{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T17:04:25Z","timestamp":1789405465893,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,2,27]],"date-time":"2015-02-27T00:00:00Z","timestamp":1424995200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and objective<\/jats:title><jats:p>Physical activity is an important parameter in patients with chronic obstructive pulmonary disease, but has not been studied in detail in patients with interstitial lung disease. This study aimed to evaluate physical activity in patients with idiopathic pulmonary fibrosis (<jats:styled-content style=\"fixed-case\">IPF<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Physical activity was monitored in 31 stable <jats:styled-content style=\"fixed-case\">IPF<\/jats:styled-content> patients using an accelerometer for 1 month. The following factors reflecting physical activity were measured: the number of steps, walking distance, the time spent at magnitude of movement (<jats:styled-content style=\"fixed-case\">MM<\/jats:styled-content>) 1\u20136, physical activity\u2010related energy expenditure (<jats:styled-content style=\"fixed-case\">PAEE<\/jats:styled-content>) and total energy expenditure. We also measured the following clinical parameters: the modified Medical Research Council (<jats:styled-content style=\"fixed-case\">MRC<\/jats:styled-content>) scale, <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>rebs von den <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>ungen\u20106 (<jats:styled-content style=\"fixed-case\">KL<\/jats:styled-content>\u20106), pulmonary function parameters, 6\u2010min walk test (6<jats:styled-content style=\"fixed-case\">MWT<\/jats:styled-content>) results and high\u2010resolution computed tomography (<jats:styled-content style=\"fixed-case\">HRCT<\/jats:styled-content>) findings of the chest. We determined the relationship between these parameters and physical activity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We recorded 24 days of physical activity data. The time spent at <jats:styled-content style=\"fixed-case\">MM<\/jats:styled-content>\u2009&lt;\u20091 was more than 10\u2009h per day, whereas that at <jats:styled-content style=\"fixed-case\">MM<\/jats:styled-content>\u2009&gt;\u20091 was approximately 1\u2009h per day. The modified <jats:styled-content style=\"fixed-case\">MRC<\/jats:styled-content> scale, serum <jats:styled-content style=\"fixed-case\">KL<\/jats:styled-content>\u20106 levels, 6<jats:styled-content style=\"fixed-case\">MWT<\/jats:styled-content> distance, and the extent of honeycomb and reticular abnormality on <jats:styled-content style=\"fixed-case\">HRCT<\/jats:styled-content> were associated with several facets of physical activity. In particular, lower <jats:styled-content style=\"fixed-case\">KL<\/jats:styled-content>\u20106 levels were correlated with higher physical activity based on the number of steps, walking distance, the time spent at <jats:styled-content style=\"fixed-case\">MM<\/jats:styled-content> 1\u20134 and <jats:styled-content style=\"fixed-case\">PAEE<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The modified <jats:styled-content style=\"fixed-case\">MRC<\/jats:styled-content> scale, 6<jats:styled-content style=\"fixed-case\">MWT<\/jats:styled-content> distance, extent of fibrosis on <jats:styled-content style=\"fixed-case\">HRCT<\/jats:styled-content> and serum <jats:styled-content style=\"fixed-case\">KL<\/jats:styled-content>\u20106 levels are strongly associated with physical activity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.12500","type":"journal-article","created":{"date-parts":[[2015,2,27]],"date-time":"2015-02-27T09:14:42Z","timestamp":1425028482000},"page":"640-646","source":"Crossref","is-referenced-by-count":50,"title":["Physical activity in patients with idiopathic pulmonary fibrosis"],"prefix":"10.1111","volume":"20","author":[{"given":"Masayuki","family":"Nakayama","sequence":"first","affiliation":[{"name":"Division of Pulmonary Medicine, Department of Medicine Jichi Medical University  Shimotsuke Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masashi","family":"Bando","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine, Department of Medicine Jichi Medical University  Shimotsuke Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Araki","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Jichi Medical University  Shimotsuke Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshie","family":"Sekine","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Jichi Medical University  Shimotsuke Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumio","family":"Kurosaki","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine, Department of Medicine Jichi Medical University  Shimotsuke Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuro","family":"Sawata","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine, Department of Medicine Jichi Medical University  Shimotsuke Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoko","family":"Nakazawa","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine, Department of Medicine Jichi Medical University  Shimotsuke Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoko","family":"Mato","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine, Department of Medicine Jichi Medical University  Shimotsuke Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Yamasawa","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine, Department of Medicine Jichi Medical University  Shimotsuke Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukihiko","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine, Department of Medicine Jichi Medical University  Shimotsuke Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,2,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00024608"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-2521"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2014"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2009-040GL"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00034805"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00034905"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00035005"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.166.1.at1102"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1079\/BJN20031033"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/HCR.0b013e3181e175f2"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000330046"},{"key":"e_1_2_6_13_1","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1164\/rccm.201307-1240OC","article-title":"Risk factors and comorbidities in the preclinical stages of chronic obstructive pulmonary disease","volume":"189","author":"Van Remoortel H","year":"2014","journal-title":"Am. 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