{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:25:48Z","timestamp":1787502348162,"version":"build-2736575974"},"reference-count":49,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T00:00:00Z","timestamp":1652745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1028368"],"award-info":[{"award-number":["1028368"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1127060"],"award-info":[{"award-number":["1127060"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["334047"],"award-info":[{"award-number":["334047"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01AG029824"],"award-info":[{"award-number":["U01AG029824"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U19AG062682"],"award-info":[{"award-number":["U19AG062682"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008018","name":"Victorian Cancer Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008018","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001779","name":"Monash University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001779","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and objective<\/jats:title>\n                    <jats:p>The clinical significance of sleep\u2010disordered breathing (SDB) in older age is uncertain. This study determined the prevalence and associations of SDB with mood, daytime sleepiness, quality of life (QOL) and cognition in a relatively healthy older Australian cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional analysis was conducted from the Study of Neurocognitive Outcomes, Radiological and retinal Effects of Aspirin in Sleep Apnoea. Participants completed an unattended limited channel sleep study to measure the oxygen desaturation index (ODI) to define mild (ODI 5\u201315) and moderate\/severe (ODI\u2009\u2265\u200915) SDB, the Centre for Epidemiological Studies Scale, the Epworth Sleepiness Scale, the 12\u2010item Short\u2010Form for QOL and neuropsychological tests.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 1399 participants (mean age 74.0\u2009years), 36% (273 of 753) of men and 25% (164 of 646) of women had moderate\/severe SDB. SDB was associated with lower physical health\u2010related QOL (mild SDB: beta coefficient [\n                      <jats:italic>\u03b2<\/jats:italic>\n                      ] \u22122.5, 95% CI \u22123.6 to \u22121.3,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u20090.001; moderate\/severe SDB:\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u22121.8, 95% CI \u22123.0 to \u22120.6,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.005) and with lower global composite cognition (mild SDB:\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u22120.1, 95% CI \u22120.2 to 0.0,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.022; moderate\/severe SDB:\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u22120.1, 95% CI \u22120.2 to 0.0,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.032) compared to no SDB. SDB was not associated with daytime sleepiness nor depression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>SDB was associated with lower physical health\u2010related quality of life and cognitive function. Given the high prevalence of SDB in older age, assessing QOL and cognition may better delineate subgroups requiring further management, and provide useful treatment target measures for this age group.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/resp.14279","type":"journal-article","created":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T13:01:47Z","timestamp":1652792507000},"page":"767-775","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Sleep\u2010disordered breathing was associated with lower health\u2010related quality of life and cognitive function in a cross\u2010sectional study of older adults"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1439-3373","authenticated-orcid":false,"given":"Stephanie A.","family":"Ward","sequence":"first","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria"},{"name":"Centre for Healthy Brain Ageing (CHeBA), School of Psychiatry University of New South Wales  Kensington New South Wales"},{"name":"Department of Geriatric Medicine Prince of Wales Hospital  Randwick New South Wales"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsdon","family":"Storey","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danijela","family":"Gasevic","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria"},{"name":"Centre for Global Health Research, Usher Institute The University of Edinburgh  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2734-0841","authenticated-orcid":false,"given":"Matthew T.","family":"Naughton","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Alfred Hospital  Melbourne Victoria Australia"},{"name":"The Central Clinical School Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1744-2839","authenticated-orcid":false,"given":"Garun S.","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Department of Lung, Sleep, Allergy and Immunology Monash Health  Clayton Victoria Australia"},{"name":"School of Clinical Sciences Monash University  Clayton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth E.","family":"Trevaks","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2126-1045","authenticated-orcid":false,"given":"Rory","family":"Wolfe","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5099-3184","authenticated-orcid":false,"given":"Fergal J.","family":"O'Donoghue","sequence":"additional","affiliation":[{"name":"Institute for Breathing and Sleep Austin Health  Heidelberg Victoria Australia"},{"name":"Faculty of Medicine, Dentistry and Health Sciences University of Melbourne  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel","family":"Stocks","sequence":"additional","affiliation":[{"name":"Discipline of General Practice Adelaide Medical School, University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter P.","family":"Abhayaratna","sequence":"additional","affiliation":[{"name":"College of Health and Medicine Australian National University  Acton Australian Capital Territory Australia"},{"name":"Academic Unit of Internal Medicine Canberra Hospital  Garran Australian Capital Territory Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharyn","family":"Fitzgerald","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne G.","family":"Orchard","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne","family":"Ryan","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"McNeil","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher M.","family":"Reid","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria"},{"name":"Curtin School of Population Health Curtin University  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robyn L.","family":"Woods","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,17]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"142","article-title":"A comprehensive review of obstructive sleep apnea","volume":"14","author":"Abbasi A","year":"2021","journal-title":"Sleep Sci"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2015-206970"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043104"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.202006-696FR"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2020.06.002"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-015-1171-5"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1183\/20734735.003216"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/33.4.515"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.13321"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(15)00043-0"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00177411"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2869.2009.00754.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1241224"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.25117"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1721694115"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.2644"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.4986"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2017.06.010"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2017.2180"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2019.101250"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci11060706"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-141860"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2017.10.016"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2013.09.014"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1800722"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.26861"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.1115"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/14.6.540"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1177\/014662167700100306"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2020.1214"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-018-2040-z"},{"key":"e_1_2_10_33_1","first-page":"314","article-title":"The Modified Mini\u2010Mental State (3MS) examination","volume":"48","author":"Teng EL","year":"1987","journal-title":"J Clin Psychiatry"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1076\/clin.13.3.348.1749"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/arclin\/11.4.329"},{"key":"e_1_2_10_36_1","volume-title":"Symbol digit modalities test (SDMT). Manual (revised)","author":"Smith A","year":"1982"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glw342"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.9378"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.12770"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2007.11.009"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(14)70172-9"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.13728"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11065-017-9344-6"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0078655"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsy184"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.5434"},{"key":"e_1_2_10_47_1","first-page":"179","article-title":"Sleep breathing disorders and cognitive function in the elderly: an 8\u2010year follow\u2010up study. The Proof\u2010Synapse Cohort","volume":"38","author":"Martin MS","year":"2014","journal-title":"Sleep"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(12)70291-0"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000913"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-11-78"}],"container-title":["Respirology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/resp.14279","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/resp.14279","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/resp.14279","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T04:56:11Z","timestamp":1692766571000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/resp.14279"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,17]]},"references-count":49,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1111\/resp.14279"],"URL":"https:\/\/doi.org\/10.1111\/resp.14279","archive":["Portico"],"relation":{},"ISSN":["1323-7799","1440-1843"],"issn-type":[{"value":"1323-7799","type":"print"},{"value":"1440-1843","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,17]]},"assertion":[{"value":"2021-12-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}