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Although the\n                      <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content>\n                      has been developed for the assessment of\n                      <jats:styled-content style=\"fixed-case\">COPD<\/jats:styled-content>\n                      patients, it has not been fully evaluated exclusively in\n                      <jats:styled-content style=\"fixed-case\">IPF<\/jats:styled-content>\n                      . This study was designed to evaluate the validity of the\n                      <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content>\n                      in\n                      <jats:styled-content style=\"fixed-case\">IPF<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The clinical data for 106 consecutive subjects with newly diagnosed\n                      <jats:styled-content style=\"fixed-case\">IPF<\/jats:styled-content>\n                      who completed pulmonary function tests, partial pressure of oxygen in arterial blood (\n                      <jats:styled-content style=\"fixed-case\">\n                        PaO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:styled-content>\n                      ) at rest, 6\u2010min walk test (\n                      <jats:styled-content style=\"fixed-case\">6MWT<\/jats:styled-content>\n                      ),\n                      <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content>\n                      , St George's Respiratory Questionnaire (\n                      <jats:styled-content style=\"fixed-case\">SGRQ<\/jats:styled-content>\n                      ), modified Medical Research Council (\n                      <jats:styled-content style=\"fixed-case\">mMRC<\/jats:styled-content>\n                      ) dyspnoea grade and Hospital Anxiety and Depression Scale (\n                      <jats:styled-content style=\"fixed-case\">HADS<\/jats:styled-content>\n                      ), were analysed. We assessed the validity of the\n                      <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content>\n                      in comparison with the\n                      <jats:styled-content style=\"fixed-case\">SGRQ<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The present subjects showed mild to moderate restrictive impairment on spirometry. Mean\n                      <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content>\n                      score and total\n                      <jats:styled-content style=\"fixed-case\">SGRQ<\/jats:styled-content>\n                      were 12.8\u2009\u00b1\u20098.0 and 30.8\u2009\u00b1\u200917.7, respectively. The concurrent validity of the\n                      <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content>\n                      score in comparison with the\n                      <jats:styled-content style=\"fixed-case\">SGRQ<\/jats:styled-content>\n                      total score was significant (r\u2009=\u20090.72,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001). Internal consistency (Cronbach's \u03b1\u2009=\u20090.869) and repeatability over 3\u2009months (intraclass correlation coefficient\u2009=\u20090.742) of the\n                      <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content>\n                      were also significant. Single regression analysis showed that the\n                      <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content>\n                      had significant construct validity. In multiple regression analysis,\n                      <jats:styled-content style=\"fixed-case\">mMRC<\/jats:styled-content>\n                      ,\n                      <jats:styled-content style=\"fixed-case\">\n                        PaO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:styled-content>\n                      at rest, minimum\n                      <jats:styled-content style=\"fixed-case\">\n                        SpO\n                        <jats:sub>2<\/jats:sub>\n                      <\/jats:styled-content>\n                      during\n                      <jats:styled-content style=\"fixed-case\">6MWT<\/jats:styled-content>\n                      and anxiety of\n                      <jats:styled-content style=\"fixed-case\">HADS<\/jats:styled-content>\n                      were independent predictors for the\n                      <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The\n                      <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content>\n                      is a valid health status measurement in\n                      <jats:styled-content style=\"fixed-case\">IPF<\/jats:styled-content>\n                      patients. Multiple regression analysis showed that the\n                      <jats:styled-content style=\"fixed-case\">CAT<\/jats:styled-content>\n                      was significantly correlated with dyspnoea severity, oxygenation impairment and anxiety.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/resp.12936","type":"journal-article","created":{"date-parts":[[2016,11,9]],"date-time":"2016-11-09T18:20:51Z","timestamp":1478715651000},"page":"721-727","source":"Crossref","is-referenced-by-count":39,"title":["<scp>COPD A<\/scp>\n                    ssessment\n                    <scp>T<\/scp>\n                    est for measurement of health status in patients with idiopathic pulmonary fibrosis:\n                    <scp>A<\/scp>\n                    cross\u2010sectional study"],"prefix":"10.1111","volume":"22","author":[{"given":"Toshiaki","family":"Matsuda","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine and Allergy Tosei General Hospital  Nagoya Japan"},{"name":"Department of Respiratory Medicine Nagoya University Graduate School of Medicine  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Taniguchi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine and Allergy Tosei General Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiko","family":"Ando","sequence":"additional","affiliation":[{"name":"Center for Advanced Medicine and Clinical Research Nagoya University Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Kondoh","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine and Allergy Tosei General Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoki","family":"Kimura","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine and Allergy Tosei General Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kensuke","family":"Kataoka","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine and Allergy Tosei General Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Nagoya University Graduate School of Medicine  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine and Allergy Tosei General Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taiki","family":"Furukawa","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine and Allergy Tosei General Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinori","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Nagoya University Graduate School of Medicine  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,11,9]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"RaghuG CollardHR EganJJ MartinezFJ BehrJ BrownKK ColbyTV CordierJF FlahertyKR LaskyJAet al.;ATS\/ERS\/JRS\/ALAT Committee on Idiopathic Pulmonary Fibrosis. 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