{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T05:10:54Z","timestamp":1716441054657},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,12,23]],"date-time":"2013-12-23T00:00:00Z","timestamp":1387756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2014,1]]},"abstract":"Abstract<\/jats:title>Background and objective<\/jats:title>Continuous positive airway pressure (CPAP<\/jats:styled-content>) has been used to treat patients with chronic heart failure (CHF<\/jats:styled-content>) and sleep\u2010disordered breathing (SDB<\/jats:styled-content>). CPAP<\/jats:styled-content> treatment in severe CHF<\/jats:styled-content> with concomitant SDB<\/jats:styled-content> and atrial fibrillation has been linked to impairment of cardiac output (CO<\/jats:styled-content>) as a potential cause for adverse outcome. The aim of the present study was to test whether incremental CPAP<\/jats:styled-content> application in awake CHF<\/jats:styled-content> patients with SDB<\/jats:styled-content>, with and without atrial fibrillation, induces acute alterations of blood pressure (BP<\/jats:styled-content>), heart rate (HR<\/jats:styled-content>) and CO<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods<\/jats:title>During daytime, we applied incremental CPAP<\/jats:styled-content> (4\u201310\u2009cmH2<\/jats:sub>O<\/jats:roman><\/jats:styled-content>) in 37 stable patients with CHF<\/jats:styled-content> and SDB<\/jats:styled-content>. BP<\/jats:styled-content> and HR<\/jats:styled-content> were assessed after each 1\u2009cmH2<\/jats:sub>O<\/jats:roman> CPAP<\/jats:styled-content> increase in 5\u2010min intervals in the entire sample, and CO<\/jats:styled-content> was assessed at one centre (n<\/jats:styled-content><\/jats:italic>\u2009=\u200911).<\/jats:p><\/jats:sec>Results<\/jats:title>Neither mean BP<\/jats:styled-content>, HR<\/jats:styled-content> nor CO<\/jats:styled-content> changed significantly with incremental CPAP<\/jats:styled-content> (at 0 and 10\u2009cmH2<\/jats:sub>O<\/jats:roman><\/jats:styled-content>: 85\u2009\u00b1\u20092 and 84\u2009\u00b1\u20092\u2009mm\u2009H<\/jats:styled-content>g, P<\/jats:styled-content><\/jats:italic>\u2009=\u20091.0, 63\u2009\u00b1\u20091 to 61\u2009\u00b1\u20092\u2009b.p.m., P<\/jats:styled-content><\/jats:italic>\u2009=\u20090.88 and 2.03\u2009\u00b1\u20090.5 and 2.35\u2009\u00b1\u20090.8\u2009L\/min\/m2<\/jats:sup>, P<\/jats:styled-content><\/jats:italic>\u2009=\u20090.92, respectively). No significant differences in maximum BP<\/jats:styled-content> drop or HR<\/jats:styled-content> drop between patients with sinus rhythm and atrial fibrillation were found. In 1 of 37 patients, a prespecified event of haemodynamic compromise (drop of mean BP<\/jats:styled-content> >15\u2009mm\u2009Hg) without clinical signs occurred.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>These results contribute to the evidence that CPAP<\/jats:styled-content> does not cause haemodynamic compromise in the vast majority of normotensive CHF<\/jats:styled-content> patients with SDB<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.12193","type":"journal-article","created":{"date-parts":[[2013,10,8]],"date-time":"2013-10-08T15:20:51Z","timestamp":1381245651000},"page":"47-52","source":"Crossref","is-referenced-by-count":10,"title":["Acute haemodynamic effects of continuous positive airway pressure in awake patients with heart failure"],"prefix":"10.1111","volume":"19","author":[{"given":"Stephan","family":"Schroll","sequence":"first","affiliation":[{"name":"Department of Internal Medicine II Pneumology University Hospital Regensburg Regensburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fr\u00e9d\u00e9ric","family":"S\u00e9ri\u00e8s","sequence":"additional","affiliation":[{"name":"Research Centre IUCPQ Universit\u00e9 Laval Qu\u00e9bec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keir","family":"Lewis","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Prince Phillip Hospital Swansea College of Medicine Llanelli Wales UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Benjamin","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Prince Phillip Hospital Swansea College of Medicine Llanelli Wales UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Escourrou","sequence":"additional","affiliation":[{"name":"Centre for Sleep Medicine H\u00f4pital Antoine B\u00e9cl\u00e8re Clamart France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Luigart","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II Pneumology University Hospital Regensburg Regensburg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Pfeifer","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II Pneumology University Hospital Regensburg Regensburg"},{"name":"Centre for Pneumology Donaustauf Hospital Donaustauf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Arzt","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II Pneumology University Hospital Regensburg Regensburg"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,12,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfp057"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.97.21.2154"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00037106"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200306-752OC"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.109.868786"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.01.084"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfq183"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejheart.2008.08.005"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa051001"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.53.11.957"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.95.08030430"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/145.2_Pt_1.377"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1042\/cs0880173"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000150442"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-011-0571-4"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.19.2336"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.21.2269"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000229661.06235.08"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2005.06.001"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000029355"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0066-782X2007000100016"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0828-282X(08)70668-8"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2869.2008.00701.x"}],"container-title":["Respirology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fresp.12193","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/resp.12193","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T18:18:25Z","timestamp":1696184305000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/resp.12193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,23]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.1111\/resp.12193"],"URL":"https:\/\/doi.org\/10.1111\/resp.12193","archive":["Portico"],"relation":{},"ISSN":["1323-7799","1440-1843"],"issn-type":[{"value":"1323-7799","type":"print"},{"value":"1440-1843","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,23]]}}}