{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T17:48:40Z","timestamp":1793296120440,"version":"4.5.0"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,3,2]],"date-time":"2023-03-02T00:00:00Z","timestamp":1677715200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1170958"],"award-info":[{"award-number":["1170958"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1154302"],"award-info":[{"award-number":["1154302"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This position statement, updated from the 2015 guidelines for managing Australian and New Zealand children\/adolescents and adults with chronic suppurative lung disease (CSLD) and bronchiectasis, resulted from systematic literature searches by a multi\u2010disciplinary team that included consumers. The main statements are:\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>Diagnose CSLD and bronchiectasis early; this requires awareness of bronchiectasis symptoms and its co\u2010existence with other respiratory diseases (e.g., asthma, chronic obstructive pulmonary disease).<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Confirm bronchiectasis with a chest computed\u2010tomography scan, using age\u2010appropriate protocols and criteria in children.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Undertake a baseline panel of investigations.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Assess baseline severity, and health impact, and develop individualized management plans that include a multi\u2010disciplinary approach and coordinated care between healthcare providers.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Employ intensive treatment to improve symptom control, reduce exacerbation frequency, preserve lung function, optimize quality\u2010of\u2010life and enhance survival. In children, treatment also aims to optimize lung growth and, when possible, reverse bronchiectasis.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Individualize airway clearance techniques (ACTs) taught by respiratory physiotherapists, encourage regular exercise, optimize nutrition, avoid air pollutants and administer vaccines following national schedules.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Treat exacerbations with 14\u2010day antibiotic courses based upon lower airway culture results, local antibiotic susceptibility patterns, clinical severity and patient tolerance. Patients with severe exacerbations and\/or not responding to outpatient therapy are hospitalized for further treatments, including intravenous antibiotics and intensive ACTs.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>\n                          Eradicate\n                          <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                          when newly detected in lower airway cultures.\n                        <\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Individualize therapy for long\u2010term antibiotics, inhaled corticosteroids, bronchodilators and mucoactive agents.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Ensure ongoing care with 6\u2010monthly monitoring for complications and co\u2010morbidities.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>Undertake optimal care of under\u2010served peoples, and despite its challenges, delivering best\u2010practice treatment remains the overriding aim.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:p>","DOI":"10.1111\/resp.14479","type":"journal-article","created":{"date-parts":[[2023,3,2]],"date-time":"2023-03-02T19:49:15Z","timestamp":1677786555000},"page":"339-349","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":80,"title":["Thoracic Society of Australia and New Zealand (\n                    <scp>TSANZ<\/scp>\n                    ) position statement on\n                    <scp>chronic suppurative lung disease and bronchiectasis in children<\/scp>\n                    ,\n                    <scp>adolescents and adults in Australia and New Zealand<\/scp>"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1331-3706","authenticated-orcid":false,"given":"Anne B.","family":"Chang","sequence":"first","affiliation":[{"name":"Australian Centre for Health Services Innovation Queensland University of Technology  Brisbane Queensland Australia"},{"name":"Department of Respiratory &amp; Sleep Medicine Queensland Children's Hospital  Brisbane Queensland Australia"},{"name":"NHMRC Centre for Research Excellence in Paediatric Bronchiectasis (AusBREATHE), Child Health Division, Menzies School of Health Research Charles Darwin University  Darwin Northern Territory Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8651-7139","authenticated-orcid":false,"given":"Scott C.","family":"Bell","sequence":"additional","affiliation":[{"name":"Thoracic Medicine The Prince Charles Hospital  Brisbane Queensland Australia"},{"name":"Faculty of Medicine University of Queensland  Brisbane Queensland Australia"},{"name":"Translational Research Institute  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine A.","family":"Byrnes","sequence":"additional","affiliation":[{"name":"Department of Paediatrics University of Auckland  Auckland New Zealand"},{"name":"Starship Children's Hospital  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Dawkins","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Middlemore Hospital  Auckland New Zealand"},{"name":"University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2061-845X","authenticated-orcid":false,"given":"Anne E.","family":"Holland","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy Alfred Health  Melbourne Victoria Australia"},{"name":"Central Clinical School Monash University  Melbourne Victoria Australia"},{"name":"Institute for Breathing and Sleep  Heidelberg Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Kennedy","sequence":"additional","affiliation":[{"name":"College of Medicine and Public Health Flinders University  Darwin Northern Territory Australia"},{"name":"Board of Northern Territory General Practice Education Ltd  Darwin Northern Territory Australia"},{"name":"Pandanus Medical NT  Millner Northern Territory Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5197-1163","authenticated-orcid":false,"given":"Paul T.","family":"King","sequence":"additional","affiliation":[{"name":"Departments of Respiratory and Sleep Medicine and Medicine, Monash Medical Centre Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9799-0471","authenticated-orcid":false,"given":"Pamela","family":"Laird","sequence":"additional","affiliation":[{"name":"Department Physiotherapy Perth Children's Hospital  Perth Western Australia Australia"},{"name":"Wal\u2010yan Respiratory Research Centre Telethon Kids Institute  Perth Western Australia Australia"},{"name":"Department of Paediatrics, School of Medicine University of WA  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Mooney","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Middlemore Hospital  Auckland New Zealand"},{"name":"School of Clinical Sciences AUT University  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucy","family":"Morgan","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine at Concord and Nepean Hospitals School of Medicine, Faculty of Medicine and Health, University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Parsons","sequence":"additional","affiliation":[{"name":"Representative of Parent Advisory Group, NHMRC Centre of Research Excellence in Paediatric Bronchiectasis, Cough and Airways Research Group, Australian Centre for Health Services Innovation Queensland University of Technology  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betty","family":"Poot","sequence":"additional","affiliation":[{"name":"Respiratory Department Hutt Hospital, Te Whatu Ora Capital, Coast and Hutt Valley  Lower Hutt New Zealand"},{"name":"School of Nursing Midwifery, and Health Practice Victoria University of Wellington  Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maree","family":"Toombs","sequence":"additional","affiliation":[{"name":"School of Public Health University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Torzillo","sequence":"additional","affiliation":[{"name":"Nganampa Health Council  Alice Springs Northwest Territories Australia"},{"name":"Royal Prince Alfred Hospital University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Grimwood","sequence":"additional","affiliation":[{"name":"School of Medicine and Dentistry, Menzies Health Institute Queensland Griffith University  Southport Queensland Australia"},{"name":"Departments of Infectious Diseases and Paediatrics Gold Coast Health  Southport Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,2]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)31554-X"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2018-212463"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-018-0042-3"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja14.00287"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.13495"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02392-2018"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01033-2015"},{"key":"e_1_2_10_9_1","unstructured":"Telfar\u2010BarnardL ZhangJ.The impact of respiratory disease in New Zealand: 2018 update. University of Otago. 2018 [cited 2022 Jan 12]. Available from:https:\/\/www.asthmafoundation.org.nz\/research\/the\u2010impact\u2010of\u2010respiratory\u2010disease\u2010in\u2010new\u2010zealand\u20102018\u2010update; 2018"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.13828"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/1479972317702139"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23380"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.24491"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.15264"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.13280"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.13291"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02990-2020"},{"key":"e_1_2_10_18_1","unstructured":"ChangAB BellSC TorzilloPJ KingPT ByrnesCA MaguireGP et al.Thoracic Society of Australia and New Zealand. Chronic suppurative lung disease and bronchiectasis in children and adults in Australian and New Zealand. Available from:http:\/\/www.thoracic.org.au\/journal\u2010publishing\/command\/download_file\/id\/36\/filename\/TSANZ\u2010ChronicSuppurativeLungDisease\u2010Guidelines\u20102016\u2010web.pdf.2014"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2010.tb03949.x"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2008.tb02085.x"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2002.tb04733.x"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2019.10.020"},{"key":"e_1_2_10_23_1","article-title":"Dual antibiotics for bronchiectasis","volume":"6","author":"Felix LM","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_24_1","first-page":"176","volume-title":"The European lung white book","author":"European Respiratory Society","year":"2014"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(19)30185-7"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(19)30191-2"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01269-2018"}],"container-title":["Respirology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/resp.14479","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/resp.14479","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/resp.14479","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T10:25:23Z","timestamp":1692440723000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/resp.14479"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,2]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1111\/resp.14479"],"URL":"https:\/\/doi.org\/10.1111\/resp.14479","archive":["Portico"],"relation":{},"ISSN":["1323-7799","1440-1843"],"issn-type":[{"value":"1323-7799","type":"print"},{"value":"1440-1843","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,2]]},"assertion":[{"value":"2022-10-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}