{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T20:41:22Z","timestamp":1767904882281,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,7,5]],"date-time":"2016-07-05T00:00:00Z","timestamp":1467676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2016,11]]},"abstract":"ABSTRACT<\/jats:title>Background and objective<\/jats:title>Obstructive sleep apnoea syndrome (OSAS<\/jats:styled-content>) is a common chronic systemic disease in the general population, with known associated cardiovascular outcomes. We aimed to investigate arterial stiffness in OSAS<\/jats:styled-content> patients and compare daytime and night\u2010time values with control subjects.<\/jats:p><\/jats:sec>Methods<\/jats:title>A total of 104 patients undergoing investigation for OSAS<\/jats:styled-content> with polysomnography also underwent pulse wave velocity (PWV<\/jats:styled-content>) and augmentation index (AIx<\/jats:styled-content>) measurements with Mobil\u2010O\u2010Graph for 24\u2009h. Eighty\u2010two patients were found to have OSAS<\/jats:styled-content> and 22 did not have OSAS<\/jats:styled-content> and acted as controls.<\/jats:p><\/jats:sec>Results<\/jats:title>\nPWV<\/jats:styled-content> values of the 82 OSAS<\/jats:styled-content> patients during the 24\u2010h period, both daytime and night\u2010time, were significantly higher than that of the control subjects. Moreover, night\u2010time levels of AIx<\/jats:styled-content> were significantly higher in OSAS<\/jats:styled-content> patients than control subjects (P<\/jats:italic>\u2009=\u20090.025). PWV<\/jats:styled-content> during night\u2010time was higher than daytime measurements in OSAS<\/jats:styled-content> patients (P<\/jats:italic>\u2009=\u20090.012). Apnoea hypopnoea index (AHI<\/jats:styled-content>) was significantly correlated with PWV<\/jats:styled-content> and AIx<\/jats:styled-content> over 24\u2009h (P<\/jats:italic>\u2009=\u20090.0001, r<\/jats:italic>\u2009=\u20090.412; P<\/jats:italic>\u2009=\u20090.002, r<\/jats:italic>\u2009=\u20090.333, respectively). Positive correlations were also found between oxygen desaturation index (ODI<\/jats:styled-content>) with PWV<\/jats:styled-content> and AIx<\/jats:styled-content> during the night (P<\/jats:italic>\u2009=\u20090.0001, r<\/jats:italic>\u2009=\u20090.480; P<\/jats:italic>\u2009=\u20090.002, r<\/jats:italic>\u2009=\u20090.325, respectively). However, daytime AIx<\/jats:styled-content> was not significantly correlated with ODI<\/jats:styled-content> (P<\/jats:italic>\u2009=\u20090.052, r<\/jats:italic>\u2009=\u20090.205).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>\nOSAS<\/jats:styled-content> patients, without known cardiovascular disease, have increased PWV<\/jats:styled-content>, indicating an increased arterial stiffness, compared with control subjects and correlations between AHI<\/jats:styled-content> and arterial stiffness indices suggest increased arterial stiffness with increased disease severity. Therefore, arterial stiffness should be considered as a possible cause for cardiovascular complications in OSAS<\/jats:styled-content> patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.12845","type":"journal-article","created":{"date-parts":[[2016,7,6]],"date-time":"2016-07-06T04:47:23Z","timestamp":1467780443000},"page":"1480-1485","source":"Crossref","is-referenced-by-count":8,"title":["Arterial stiffness in obstructive sleep apnoea: Is there a difference between daytime and night\u2010time?"],"prefix":"10.1111","volume":"21","author":[{"given":"Sevinc","family":"Sarinc Ulasli","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Department of Pulmonary Diseases Hacettepe University Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muzaffer","family":"Sariaydin","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pulmonary Diseases Afyon Kocatepe University Afyon Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gulay","family":"Ozkececi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Cardiology Afyon Kocatepe University Afyon Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ersin","family":"Gunay","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pulmonary Diseases Afyon Kocatepe University Afyon Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilal","family":"Halici","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pulmonary Diseases Afyon Kocatepe University Afyon Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Unlu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pulmonary Diseases Afyon Kocatepe University Afyon Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,7,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.2172"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.189420"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2014.80"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-015-1135-9"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2012.02212.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYP.0000000000000033"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2012.03.002"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.2147\/VHRM.S24877"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2012.78"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MBP.0b013e328338892f"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/MBP.0b013e328339be38"},{"key":"e_1_2_7_13_1","doi-asserted-by":"crossref","unstructured":"O'BrienE ParatiG StergiouG AsmarR BeilinL BiloG ClementD de laSierraA deLeeuwP DolanE et al.European Society of Hypertension Working Group on Blood Pressure Monitoring. 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