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While there are several bacteria and viruses associated with bronchiectasis, licensed vaccines are only currently available for <jats:italic>Streptococcus pneumoniae<\/jats:italic>, <jats:italic>Haemophilus influenzae<\/jats:italic> (<jats:italic>H. influenzae<\/jats:italic> protein D as a conjugate in a pneumococcal vaccine), <jats:italic>Mycobacterium tuberculosis, Bordetella pertussis<\/jats:italic> and influenza virus. The evidence for the efficacy and effectiveness of these vaccines in both preventing and managing bronchiectasis in children and adults is limited with the focus of most research being on other chronic lung disorders, such as chronic obstructive pulmonary diseases, asthma and cystic fibrosis. We review the existing evidence for these vaccines in bronchiectasis and highlight the existing gaps in knowledge. High\u2010quality experimental and non\u2010experimental studies using current state\u2010of\u2010the\u2010art microbiological methods and validated, standardised case definitions are needed across the depth and breadth of the vaccine development pathway.<\/jats:p>","DOI":"10.1111\/resp.13446","type":"journal-article","created":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T00:28:48Z","timestamp":1543278528000},"page":"107-114","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Paediatric and adult bronchiectasis: Vaccination in prevention and management"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8159-2620","authenticated-orcid":false,"given":"Kerry\u2010Ann F.","family":"O'Grady","sequence":"first","affiliation":[{"name":"Queensland University of Technology Institute of Health and Biomedical Innovation @ Centre for Children's Health Research  Brisbane QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan W.","family":"Cripps","sequence":"additional","affiliation":[{"name":"School of Medicine Griffith University  Gold Coast QLD Australia"},{"name":"Menzies Health Institute Queensland Griffith University  Gold Coast QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Grimwood","sequence":"additional","affiliation":[{"name":"School of Medicine Griffith University  Gold Coast QLD Australia"},{"name":"Menzies Health Institute Queensland Griffith University  Gold Coast QLD Australia"},{"name":"Department of Infectious Diseases Gold Coast Health  Gold Coast QLD Australia"},{"name":"Department of Paediatrics Gold Coast Health  Gold Coast QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,26]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"European Lung Whitebook: Respiratory Health and Disease in Europe","author":"European Respiratory Society","year":"2013"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201505-0926UP"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/rmed.2000.0823"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2010.10.009"},{"key":"e_1_2_7_6_1","first-page":"147","article-title":"Nontypeable Haemophilus influenzae and childhood pneumonia","volume":"53","author":"Cripps AW","year":"2010","journal-title":"P. 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