{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T12:28:34Z","timestamp":1789648114655,"version":"4.0.0"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,6,2]],"date-time":"2016-06-02T00:00:00Z","timestamp":1464825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2016,8]]},"abstract":"Abstract<\/jats:title>Background and objective<\/jats:title>Transbronchial cryobiopsy (TBCB) is a technique in which frozen samples of lung are obtained using a probe inserted through a bronchoscope. We performed a retrospective study to assess the performance of the TBCB procedure complemented by segmental bronchial blockade using an angioplasty balloon, in terms of diagnostic yield and safety in diffuse parenchymal lung disease (DPLD).<\/jats:p><\/jats:sec>Methods<\/jats:title>Data from 100 patients with suspected DPLD (clinical and radiological findings), who underwent TBCB in our institution to establish a definitive diagnosis, were reviewed. In our institution, TBCB is monitored with fluoroscopy and performed under general anaesthesia by a multidisciplinary team (an anaesthesiologist, a pulmonologist and an interventional radiologist). In each patient, four samples were collected using a 2.4\u2010mm distal diameter cryoprobe. To control bleeding, the biopsied segmental bronchus was blocked with a 6\u2010mm diameter angioplasty balloon, inserted over a 0.035\u2010inch angled hydrophilic guidewire. After the cryoextraction, the balloon was inflated for 3\u2009min intervals until bleeding stopped.<\/jats:p><\/jats:sec>Results<\/jats:title>Overall, 98% of samples had diagnostic value. In 85% of cases, DPLD was confirmed, while in 7%, cancer was diagnosed. Complications were observed in 16% of the patients: 13 patients developed moderate haemorrhage, and 3 developed pneumothorax.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Transbronchial cryobiopsy had a high diagnostic yield for DPLD. Performing the procedure under fluoroscopy guidance and using angioplasty balloon for selective bronchial blockade achieved a low rate of iatrogenic complications directly associated with the technique.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.12827","type":"journal-article","created":{"date-parts":[[2016,6,2]],"date-time":"2016-06-02T13:20:36Z","timestamp":1464873636000},"page":"1094-1099","source":"Crossref","is-referenced-by-count":46,"title":["Usefulness of an angioplasty balloon as selective bronchial blockade device after transbronchial cryobiopsy"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1399-7447","authenticated-orcid":false,"given":"Jos\u00e9 Javier","family":"Echevarria\u2010Uraga","sequence":"first","affiliation":[{"name":"Department of Radiology Hospital Galdakao Usansolo Basque Country Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio","family":"P\u00e9rez\u2010Izquierdo","sequence":"additional","affiliation":[{"name":"Department of Pulmonology Hospital Galdakao Usansolo Basque Country Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nerea","family":"Garc\u00eda\u2010Garai","sequence":"additional","affiliation":[{"name":"Department of Radiology Hospital Galdakao Usansolo Basque Country Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Est\u00edbaliz","family":"G\u00f3mez\u2010Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Department of Radiology Hospital Galdakao Usansolo Basque Country Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amaia","family":"Aramburu\u2010Ojembarrena","sequence":"additional","affiliation":[{"name":"Department of Pulmonology Hospital Galdakao Usansolo Basque Country Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Tena\u2010Tudanca","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Hospital Galdakao Usansolo Basque Country Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 L.","family":"Migu\u00e9lez\u2010Vidales","sequence":"additional","affiliation":[{"name":"Department of Radiology Hospital Galdakao Usansolo Basque Country Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Capelastegui\u2010Saiz","sequence":"additional","affiliation":[{"name":"Department of Pulmonology Hospital Galdakao Usansolo Basque Country Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,6,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201308-1483ST"},{"key":"e_1_2_6_3_1","first-page":"747","article-title":"A prospective cooperative study of complications following flexible fiberoptic bronchoscopy","volume":"69","author":"Pereira W","year":"1976","journal-title":"Chest"},{"key":"e_1_2_6_4_1","first-page":"708","article-title":"Deaths and complications associated with transbronchial lung biopsy","volume":"115","author":"Herf SM","year":"1977","journal-title":"Am. 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