{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T14:07:55Z","timestamp":1791900475117,"version":"4.3.4"},"reference-count":28,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,6,15]],"date-time":"2016-06-15T00:00:00Z","timestamp":1465948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2016,10]]},"abstract":"Abstract<\/jats:title>Background and objective<\/jats:title>Limited data exist regarding factors predicting respiratory failure (RF) in non\u2010immunocompromised patients with adenovirus (AdV) pneumonia.<\/jats:p><\/jats:sec>Methods<\/jats:title>We described characteristics of AdV pneumonia (n<\/jats:italic>\u2009=\u200991) versus non\u2010AdV pneumonia (n<\/jats:italic>\u2009=\u200955) and compared clinico\u2010laboratory and radiological characteristics in patient groups categorized by RF.<\/jats:p><\/jats:sec>Results<\/jats:title>All 91 AdV pneumonia patients presented with acute respiratory symptoms and radiological infiltrations and had significantly lower levels of white blood cell counts and platelet counts compared with non\u2010AdV pneumonia. Of them, 67 patients had mild pneumonia without RF (non\u2010RF), 14 patients had no RF at admission but progressed to RF during hospitalization (progressed to RF) and 10 patients had RF at admission (initial RF). Initial monocyte percentage and absolute monocyte counts in RF patient groups (progressed to RF and initial RF) were significantly lower than those of non\u2010RF patients (both P<\/jats:italic>\u2009<\u20090.001), and the differences among progressed to RF and initial RF patients were not significant. Chest computed tomography findings such as dominant pattern or distribution, clinical symptoms, and bacterial or viral co\u2010infections other than AdV were not discriminable between patients who had RF and those who did not. On univariate analysis, initial monocytopenia, multilobar infiltrations and pleural effusion were associated with RF. However, on multivariable analysis, only initial monocytopenia remained significant (P<\/jats:italic>\u2009=\u20090.004) for predicting RF.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Our data suggest that initial monocytopenia may help to predict RF during the course of AdV pneumonia in non\u2010immunocompromised patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.12828","type":"journal-article","created":{"date-parts":[[2016,6,15]],"date-time":"2016-06-15T17:01:05Z","timestamp":1466010065000},"page":"1243-1250","source":"Crossref","is-referenced-by-count":29,"title":["Clinical characteristics and factors predicting respiratory failure in adenovirus pneumonia"],"prefix":"10.1111","volume":"21","author":[{"given":"Hee","family":"Yoon","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung Woo","family":"Jhun","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine The Armed Forces Capital Hospital Seongnam Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se Jin","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine The Armed Forces Capital Hospital Seongnam Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,6,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1283287"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199802270-00027"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2007.06.009"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2011.09.006"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-007-0312-6"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1967.03130120083029"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1086\/379127"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2003.44.4.732"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-007-0416-z"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-5-259"},{"key":"e_1_2_7_12_1","article-title":"Outcomes of early administration of cidofovir in non\u2010immunocompromised patients with severe adenovirus pneumonia","volume":"10","author":"Kim SJ","year":"2015","journal-title":"PLoS One"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2012.04.018"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-014-0456-6"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00563-08"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2005.131692"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.5669"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-199902000-00025"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2011.041152"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-14-147"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1089\/hum.1998.9.15-2207"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1998.tb01761.x"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.2217\/fvl.11.6"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.017905-0"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)81360-5"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.160.4.9804075"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1086\/511159"},{"key":"e_1_2_7_28_1","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1001\/archinte.1997.00440220040006","article-title":"The hospital admission decision for patients with community\u2010acquired pneumonia. 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