{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T20:43:52Z","timestamp":1785012232895,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,7,25]],"date-time":"2013-07-25T00:00:00Z","timestamp":1374710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and objective<\/jats:title><jats:p>Nocturnal application of continuous positive airway pressure (<jats:styled-content style=\"fixed-case\">CPAP<\/jats:styled-content>) is the standard treatment for patients with obstructive sleep apnoea (<jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>). Determination of the therapeutic pressure (<jats:styled-content style=\"fixed-case\">CPAP<\/jats:styled-content> titration) is usually performed by a technician in the sleep laboratory during attended polysomnography. One possible alternative to manual titration is automated titration. Indeed, during the last 15 years, devices have been developed that deliver autoadjustable <jats:styled-content style=\"fixed-case\">CPAP<\/jats:styled-content> (A\u2010<jats:styled-content style=\"fixed-case\">CPAP<\/jats:styled-content>). The aim of the present study was to compare the titration effectiveness of two A\u2010<jats:styled-content style=\"fixed-case\">CPAP<\/jats:styled-content> devices using different flow\u2010based algorithms in patients with <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a randomized study; 79 subjects underwent two consecutive unattended home A\u2010<jats:styled-content style=\"fixed-case\">CPAP<\/jats:styled-content> titration nights with two different devices (<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>utoset <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>esmed; <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>emstar <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>uto <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>espironics); during the third and the fourth night, patients underwent portable monitoring in the sleep laboratory during fixed <jats:styled-content style=\"fixed-case\">CPAP<\/jats:styled-content> at the <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">CPAP<\/jats:styled-content> recommended pressure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>land <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ltman plots showed good agreement between the recommended median and maximal pressure levels obtained with the two devices. A significant improvement was observed in all the sleep parameters by both <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">CPAP<\/jats:styled-content> machines to a similar degree.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>It was observed that the two <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">CPAP<\/jats:styled-content> devices using different algorithms are equally effective in initial titration of <jats:styled-content style=\"fixed-case\">CPAP<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.12098","type":"journal-article","created":{"date-parts":[[2013,4,19]],"date-time":"2013-04-19T08:12:51Z","timestamp":1366359171000},"page":"968-973","source":"Crossref","is-referenced-by-count":11,"title":["Titration effectiveness of two autoadjustable continuous positive airway pressure devices driven by different algorithms in patients with obstructive sleep apnoea"],"prefix":"10.1111","volume":"18","author":[{"given":"Mario Francesco","family":"Damiani","sequence":"first","affiliation":[{"name":"Institute of Respiratory Disease University of Bari  Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vitaliano Nicola","family":"Quaranta","sequence":"additional","affiliation":[{"name":"Institute of Respiratory Disease University of Bari  Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ersilia","family":"Tedeschi","sequence":"additional","affiliation":[{"name":"Institute of Respiratory Disease University of Bari  Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Drigo","sequence":"additional","affiliation":[{"name":"UOC of Pneumology Center of Sleep Breathing Medicine Hospital \u2018S. Maria del Prato\u2019  Feltre BL Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Ranieri","sequence":"additional","affiliation":[{"name":"Institute of Respiratory Disease University of Bari  Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierluigi","family":"Carrat\u00f9","sequence":"additional","affiliation":[{"name":"Institute of Respiratory Disease University of Bari  Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onofrio","family":"Resta","sequence":"additional","affiliation":[{"name":"Institute of Respiratory Disease University of Bari  Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,25]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(81)92140-1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.27133"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.97.10081720"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.98.12040753"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.97.10092073"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.154.3.8810613"},{"key":"e_1_2_6_8_1","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1155\/2006\/627096","article-title":"CTS Sleep Disordered Breathing Committee: Canadian Thoracic Society guidelines: diagnosis and treatment of sleep disordered breathing in adults","volume":"7","author":"Fleetham J","year":"2006","journal-title":"Can. 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