{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T11:20:48Z","timestamp":1785237648209,"version":"3.55.0"},"reference-count":40,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1040830"],"award-info":[{"award-number":["1040830"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1058213"],"award-info":[{"award-number":["1058213"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1161138"],"award-info":[{"award-number":["1161138"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1090440"],"award-info":[{"award-number":["1090440"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1075119"],"award-info":[{"award-number":["1075119"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and objective<\/jats:title><jats:p>Despite paediatric bronchiectasis being recognized increasingly worldwide, prior reports of hospitalization costs for bronchiectasis in children are lacking. This study aimed to (i) identify health service costs of hospitalizations and (ii) factors associated with these costs in children admitted to an Australian paediatric hospital following an acute exacerbation of their bronchiectasis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Demographic and hospital resource use data were prospectively recorded for 100 hospitalizations in 80 children aged &lt;18\u2009years admitted consecutively to the QCH, Brisbane, Australia. Costs (2016 AUD) were obtained from the hospital's Finance Department. Linear regressions, with bootstrap resampling to quantify uncertainty, were used to estimate factors affecting cost of hospitalization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 100 hospitalizations (48 males) had a median (IQR) age of 6.04 (4.04\u20139.85) years. Their mean (SD) LOS was 12.30 (4.60) days. The mean (SD) direct health service cost was AUD 30\u2009182 (13\u2009998) per hospitalization. The greatest contributor to costs was health professional wages, accounting for 70% of the cost per episode. LOS, younger age at admission and number of bronchiectatic lobes affected were associated with higher costs, whilst HITH service was associated with lower cost. The cost to families on average was AUD 2669.50 (SD: 991.50) per hospitalization when accounting for lost wages and opportunity cost.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The per episode healthcare cost burden of hospitalizations for paediatric bronchiectasis exacerbations is substantial. Interventions that prevent hospitalized exacerbations and reduce severity of childhood bronchiectasis with even moderate effectiveness are likely to result in substantial hospital costs savings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.13828","type":"journal-article","created":{"date-parts":[[2020,5,2]],"date-time":"2020-05-02T00:49:55Z","timestamp":1588380595000},"page":"1250-1256","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Cost of hospitalization for bronchiectasis exacerbation in children"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7533-2315","authenticated-orcid":false,"given":"Vikas","family":"Goyal","sequence":"first","affiliation":[{"name":"Department of Respiratory and Sleep Medicine Queensland Children's Hospital  Brisbane QLD Australia"},{"name":"Faculty of Medicine The University of Queensland  Brisbane QLD Australia"},{"name":"Centre for Children's Health Research Queensland University of Technology  Brisbane QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven M.","family":"McPhail","sequence":"additional","affiliation":[{"name":"Australian Centre for Health Services Innovation and School of Public Health and Social Work Queensland University of Technology  Brisbane QLD Australia"},{"name":"Clinical Informatics Metro South Health  Brisbane QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Hurley","sequence":"additional","affiliation":[{"name":"Department of Finance Queensland Children's Hospital  Brisbane QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Grimwood","sequence":"additional","affiliation":[{"name":"School of Medicine and Menzies Health Institute Queensland Griffith University  Gold Coast QLD Australia"},{"name":"Department of Infectious Diseases Gold Coast Health  Gold Coast QLD Australia"},{"name":"Department of Paediatrics Gold Coast Health  Gold Coast QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie M.","family":"Marchant","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Sleep Medicine Queensland Children's Hospital  Brisbane QLD Australia"},{"name":"Centre for Children's Health Research Queensland University of Technology  Brisbane QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I. Brent","family":"Masters","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Sleep Medicine Queensland Children's Hospital  Brisbane QLD Australia"},{"name":"Faculty of Medicine The University of Queensland  Brisbane QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1331-3706","authenticated-orcid":false,"given":"Anne B.","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Sleep Medicine Queensland Children's Hospital  Brisbane QLD Australia"},{"name":"Centre for Children's Health Research Queensland University of Technology  Brisbane QLD Australia"},{"name":"Child Health Division Menzies School of Health Research  Darwin NT Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23380"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2017.00027"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2018.02.024"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja14.00287"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201711-2202OC"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.13495"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0071109"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0162282"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-0099"},{"key":"e_1_2_8_11_1","first-page":"30","article-title":"Hospital admissions for non\u2010cystic fibrosis bronchiectasis in New Zealand","volume":"128","author":"Bibby S","year":"2015","journal-title":"N. Z. Med. J."},{"key":"e_1_2_8_12_1","unstructured":"Australian Institute of Health and Welfare. [Accessed 15 Aug 2019.] Available from URL:http:\/\/webarchive.nla.gov.au\/gov\/20170816061928\/http:\/\/www.aihw.gov.au\/bronchiectasis\/"},{"key":"e_1_2_8_13_1","unstructured":"O'GradyK RevellA MaguireG MillonigR NewmanM ReidD HillD ChangA. Lung health services for Aboriginal and Torres Strait Islander Peoples in Queensland. Queensland Health Brisbane Queensland Australia 2010."},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-2932"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-0679"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12890-019-0818-6"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/1479972316643698"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01888-2015"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/ip.6.3.177"},{"key":"e_1_2_8_20_1","unstructured":"Efficiency in Health. Commission research paper. Canberra: Productivity Commission 2015."},{"key":"e_1_2_8_21_1","unstructured":"Independent Hospital Pricing Authority (IHPA). Hospital patient costing standards version 3.1.2014. Available from URL:https:\/\/www.ihpa.gov.au\/sites\/g\/files\/net636\/f\/publications\/ahpcs-version3.1.pdf"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.24670"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.2165\/00019053-200826040-00001"},{"key":"e_1_2_8_24_1","unstructured":"Australian Bureau of Statistics. Average weekly earnings Australia May 2016 \u2018Table 3: average weekly earnings Australia original May 2016\u2019 Cat. no. 6302.0.2017. [Accessed 15 Aug 2019.] Available from URL:http:\/\/www.abs.gov.au\/ausstats\/abs@.nsf\/mf\/6302.0."},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02294361"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.2307\/2346405"},{"key":"e_1_2_8_27_1","unstructured":"PregibonD.Data Analytic Methods for Generalized Linear Models. University of Toronto (this is a PhD Thesis) 1979."},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-publhealth-040617-013517"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0006-341X.2000.00645.x"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1080\/21548331.2018.1505407"},{"key":"e_1_2_8_31_1","unstructured":"Review of the AR\u2010DRG classification case complexity process \u2013 final report.2014. Australian Consortium for classification development. Available from URL:www.accd.net.au"},{"key":"e_1_2_8_32_1","unstructured":"National Hospital Cost Data Collection. Public hospitals cost report round 20 (financial year 2015\u201016). 2018. Available from URL:https:\/\/www.ihpa.gov.au\/publications\/national-hospital-cost-data-collection-public-hospitals-cost-report-round-20-0."},{"key":"e_1_2_8_33_1","unstructured":"Australian Consortium for Classification Development. AR\u2010DRG version 9.0 e final report.2016. [Accessed Aug 2019.] Available from URL:https:\/\/www.ihpa.gov.au\/sites\/g\/files\/net636\/f\/publications\/ar-drg_v9.0_final_report.pdf"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1159\/000489935"},{"key":"e_1_2_8_35_1","first-page":"20","article-title":"Healthcare cost and utilization before and after diagnosis of Pseudomonas aeruginosa among patients with non\u2010cystic fibrosis bronchiectasis in the U.S","volume":"5","author":"Blanchette CM","year":"2017","journal-title":"Med. Sci. (Basel)"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00026313"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201309-1575OC"},{"key":"e_1_2_8_38_1","unstructured":"Australian Institute of Health and Welfare. Hospital performance: costs of acute admitted patients in public hospitals from 2012\u201313 to 2014\u201315. Canberra: AIHW 2018."},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21518"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(19)30254-1"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-019-4414-5"}],"container-title":["Respirology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fresp.13828","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/resp.13828","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/resp.13828","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/resp.13828","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T21:20:59Z","timestamp":1693862459000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/resp.13828"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":40,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10.1111\/resp.13828"],"URL":"https:\/\/doi.org\/10.1111\/resp.13828","archive":["Portico"],"relation":{},"ISSN":["1323-7799","1440-1843"],"issn-type":[{"value":"1323-7799","type":"print"},{"value":"1440-1843","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"2019-09-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}