{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:41:40Z","timestamp":1777927300647,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,10,19]],"date-time":"2014-10-19T00:00:00Z","timestamp":1413676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","award":["UL1 RR025780"],"award-info":[{"award-number":["UL1 RR025780"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Institute of Health","award":["HL 089856"],"award-info":[{"award-number":["HL 089856"]}]},{"name":"National Institute of Health","award":["HL 089897"],"award-info":[{"award-number":["HL 089897"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and objective<\/jats:title><jats:p>Menthol cigarettes contain higher levels of menthol to produce a characteristic mint flavour and cooling sensation. Compared with non\u2010menthol cigarettes, little information exists on the effects of menthol cigarette smoking on clinical and radiological characteristics of chronic obstructive pulmonary disease (<jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content>). The main objective of the present study was to examine associations between menthol cigarette use and the risk of<jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content>and its characteristics, such as exacerbation, comorbidities and computed tomography (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) abnormalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analysed the data from 5699 current smokers in the COPDGene cohort to evaluate whether lung function, comorbidities, exacerbations and<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>parameters were different between menthol and non\u2010menthol cigarette smokers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 3758 (65.9%) who reported use of menthol cigarettes. Multivariable regression analysis revealed that younger age, female gender and African\u2010American ethnicity were significantly associated with smoking of menthol cigarettes. No significant associations were found between menthol cigarette use and<jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content>, major<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>findings or comorbidities, such as cardiovascular disease, congestive heart failure, peripheral vascular disease, cerebrovascular disease, hypertension, diabetes, gastro\u2010oesophageal reflux and osteoporosis; however, menthol cigarette smokers were more likely to experience a severe exacerbation of<jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content>during longitudinal follow\u2010up (odds ratio 1.29; 95% confidence interval: 1.01\u20131.54) compared with the non\u2010menthol cigarette smokers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These results confirm that menthol cigarettes are not safer than traditional cigarettes and suggest that menthol cigarette smokers may have more frequent severe exacerbations than non\u2010menthol cigarette smokers.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.12421","type":"journal-article","created":{"date-parts":[[2014,10,20]],"date-time":"2014-10-20T02:01:47Z","timestamp":1413770507000},"page":"108-114","source":"Crossref","is-referenced-by-count":16,"title":["Menthol cigarette smoking in the<scp>COPDG<\/scp>ene cohort: Relationship with<scp>COPD<\/scp>, comorbidities and<scp>CT<\/scp>metrics"],"prefix":"10.1111","volume":"20","author":[{"given":"Seoung Ju","family":"Park","sequence":"first","affiliation":[{"name":"Department of Medicine National Jewish Health Denver Colorado USA"},{"name":"Department of Internal Medicine and Research Institute of Clinical Medicine\u2010Biomedical Research Institute of Chonbuk National University Hospital Chonbuk National University Jeonju South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marilyn G.","family":"Foreman","sequence":"additional","affiliation":[{"name":"Pulmonary and Critical Care Division Morehouse School of Medicine Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawn L.","family":"Demeo","sequence":"additional","affiliation":[{"name":"Channing Division of Network Medicine and Division of Pulmonary and Critical Care Medicine Brigham and Women's Hospital and Harvard Medical School Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surya P.","family":"Bhatt","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Allergy and Critical Care Medicine University of Alabama at Birmingham Birmingham Alabama USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia N.","family":"Hansel","sequence":"additional","affiliation":[{"name":"Department of Medicine Johns Hopkins University School of Medicine Baltimore Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A.","family":"Wise","sequence":"additional","affiliation":[{"name":"Department of Medicine Johns Hopkins University School of Medicine Baltimore Maryland USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Soler","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine University of California San Diego California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Russell P.","family":"Bowler","sequence":"additional","affiliation":[{"name":"Department of Medicine National Jewish Health Denver Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,10,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwg182"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2466-11-18"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2012.320"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yrtph.2006.09.004"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"ii49","DOI":"10.1136\/tc.2010.041947","article-title":"Menthol cigarettes and smoking cessation behaviour: a review of tobacco industry documents","volume":"20","author":"Anderson SJ","year":"2011","journal-title":"Tob. Control"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/14622200601078418"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/14622203710001649696"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/tc.11.2.135"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2011.06.039"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.2010.03203.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yrtph.2012.03.002"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-1252"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00021707"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00128008"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/15412550903499522"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/15412555.2012.690010"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.11110173"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/1617-9625-9-S1-S1"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/14622200701239647"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0376-8716(96)01331-2"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/1617-9625-10-19"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.161.2.9901044"},{"key":"e_1_2_7_24_1","first-page":"1035","article-title":"Response of human ciliated respiratory cells to a mixture of menthol, eucalyptus oil and pine needle oil","volume":"47","author":"Riechelmann H","year":"1997","journal-title":"Arzneimittelforschung"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/14622200310001649469"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200801-059OC"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/1465-9921-14-59"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200907-1008OC"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/RTI.0b013e318298733c"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2011-201185"}],"container-title":["Respirology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fresp.12421","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/resp.12421","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T03:10:00Z","timestamp":1717470600000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/resp.12421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,19]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1111\/resp.12421"],"URL":"https:\/\/doi.org\/10.1111\/resp.12421","archive":["Portico"],"relation":{},"ISSN":["1323-7799","1440-1843"],"issn-type":[{"value":"1323-7799","type":"print"},{"value":"1440-1843","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,19]]}}}