these populations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content> score was prospectively measured in 365 consecutive patients (255 <jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content>, 110 non\u2010<jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content>) before and after an 8\u2010week <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content> programme. Pre to post change in <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content> was calculated for <jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> and non\u2010<jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> patients, and correlated with change in the <jats:styled-content style=\"fixed-case\">CRQ<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For both non\u2010<jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> patients, there was a similar and significant improvement in the mean (95% confidence interval) <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content> score following <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content> (non\u2010<jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content>: \u22122.1 (\u22121.0, \u22123.2) vs <jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content>: \u22123.0 (\u22122.2, \u22123.8); <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content><\/jats:italic>\u2009=\u20090.19). Change in <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content> was significantly correlated with all domains of the <jats:styled-content style=\"fixed-case\">CRQ<\/jats:styled-content> in non\u2010<jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> patients (all <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content><\/jats:italic>\u2009&lt;\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>As in <jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> patients, the <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content> is immediately responsive to <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content> in non\u2010<jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content> patients. Even in unselected chronic respiratory disease patients undergoing <jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>, the <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content> is a practical alternative to longer\u2010established health status questionnaires.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.12084","type":"journal-article","created":{"date-parts":[[2013,3,23]],"date-time":"2013-03-23T07:06:46Z","timestamp":1364022406000},"page":"974-977","source":"Crossref","is-referenced-by-count":24,"title":["Response of the <scp>COPD A<\/scp>ssessment <scp>T<\/scp>est to pulmonary rehabilitation in unselected chronic respiratory disease"],"prefix":"10.1111","volume":"18","author":[{"given":"Samantha S.C.","family":"Kon","sequence":"first","affiliation":[{"name":"NIHR Respiratory Biomedical Research Unit Royal Brompton &amp; Harefield NHS Foundation Trust  Middlesex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy L.","family":"Clark","sequence":"additional","affiliation":[{"name":"Harefield Pulmonary Rehabilitation Unit Royal Brompton &amp; Harefield NHS Foundation Trust  Middlesex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deniz","family":"Dilaver","sequence":"additional","affiliation":[{"name":"Harefield Pulmonary Rehabilitation Unit Royal Brompton &amp; Harefield NHS Foundation Trust  Middlesex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane L.","family":"Canavan","sequence":"additional","affiliation":[{"name":"NIHR Respiratory Biomedical Research Unit Royal Brompton &amp; Harefield NHS Foundation Trust  Middlesex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehul S.","family":"Patel","sequence":"additional","affiliation":[{"name":"NIHR Respiratory Biomedical Research Unit Royal Brompton &amp; Harefield NHS Foundation Trust  Middlesex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael I.","family":"Polkey","sequence":"additional","affiliation":[{"name":"NIHR Respiratory Biomedical Research Unit Royal Brompton &amp; Harefield NHS Foundation Trust  Middlesex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William D.\u2010C.","family":"Man","sequence":"additional","affiliation":[{"name":"NIHR Respiratory Biomedical Research Unit Royal Brompton &amp; Harefield NHS Foundation Trust  Middlesex UK"},{"name":"Harefield Pulmonary Rehabilitation Unit Royal Brompton &amp; Harefield NHS Foundation Trust  Middlesex UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,7,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00102509"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2010.156372"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-0309"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/15412555.2012.671869"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/15412555.2011.630248"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00177210"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2007.088070"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2004.028928"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000315142"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2010.04.025"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.42.10.773"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2012.02131.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.56.12.954"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003793.pub2"}],"container-title":["Respirology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fresp.12084","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/resp.12084","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T21:39:26Z","timestamp":1696196366000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/resp.12084"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,25]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1111\/resp.12084"],"URL":"https:\/\/doi.org\/10.1111\/resp.12084","archive":["Portico"],"relation":{},"ISSN":["1323-7799","1440-1843"],"issn-type":[{"value":"1323-7799","type":"print"},{"value":"1440-1843","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,25]]}}}