{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T04:19:26Z","timestamp":1790482766608,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,7,2]],"date-time":"2015-07-02T00:00:00Z","timestamp":1435795200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"AGIR \u00e0 dom. Association"},{"name":"Fonds AGIR pour les Maladies Chroniques"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2015,10]]},"abstract":"Abstract<\/jats:title>Background and objective<\/jats:title>During continuous positive airway pressure (CPAP<\/jats:styled-content>) treatment, some patients with obstructive sleep apnoea syndrome (OSAS<\/jats:styled-content>) require an oronasal mask (ONM<\/jats:styled-content>) to prevent excessive mouth leakage. Factors contributing to sleep\u2010related mouth opening under CPAP<\/jats:styled-content> treatment remain known. We compared mouth opening during sleep in patients treated with CPAP<\/jats:styled-content> by nasal mask (NM<\/jats:styled-content>) versus ONM<\/jats:styled-content>.<\/jats:p><\/jats:sec>Methods<\/jats:title>Cross\u2010sectional prospective study: patients treated with CPAP<\/jats:styled-content> for at least 4 months underwent a sleep recording using a type 4 monitoring device (B<\/jats:styled-content>rizzy\u2010N<\/jats:styled-content>omics) that records mouth opening via a magnetometric distance meter. Clinical assessment included anthropometry, smoking status and the M<\/jats:styled-content>allampati score. Nasal obstruction was assessed by the N<\/jats:styled-content>asal O<\/jats:styled-content>bstruction S<\/jats:styled-content>ymptom E<\/jats:styled-content>valuation questionnaire.<\/jats:p><\/jats:sec>Results<\/jats:title>Thirty\u2010eight patients were included, 34 analysed (22 men; age\u2009=\u200957.4 (53; 62) years; body mass index\u2009=\u200932.6 (29.1; 35.2) kg\/m2<\/jats:sup>; median (25th; 75th)). Twenty\u2010seven patients were treated with NM<\/jats:styled-content> and seven with ONM<\/jats:styled-content>. Patients with ONM<\/jats:styled-content> were more often active smokers and trended to have greater nasal obstruction and lower forced expiratory volume in 1 s. They also exhibited a greater mouth opening during sleep (median (25th;75th)\u2009=\u200913.0 (11.0; 15.0) vs 6.0 (5.0; 10.0) mm, P<\/jats:italic><\/jats:styled-content>\u2009<\u20090.001) and a higher oxygen desaturation index (9.5 (6.2; 15.5) vs 2.9 (1.0; 6.1) events\/h, P<\/jats:italic><\/jats:styled-content>\u2009=\u20090.009). In multivariate analysis, male gender and nasal obstruction were independently associated with mouth opening under ONM CPAP<\/jats:styled-content> treatment.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>After several months of CPAP<\/jats:styled-content> treatment, some patients using ONM<\/jats:styled-content> persist in keeping their mouths open at night. Nasal obstruction and male gender contribute to this phenomenon.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.12584","type":"journal-article","created":{"date-parts":[[2015,7,3]],"date-time":"2015-07-03T17:51:52Z","timestamp":1435945912000},"page":"1123-1130","source":"Crossref","is-referenced-by-count":36,"title":["Nasal obstruction and male gender contribute to the persistence of mouth opening during sleep in CPAP<\/scp>\u2010treated obstructive sleep apnoea"],"prefix":"10.1111","volume":"20","author":[{"given":"Marius","family":"Lebret","sequence":"first","affiliation":[{"name":"University Pierre and Marie Curie\u2010Paris VI Paris France"},{"name":"AGIR \u00e0 dom. Association La Tronche France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Arnol","sequence":"additional","affiliation":[{"name":"AGIR \u00e0 dom. Association La Tronche France"},{"name":"HP2 laboratory INSERM U1042 University Grenoble Alpes Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Contal","sequence":"additional","affiliation":[{"name":"University of Health Sciences (HESAV) University of Applied Sciences and Arts of Western Switzerland (HES\u2010SO) Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Beno\u00eet","family":"Martinot","sequence":"additional","affiliation":[{"name":"Department of Pneumology St Elisabeth Hospital Namur Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renaud","family":"Tamisier","sequence":"additional","affiliation":[{"name":"HP2 laboratory INSERM U1042 University Grenoble Alpes Grenoble France"},{"name":"Department of Physiology and Sleep Albert Michallon Hospital Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Louis","family":"Pepin","sequence":"additional","affiliation":[{"name":"HP2 laboratory INSERM U1042 University Grenoble Alpes Grenoble France"},{"name":"Department of Physiology and Sleep Albert Michallon Hospital Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Christian","family":"Borel","sequence":"additional","affiliation":[{"name":"AGIR \u00e0 dom. 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