{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T16:47:47Z","timestamp":1791478067621,"version":"4.3.4"},"reference-count":41,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,11,8]],"date-time":"2020-11-08T00:00:00Z","timestamp":1604793600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and objective<\/jats:title><jats:p>IPF is a chronic progressive lung disease in which PR provides benefit for patients. PD, a TCM PR programme, has known effectiveness in COPD, but its utility in IPF is unknown. We investigated its effectiveness and safety in patients with IPF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A 6\u2010month randomized controlled trial (RCT) was conducted in three Chinese clinics. Ninety\u2010six participants diagnosed with IPF were randomly assigned to one of the three groups: the PD group received a PD programme two times a day, 5\u2009days\/week for 2\u2009months, and the exercise group exercised via a stationary cycle ergometer, 30\u2009min\/day, 5\u2009days\/week for 2\u2009months. Volunteers in the control group were advised to maintain their usual activities. Primary outcomes were changes from baseline in the 6MWD and HRQoL score on the SGRQ\u2010I at 1 and 2\u2009months (at the end of the intervention) and at 6\u2009months (4\u2009months after the intervention). Secondary outcomes measures included FVC, DL<jats:sub>CO<\/jats:sub> (% predicted) and the changes in mMRC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The 6MWD was increased in the PD group compared to exercise and control groups. 6MWD increased by 60.44\u2009m in the PD group, 32.16\u2009m in the exercise group and 12.42\u2009m in controls after the 2\u2009months of rehabilitation programme. The between\u2010group differences in the change from baseline were 28.78\u2009m (95% CI: 0.54 to 56.01; <jats:italic>P<\/jats:italic> = 0.044) and 48.02\u2009m (95% CI: 23.04 to 73.00; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) at 2\u2009months, and 25.61\u2009m (95% CI: \u22120.67 to 51.89; <jats:italic>P<\/jats:italic> = 0.058) and 50.93\u2009m (95% CI: 25.47 to 76.40; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) at 6\u2009months, respectively, including a difference exceeding the MCID. There was no significant change in the SGRQ\u2010I score, the mMRC dyspnoea score, FVC and DL<jats:sub>CO<\/jats:sub> (% predicted) in either the PD or exercise groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Two months after the intervention, a clinically meaningful difference in 6MWD was observed favouring the PD programme. The PD programme is safe and effective as a rehabilitation intervention designed to increase exercise tolerance and is an appropriate substitute for PR.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.13972","type":"journal-article","created":{"date-parts":[[2020,11,9]],"date-time":"2020-11-09T02:39:13Z","timestamp":1604889553000},"page":"360-369","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Pulmonary Daoyin as a traditional Chinese medicine rehabilitation programme for patients with <scp>IPF<\/scp>: A randomized controlled trial"],"prefix":"10.1111","volume":"26","author":[{"given":"Miao","family":"Zhou","sequence":"first","affiliation":[{"name":"Co\u2010Construction Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases by Henan and Education Ministry of P.R. China Henan University of Chinese Medicine  Zhengzhou China"},{"name":"Department of Respiratory The Third Affiliated Hospital of Henan University of Chinese Medicine  Zhengzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3808-6586","authenticated-orcid":false,"given":"Hailong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Co\u2010Construction Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases by Henan and Education Ministry of P.R. 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