{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T22:04:13Z","timestamp":1778623453675,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,9,12]],"date-time":"2018-09-12T00:00:00Z","timestamp":1536710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and objective<\/jats:title><jats:p>Inspiratory muscle training (IMT) enhances velocity of inspiratory muscle contraction and modifies inspiratory and expiratory time. This study aimed to examine the impact of high\u2010intensity IMT (H\u2010IMT) on exercise capacity in bronchiectasis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Forty\u2010five patients were included. Lung function, respiratory muscle strength and endurance, exercise capacity, dyspnoea, fatigue and quality of life (QOL) were evaluated. Patients were randomized into two groups: H\u2010IMT and control groups. Twenty\u2010three patients underwent H\u2010IMT for 8\u2009weeks, using threshold loading with a target workload of maximal inspiratory pressure (MIP) of at least 70%, with 3\u2010min\u2009cycles (as 2\u2010min training: 1\u2010min rest intervals) for 21\u2009min. There was a total period of 14\u2009min of loaded breathing and 7\u2009min of recovery. The control group (<jats:italic>n<\/jats:italic>\u2009=\u200922) underwent low\u2010intensity IMT at 10% of the initial MIP and was maintained at the same intensity until the end of the training.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After training, both MIP and maximal expiratory pressure (MEP) and the incremental shuttle walk distance were increased in the H\u2010IMT group compared with the control group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). There was a significant difference in constant threshold load, time and pressure\u2013time units in the H\u2010IMT group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) but not in the control group (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.05). A significant decrease was found in fatigue in both groups (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). The Leicester Cough Questionnaire social score for the H\u2010IMT group decreased significantly after the treatment (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The H\u2010IMT increased exercise capacity in patients with non\u2010cystic fibrosis bronchiectasis. It has also positive effects on respiratory muscle strength and endurance, and social aspects of QOL.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.13397","type":"journal-article","created":{"date-parts":[[2018,9,13]],"date-time":"2018-09-13T01:48:30Z","timestamp":1536803310000},"page":"246-253","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["High\u2010intensity inspiratory muscle training in bronchiectasis: A randomized controlled trial"],"prefix":"10.1111","volume":"24","author":[{"given":"Ozge","family":"Ozalp","sequence":"first","affiliation":[{"name":"Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation Hacettepe University Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8151-0664","authenticated-orcid":false,"given":"Deniz","family":"Inal\u2010Ince","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation Hacettepe University Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aslihan","family":"Cakmak","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation Hacettepe University Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ebru","family":"Calik\u2010Kutukcu","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation Hacettepe University Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melda","family":"Saglam","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation Hacettepe University Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sema","family":"Savci","sequence":"additional","affiliation":[{"name":"School of Physiotherapy and Rehabilitation Dokuz Eyl\u00fcl University Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naciye","family":"Vardar\u2010Yagli","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation Hacettepe University Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00fclya","family":"Arikan","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation Hacettepe University Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jale","family":"Karakaya","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Biostatistics Hacettepe University Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00fctfi","family":"Coplu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Chest Medicine Hacettepe University Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2004.028928"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.03.00301103"},{"key":"e_1_2_6_4_1","first-page":"57","article-title":"Respiratory muscle assessment","volume":"31","author":"Troosters T","year":"2005","journal-title":"Eur. 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