{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:18:24Z","timestamp":1792289904614,"version":"4.4.0"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,6,20]],"date-time":"2016-06-20T00:00:00Z","timestamp":1466380800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"AstraZeneca Latin America"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and objective<\/jats:title><jats:p>Opportunistic chronic obstructive pulmonary disease (COPD) case finding approaches for high\u2010risk individuals with or without symptoms is a feasible option for disease identification. PUMA is an opportunistic case finding study conducted in primary care setting of Argentina, Colombia, Venezuela and Uruguay. The objectives were to measure COPD prevalence in an at\u2010risk population visiting primary care for any reason, to assess the yield of this opportunistic approach and the accuracy of a score developed to detect COPD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Subjects attending routine primary care visits, \u226540\u2009years of age, current or former smokers or exposed to biomass smoke, completed a questionnaire and performed spirometry. COPD was defined as post\u2010bronchodilator (post\u2010BD) forced expiratory volume in 1\u2009s (FEV<jats:sub>1<\/jats:sub>)\/forced vital capacity (FVC)\u2009&lt;\u20090.70 and the lower limit of normal of FEV<jats:sub>1<\/jats:sub>\/FVC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1743 subjects completed the interview; 1540 performed acceptable spirometry. COPD prevalence was 20.1% (<jats:italic>n<\/jats:italic>\u2009=\u2009309; ranging from 11.0% in Venezuela to 29.6% in Argentina) when defined using post\u2010BD FEV<jats:sub>1<\/jats:sub>\/FVC\u2009&lt;\u20090.70, and 14.7% (<jats:italic>n<\/jats:italic>\u2009=\u2009226; ranging from 8.3% in Venezuela to 21.8% in Colombia) using the lower limit of normal. Logistic regression analysis for both definitions showed that the risk of COPD was significantly higher for persons &gt;50\u2009years, heavy smokers (&gt;30 pack\u2010years), with dyspnoea, and having prior spirometry. A simple score and a weighted score constructed using the following predictive factors: gender, age, pack\u2010years smoking, dyspnoea, sputum, cough and spirometry, had a mean accuracy for detecting COPD (post\u2010BD FEV<jats:sub>1<\/jats:sub>\/FVC\u2009&lt;\u20090.70) of 76% and 79% for the simple and weighted scores, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This simple seven\u2010item score is an accurate screening tool to select subjects for spirometry in primary care.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.12834","type":"journal-article","created":{"date-parts":[[2016,6,20]],"date-time":"2016-06-20T08:52:45Z","timestamp":1466412765000},"page":"1227-1234","source":"Crossref","is-referenced-by-count":54,"title":["Development of a simple screening tool for opportunistic COPD case finding in primary care in Latin America: The PUMA study"],"prefix":"10.1111","volume":"21","author":[{"given":"Maria Victorina","family":"L\u00f3pez Varela","sequence":"first","affiliation":[{"name":"Faculty of Medicine University of the Republic, Hospital Maciel  Montevideo Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Montes de Oca","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University Hospital of Caracas, Central University of Venezuela  Caracas Venezuela"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandra","family":"Rey","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of the Republic  Montevideo Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Casas","sequence":"additional","affiliation":[{"name":"Colombian Foundation of Pulmonology  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Stirbulov","sequence":"additional","affiliation":[{"name":"Faculty of Medical Science of Santa Casa de S\u00e3o Paulo  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Di Boscio","sequence":"additional","affiliation":[{"name":"Medical Affairs AstraZeneca Latin America  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the PUMA Team","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,6,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61728-0"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(13)70232-7"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S32330"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.13-0809"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67632-5"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61377-4"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00138409"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-1149"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S39555"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pupt.2009.09.005"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2007.085456"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201204-0596PP"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arbres.2014.11.017"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2010.06.020"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.3399\/bjgp13X660788"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.3132\/pcrj.2007.00009"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2006.06.027"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S16929"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.091784"},{"key":"e_1_2_8_21_1","first-page":"201","article-title":"Early detection of COPD in primary care: screening by invitation of smokers aged 40 to 55\u2009years","volume":"54","author":"Stratelis G","year":"2004","journal-title":"Br. 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