{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T05:28:41Z","timestamp":1771478921665,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,8,10]],"date-time":"2016-08-10T00:00:00Z","timestamp":1470787200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>\n<jats:styled-content style=\"fixed-case\">ABSTRACT<\/jats:styled-content>\n<\/jats:title><jats:sec><jats:title>Background and objective<\/jats:title><jats:p>Pneumonectomy (<jats:styled-content style=\"fixed-case\">PNE<\/jats:styled-content>) is a procedure infrequently performed in children. A high morbidity\/mortality rate associated with <jats:styled-content style=\"fixed-case\">PNE<\/jats:styled-content> has been described. Few series have been published in the last 15\u2009years. Risk factors associated with morbidity\/mortality after <jats:styled-content style=\"fixed-case\">PNE<\/jats:styled-content> were evaluated. Indications, course, survival and complications of <jats:styled-content style=\"fixed-case\">PNE<\/jats:styled-content> in children were also analized.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a case series of 51 children who underwent <jats:styled-content style=\"fixed-case\">PNE<\/jats:styled-content>, death within 30\u2009days of surgery, pneumonia, empyema, sepsis, adult respiratory distress syndrome, bronchopleural fistula, bleeding, pneumothorax and post\u2010<jats:styled-content style=\"fixed-case\">PNE<\/jats:styled-content> syndrome were considered major morbidities. Scoliosis, wound infection and atelectasis were considered minor morbidities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Median age at <jats:styled-content style=\"fixed-case\">PNE<\/jats:styled-content> was 7.4\u2009years; 45% were males. Indications of pneumonectomy were postinfectious bronchiectasis (61%), tumours (17%), pulmonary malformations (17%), aspiration syndrome (14%), cystic fibrosis (6%), immunodeficiency (4%) and trauma (2%). Mortality rate was 4% at 1\u2009month. Major and minor morbidities were present in 23% and 27% of patients, respectively. Risk factors for development of morbidities after <jats:styled-content style=\"fixed-case\">PNE<\/jats:styled-content> were age\u2009\u2264\u20093\u2009years (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>: 16.7; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 2.4\u2013117) and the need for mechanical ventilation for at least 4\u2009days (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>: 8; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 1.5\u201343.6).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Children are at high risk of death, major and minor morbidities following <jats:styled-content style=\"fixed-case\">PNE<\/jats:styled-content>. Caution is recommended for this group of patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.12867","type":"journal-article","created":{"date-parts":[[2016,8,11]],"date-time":"2016-08-11T03:26:44Z","timestamp":1470886004000},"page":"187-191","source":"Crossref","is-referenced-by-count":11,"title":["Risk factors for morbidities and mortality in children following pneumonectomy"],"prefix":"10.1111","volume":"22","author":[{"given":"Ver\u00f3nica","family":"Giubergia","sequence":"first","affiliation":[{"name":"Pulmonology Department Prof. Dr. Juan P. Garrahan Pediatric Hospital  Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florencia","family":"Alessandrini","sequence":"additional","affiliation":[{"name":"Pulmonology Department Prof. Dr. Juan P. 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Garrahan Pediatric Hospital  Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Casta\u00f1os","sequence":"additional","affiliation":[{"name":"Pulmonology Department Prof. Dr. Juan P. Garrahan Pediatric Hospital  Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,8,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(02)00404-9"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.10.007"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(03)00586-5"},{"key":"e_1_2_7_5_1","first-page":"115","article-title":"Childhood pneumonectomies: two decades\u2019 experience of a referral center","volume":"23","author":"Yalcin S","year":"2013","journal-title":"Eur. J. Pediatr. 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