{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T15:27:49Z","timestamp":1788881269666,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,1,26]],"date-time":"2015-01-26T00:00:00Z","timestamp":1422230400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Chungnam National University Hospital, Daejeon, Korea"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2015,4]]},"abstract":"Abstract<\/jats:title>Background and objective<\/jats:title>Incidence and predictors of endobronchial tuberculosis (EBTB<\/jats:styled-content>) remain unknown because of the lack of prospective studies. Our objective was to assess the incidence and predictors of concomitant EBTB<\/jats:styled-content> in patients with active pulmonary tuberculosis (PTB<\/jats:styled-content>).<\/jats:p><\/jats:sec>Methods<\/jats:title>We prospectively performed routine bronchoscopic examination in all patients with PTB<\/jats:styled-content> to detect EBTB<\/jats:styled-content>. Clinical and bronchoscopic findings were analyzed to elucidate predictors of EBTB<\/jats:styled-content>.<\/jats:p><\/jats:sec>Results<\/jats:title>Bronchoscopies of 429 PTB<\/jats:styled-content> patients were performed at a tertiary referral hospital in K<\/jats:styled-content>orea. Among those, 233 patients (54.3%) had EBTB<\/jats:styled-content>. Female gender (odds ratio (OR<\/jats:styled-content>) 4.35, 95% confidence interval (CI<\/jats:styled-content>) 1.78\u201310.63), longer symptom duration (>4 weeks; OR<\/jats:styled-content> 1.86, 95% CI<\/jats:styled-content> 1.05\u20135.46), and no previous history of tuberculosis (OR<\/jats:styled-content> 4.16, 95% CI<\/jats:styled-content> 1.22\u201314.18) were found to be the independent predictors of concomitant EBTB in patients with active PTB<\/jats:styled-content>. Most of the EBTB<\/jats:styled-content>\/PTB<\/jats:styled-content> patients had mild stenosis, and more than 20% of them had severe stenosis at the time of diagnosis. Patients with EBTB<\/jats:styled-content> had follow\u2010up bronchoscopy to evaluate persistent airway stenosis. Persistent bronchostenosis with the lumen narrowed by more than one third occurred in 20.7% (30\/145) of patients. The involvement length and decreased forced expiratory volume in 1\u2009s were the risk factors for persistent bronchostenosis.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>In patients with active PTB<\/jats:styled-content>, 50% or more have EBTB<\/jats:styled-content>. Female gender and longer duration of symptoms are the main predictors of concomitant EBTB<\/jats:styled-content>. Immediate diagnostic bronchoscopy in patients with active PTB<\/jats:styled-content> should be considered in selected patients for detection of brocnhostenosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.12474","type":"journal-article","created":{"date-parts":[[2015,1,26]],"date-time":"2015-01-26T06:15:53Z","timestamp":1422252953000},"page":"488-495","source":"Crossref","is-referenced-by-count":77,"title":["Incidence and clinical predictors of endobronchial tuberculosis in patients with pulmonary tuberculosis"],"prefix":"10.1111","volume":"20","author":[{"given":"Sung\u2010Soo","family":"Jung","sequence":"first","affiliation":[{"name":"Division of Respiratory and Critical Care Medicine Department of Internal Medicine Chungnam National University Hospital Daejeon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee\u2010Sun","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Respiratory and Critical Care Medicine Department of Internal Medicine Chungnam National University Hospital Daejeon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju\u2010Ock","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Respiratory and Critical Care Medicine Department of Internal Medicine Chungnam National University Hospital Daejeon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun\u2010Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Respiratory and Critical Care Medicine Department of Internal Medicine Chungnam National University Hospital Daejeon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,26]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0366-0869(51)80003-0"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.1996.tb00017.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.117.2.385"},{"key":"e_1_2_7_5_1","first-page":"57","article-title":"Predictors of persistent airway stenosis in patients with endobronchial tuberculosis","volume":"11","author":"Um SW","year":"2007","journal-title":"Int. J. Tuberc. Lung Dis."},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/2049-6958-7-34"},{"key":"e_1_2_7_7_1","unstructured":"National Tuberculosis Association of USA.Diagnostic Standards and Classification of Tuberculosis.NTA New York 1961."},{"key":"e_1_2_7_8_1","first-page":"247","article-title":"Endobronchial tuberculosis","volume":"45","author":"Surender K","year":"2003","journal-title":"Indian J. Chest Dis. Allied Sci."},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.159.5.1414809"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-193704000-00011"},{"key":"e_1_2_7_11_1","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/S0096-5588(20)31369-6","article-title":"Tuberculous tracheobronchitis","volume":"16","author":"Judd AR","year":"1947","journal-title":"J. Thorac. Surg."},{"key":"e_1_2_7_12_1","first-page":"604","article-title":"Tuberculosis of trachea and major bronchi","volume":"60","author":"Auerbach O","year":"1949","journal-title":"Am. Rev. Tuberc."},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.64.4.537"},{"key":"e_1_2_7_14_1","first-page":"657","article-title":"Bronchial disease in lungs for pulmonary tuberculosis","volume":"68","author":"Olsen DE","year":"1953","journal-title":"Am. Rev. Tuberc."},{"key":"e_1_2_7_15_1","first-page":"727","article-title":"Endobronchial tuberculosis revisited","volume":"89","author":"Marry SM","year":"1987","journal-title":"Chest"},{"key":"e_1_2_7_16_1","first-page":"789","article-title":"Tracheobronchoplasty for endobronchial tuberculosis","volume":"66","author":"Nakamoto K","year":"1991","journal-title":"Kekkaku"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.31.593"},{"key":"e_1_2_7_18_1","first-page":"558","article-title":"Diagnostic features and therapeutic outcome of erosive and ulcerous endobronchial tuberculosis","volume":"2","author":"Rikimaru T","year":"1998","journal-title":"Int. J. Tuberc. Lung Dis."},{"key":"e_1_2_7_19_1","first-page":"347","article-title":"Clinical investigation on endobronchial tuberculosis","volume":"74","author":"Toyota E","year":"1999","journal-title":"Kekkaku"},{"key":"e_1_2_7_20_1","first-page":"351","article-title":"Natural history of tuberculous tracheobronchitis","volume":"47","author":"Sakin O","year":"1943","journal-title":"Am. Rev. Tuberc."},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2000.00285.x"},{"key":"e_1_2_7_22_1","first-page":"1046","article-title":"Recovery rate of NTM from AFB smear\u2010positive sputum specimens at a medical centre in South Korea","volume":"9","author":"Jeon K","year":"2005","journal-title":"Int. J. Tuberc. Lung Dis."},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.3947\/ic.2013.45.1.99"}],"container-title":["Respirology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fresp.12474","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/resp.12474","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/resp.12474","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/resp.12474","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T16:21:19Z","timestamp":1695572479000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/resp.12474"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,26]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1111\/resp.12474"],"URL":"https:\/\/doi.org\/10.1111\/resp.12474","archive":["Portico"],"relation":{},"ISSN":["1323-7799","1440-1843"],"issn-type":[{"value":"1323-7799","type":"print"},{"value":"1440-1843","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,26]]}}}