{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T16:52:51Z","timestamp":1780851171082,"version":"3.54.1"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,10,7]],"date-time":"2014-10-07T00:00:00Z","timestamp":1412640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2015,1]]},"abstract":"Abstract<\/jats:title>Background and objective<\/jats:title>Although pulmonary arteriovenous malformations (PAVMs<\/jats:styled-content>) are rare, they are important in clinical practice because they are associated with life\u2010threatening complications such as brain abscess, stroke and lung haemorrhage. The aims of the present study were to characterize PAVMs<\/jats:styled-content> in a K<\/jats:styled-content>orean population and to examine the incidence and factors associated with cerebral complications, which are a major cause of mortality.<\/jats:p><\/jats:sec>Methods<\/jats:title>The medical records of patients with PAVMs<\/jats:styled-content> between 2000 and 2013 were retrospectively reviewed. PAVMs<\/jats:styled-content> were confirmed by enhanced chest computed tomography or by pulmonary angiography.<\/jats:p><\/jats:sec>Results<\/jats:title>Ninety patients (median age, 47.5 years; 81.8% female) with PAVMs<\/jats:styled-content> were included. Twelve patients (13.3%) were clinically diagnosed with hereditary haemorrhagic telangiectasia (HHT<\/jats:styled-content>) according to the C<\/jats:styled-content>uracao criteria. Sixty\u2010three patients underwent transcatheter embolization with no severe adverse events. Three patients required retreatment during a mean follow\u2010up period of 3.3 years. Six and 14 patients suffered brain abscess or stroke, respectively, as a complication of PAVMs<\/jats:styled-content>. These complications were not associated with the diameter of the arteries feeding the PAVMs<\/jats:styled-content> (odds ratio, 1.106; 95% confidence interval, 0.895\u20131.366; P<\/jats:italic>\u2009=\u20090.352)<\/jats:p><\/jats:sec>Conclusions<\/jats:title>PAVMs<\/jats:styled-content> are less associated with HHT<\/jats:styled-content> in K<\/jats:styled-content>oreans than in W<\/jats:styled-content>estern populations. Transcatheter embolization of PAVMs<\/jats:styled-content> is safe and effective, and physicians need to consider treating the small arteries feeding PAVMs<\/jats:styled-content> to prevent cerebral complications.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.12411","type":"journal-article","created":{"date-parts":[[2014,10,7]],"date-time":"2014-10-07T10:21:00Z","timestamp":1412677260000},"page":"155-159","source":"Crossref","is-referenced-by-count":14,"title":["Clinical characteristics of pulmonary arteriovenous malformations in K<\/scp>oreans"],"prefix":"10.1111","volume":"20","author":[{"given":"Hyun\u2010Jung","family":"Kim","sequence":"first","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine Department of Internal Medicine College of Medicine University of Ulsan Asan Medical Center Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae\u2010Seung","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine Department of Internal Medicine College of Medicine University of Ulsan Asan Medical Center Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeon\u2010Mok","family":"Oh","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine Department of Internal Medicine College of Medicine University of Ulsan Asan Medical Center Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae\u2010Sun","family":"Shim","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine Department of Internal Medicine College of Medicine University of Ulsan Asan Medical Center Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chae\u2010Man","family":"Lim","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine Department of Internal Medicine College of Medicine University of Ulsan Asan Medical Center Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youn\u2010Suck","family":"Koh","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine Department of Internal Medicine College of Medicine University of Ulsan Asan Medical Center Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woo\u2010Sung","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine Department of Internal Medicine College of Medicine University of Ulsan Asan Medical Center Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang\u2010Do","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine Department of Internal Medicine College of Medicine University of Ulsan Asan Medical Center Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,7]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2002.17.3.407"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2796.2000.00725.x"},{"key":"e_1_2_5_4_1","first-page":"600","article-title":"Massive hemoptysis in pregnancy due to a solitary pulmonary arteriovenous malformation","volume":"161","author":"Bradshaw D","year":"1994","journal-title":"West. 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