{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T11:08:35Z","timestamp":1786619315280,"version":"build-2736575974"},"reference-count":28,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,3,4]],"date-time":"2018-03-04T00:00:00Z","timestamp":1520121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and objective<\/jats:title><jats:p>Bronchiectasis not associated with cystic fibrosis is an increasingly recognized chronic lung disease. In Oceania, indigenous populations experience a disproportionately high burden of disease. We aimed to describe the natural history of bronchiectasis and identify risk factors associated with premature mortality within a cohort of Aboriginal Australians, New Zealand M\u0101ori and Pacific Islanders, and non\u2010indigenous Australians and New Zealanders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective cohort study of bronchiectasis patients aged &gt;15 years at three hospitals: Alice Springs Hospital and Monash Medical Centre in Australia, and Middlemore Hospital in New Zealand. Data included demographics, ethnicity, sputum microbiology, radiology, spirometry, hospitalization and survival over 5 years of follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Aboriginal Australians were significantly younger and died at a significantly younger age than other groups. Age\u2010 and sex\u2010adjusted all\u2010cause mortality was higher for Aboriginal Australians (hazard ratio (HR): 3.9), and respiratory\u2010related mortality was higher for both Aboriginal Australians (HR: 4.3) and M\u0101ori and Pacific Islander people (HR: 1.7). Hospitalization was common: Aboriginal Australians had 2.9 admissions\/person\u2010year and 16.9 days in hospital\/person\u2010year. Despite Aboriginal Australians having poorer prognosis, calculation of the FACED score suggested milder disease in this group. Sputum microbiology varied with<jats:italic>Aspergillus fumigatus<\/jats:italic>more often isolated from non\u2010indigenous patients. Airflow obstruction was common (66.9%) but not invariable.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Bronchiectasis is not one disease. It has a significant impact on healthcare utilization and survival. Differences between populations are likely to relate to differing aetiologies and understanding the drivers of bronchiectasis in disadvantaged populations will be key.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.13280","type":"journal-article","created":{"date-parts":[[2018,3,4]],"date-time":"2018-03-04T11:12:44Z","timestamp":1520161964000},"page":"743-749","source":"Crossref","is-referenced-by-count":60,"title":["Bronchiectasis in indigenous and non\u2010indigenous residents of Australia and New Zealand"],"prefix":"10.1111","volume":"23","author":[{"given":"Sean R.","family":"Blackall","sequence":"first","affiliation":[{"name":"School of Medicine and Dentistry James Cook University Cairns QLD, Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae B.","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Middlemore Hospital, Counties Manukau District Health Board Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5197-1163","authenticated-orcid":false,"given":"Paul","family":"King","sequence":"additional","affiliation":[{"name":"Monash Respiratory and Sleep Medicine Monash Medical Centre Melbourne VIC, Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conroy","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Middlemore Hospital, Counties Manukau District Health Board Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lloyd","family":"Einsiedel","sequence":"additional","affiliation":[{"name":"Baker Heart and Diabetes Institute Melbourne VIC, Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7796-4447","authenticated-orcid":false,"given":"Marc G.W.","family":"R\u00e9mond","sequence":"additional","affiliation":[{"name":"Baker Heart and Diabetes Institute Melbourne VIC, Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cindy","family":"Woods","sequence":"additional","affiliation":[{"name":"School of Health University of New England Armidale NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graeme P.","family":"Maguire","sequence":"additional","affiliation":[{"name":"Baker Heart and Diabetes Institute Melbourne VIC, Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,3,4]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"842","article-title":"Bronchiectasis \u2013 a guide for primary care","volume":"41","author":"Maguire G","year":"2012","journal-title":"Aust. 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