{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:40:07Z","timestamp":1759333207121,"version":"3.40.5"},"reference-count":34,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T00:00:00Z","timestamp":1686528000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003669","name":"Korea Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["2016\u2010ER6703\u201000","2019\u2010ER6701\u201000"],"award-info":[{"award-number":["2016\u2010ER6703\u201000","2019\u2010ER6701\u201000"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objective<\/jats:title><jats:p>Preterm birth or fetal growth has been associated with reduced lung function and asthma during childhood in the general population. We aimed to elucidate whether prematurity or fetal growth has a significant influence on lung function or symptoms in children with stable asthma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included children with stable asthma who participated in the Korean childhood Asthma Study cohort. Asthma symptoms were determined by asthma control test (ACT). Percent predicted values of pre\u2010 and post\u2010bronchodilator (BD) lung function including forced expiratory volume in 1\u2009second (FEV<jats:sub>1<\/jats:sub>), forced vital capacity (FVC), and forced expiratory flow at 25%\u201375% of FVC (FEF<jats:sub>25%\u201375%<\/jats:sub>) were measured. Lung function and symptoms were compared according to the history of preterm birth and birth weight (BW) for gestational age (GA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study population consisted of 566 children (age range: 5\u201318\u2009years). There were no significant differences in lung function and ACT between preterm and term subjects. We observed no significant difference in ACT but significant differences were observed in pre\u2010 and post\u2010BD FEV<jats:sub>1<\/jats:sub>, pre\u2010 and post\u2010BD FVC, and post\u2010BD FEF<jats:sub>25%\u201375%<\/jats:sub> according to BW for GA in total subjects. Two\u2010way ANOVA revealed that BW for GA rather than prematurity was a significant determining factor for pre\u2010 and post\u2010BD lung function. After regression analysis, BW for GA was still a significant determining factor of pre\u2010 and post\u2010BD FEV<jats:sub>1<\/jats:sub> and pre\u2010 and post\u2010BD FEF<jats:sub>25%\u201375%<\/jats:sub>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Fetal growth rather than prematurity appears to have a significant effect on lung function in children with stable asthma.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.14528","type":"journal-article","created":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T23:49:50Z","timestamp":1686613790000},"page":"841-850","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Fetal growth rather than prematurity determines lung function in children with asthma"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5952-7849","authenticated-orcid":false,"given":"Hwan Soo","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Bucheon St. Mary's Hospital, College of Medicine The Catholic University of Korea  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung Won","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Precision Medicine Sungkyunkwan University School of Medicine  Suwon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Tack","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, College of Medicine The Catholic University of Korea, Uijeongbu St. Mary's Hospital  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung Hoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Asan Institute for Life Sciences, University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dae Hyun","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, College of Medicine Inha University  Incheon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Woo Kyung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Inje University Seoul Paik Hospital  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dae Jin","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Korea University Guro Hospital  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Korea University Anam Hospital  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7817-8728","authenticated-orcid":false,"given":"Dong In","family":"Suh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Seoul National University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hey Sung","family":"Baek","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Hallym University Kangdong Sacred Heart Hospital  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meeyong","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Soonchunhyang University School of Medicine  Bucheon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Won","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Seoul National University College of Medicine  Seongnam Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gwang Cheon","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics National Health Insurance Service Ilsan Hospital  Ilsan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyeon\u2010Jong","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Pediatric Allergy and Respiratory Center Soonchunhyang University College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Chonnam National University Hospital, Chonnam National University Medical School  Gwangju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ju Hee","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Dankook University Hospital  Cheonan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Il","family":"Woo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, College of Medicine Chungbuk National University  Cheongju Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyung Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Pusan National University Yangsan Hospital  Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youn Ho","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Gangnam CHA Medical Center CHA University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5600-3441","authenticated-orcid":false,"given":"Ju Suk","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Samsung Changwon Hospital Sungkyunkwan University School of Medicine  Changwon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sungsu","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Pusan National University Yangsan Hospital  Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nang Kyeong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Precision Medicine Sungkyunkwan University School of Medicine  Suwon Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinho","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Childhood Asthma Atopy Center, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,6,12]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"National Asthma Education and Prevention Program.Third Expert Panel on the Diagnosis and Management of Asthma. Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma. National Heart Lung and Blood Institute (US) Bethesda MD; 2007."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00397-2015"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2016.10.010"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200912-1806OC"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1309220"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.24050"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e896"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.06.043"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001596"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2015.08.050"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.12.1082"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12890-019-0829-3"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.4168\/aair.2021.13.1.42"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.161.1.ats11-99"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1465-9921-6-144"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00034805"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00080312"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12402"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2003.09.008"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.12.662"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60364-4"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.3345\/kjp.2018.61.5.135"},{"volume-title":"Linear mixed models: a practical guide using statistical software","year":"2015","author":"West BT","key":"e_1_2_10_24_1"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2017-314541"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1586172"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(21)00508-7"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202001-0194OC"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.24222"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201703-0631OC"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201509-578OC"},{"key":"e_1_2_10_32_1","first-page":"1147","article-title":"Fetal growth and childhood lung function in the Swedish Twin Study on prediction and prevention of asthma","volume":"14","author":"\u00d6rtqvist AK","year":"2017","journal-title":"Ann Am Thorac Soc"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.14379"},{"key":"e_1_2_10_34_1","first-page":"1186","article-title":"Long\u2010term effects of bronchopulmonary dysplasia on lung function: a pilot study in preschool children's cohort","volume":"1","author":"Manti S","year":"2020","journal-title":"J Asthma"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2020.05.553"}],"container-title":["Respirology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/resp.14528","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T23:56:24Z","timestamp":1692662184000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/resp.14528"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,12]]},"references-count":34,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1111\/resp.14528"],"URL":"https:\/\/doi.org\/10.1111\/resp.14528","archive":["Portico"],"relation":{},"ISSN":["1323-7799","1440-1843"],"issn-type":[{"type":"print","value":"1323-7799"},{"type":"electronic","value":"1440-1843"}],"subject":[],"published":{"date-parts":[[2023,6,12]]},"assertion":[{"value":"2022-12-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}