{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T13:35:57Z","timestamp":1770039357505,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,12,23]],"date-time":"2013-12-23T00:00:00Z","timestamp":1387756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2014,1]]},"abstract":"Abstract<\/jats:title>Background and objective<\/jats:title>Mesenteric fat is a type of intraperitoneal adipose tissue draining into portal circulation. The objective of this study was to investigate the relationships between mesenteric fat thickness and obstructive sleep apnoea (OSA<\/jats:styled-content>) in patients with suspected OSA<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods<\/jats:title>One hundred forty\u2010nine subjects (men: 114; women: 35) with suspected OSA<\/jats:styled-content> underwent ultrasound examinations of mesenteric, preperitoneal and subcutaneous fat thickness after overnight polysomnography. Body mass index (BMI<\/jats:styled-content>) and neck circumference were recorded.<\/jats:p><\/jats:sec>Results<\/jats:title>The subjects with OSA<\/jats:styled-content> (n<\/jats:italic>\u2009=\u2009130, apnoea\/hypopnoea index (AHI<\/jats:styled-content>) >5\/h) had greater neck circumference, higher BMI<\/jats:styled-content>, and greater mesenteric and preperitoneal fat thickness than those without OSA<\/jats:styled-content> (n<\/jats:italic>\u2009=\u200919, AHI<\/jats:styled-content>\u2009\u2264\u20095\/h). There was positive correlation of AHI<\/jats:styled-content> with mesenteric (r\u2009=\u20090.43, P<\/jats:styled-content><\/jats:italic>\u2009<\u20090.001) and preperitoneal fat thickness (r\u2009=\u20090.3, P<\/jats:styled-content><\/jats:italic>\u2009<\u20090.001), whereas no significant association was observed between AHI<\/jats:styled-content> and subcutaneous fat thickness (r\u2009=\u20090.09, P<\/jats:styled-content><\/jats:italic>\u2009=\u20090.27). On multivariate logistic regression, after adjustments for gender, age, BMI<\/jats:styled-content>, neck circumference, and preperitoneal and subcutaneous fat thickness, the mesenteric fat thickness had a positive association with the presence of moderate OSA<\/jats:styled-content> and severe OSA<\/jats:styled-content>, with odds ratios of 7.18 and 7.45 for every 1\u2009cm increase in mesenteric fat thickness when AHI<\/jats:styled-content> was defined as \u226515\/h and AHI<\/jats:styled-content>\u2009\u2265\u200930\/h, respectively.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Mesenteric fat thickness is associated with increased risk of OSA<\/jats:styled-content>, independent of other abdominal fat thickness, BMI<\/jats:styled-content> and neck circumference. Sonographic measurement is potentially a useful tool for further evaluating the complex association of visceral fat, metabolic syndrome and OSA<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.12164","type":"journal-article","created":{"date-parts":[[2013,8,8]],"date-time":"2013-08-08T15:34:52Z","timestamp":1375976092000},"page":"92-97","source":"Crossref","is-referenced-by-count":30,"title":["Mesenteric fat thickness is associated with increased risk of obstructive sleep apnoea"],"prefix":"10.1111","volume":"19","author":[{"given":"Kin Hung","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Imaging and Interventional Radiology The Prince of Wales Hospital The Chinese University of Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Winnie C.W.","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Imaging and Interventional Radiology The Prince of Wales Hospital The Chinese University of Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kin Wang","family":"To","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics The Prince of Wales Hospital The Chinese University of Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fanny W.S.","family":"Ko","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics The Prince of Wales Hospital The Chinese University of Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanna S.S.","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics The Prince of Wales Hospital The Chinese University of Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenny C.L.","family":"Ngai","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics The Prince of Wales Hospital The Chinese University of Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeff Wai Sang","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Imaging and Interventional Radiology The Prince of Wales Hospital The Chinese University of Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil T.","family":"Ahuja","sequence":"additional","affiliation":[{"name":"Department of Imaging and Interventional Radiology The Prince of Wales Hospital The Chinese University of Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David S.C.","family":"Hui","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics The Prince of Wales Hospital The Chinese University of Hong Kong Hong 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