{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T22:04:00Z","timestamp":1777413840074,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,12,3]],"date-time":"2023-12-03T00:00:00Z","timestamp":1701561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP597411"],"award-info":[{"award-number":["APP597411"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Objective<\/jats:title><jats:p>Dyspnoea is a debilitating symptom in individuals with chronic obstructive pulmonary disease (COPD) and a range of other chronic cardiopulmonary diseases and is often associated with anxiety and depression. The present study examined the effect of visually\u2010induced mood shifts on exertional dyspnoea in individuals with COPD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Following familiarization, 20 participants with mild to severe COPD (age 57\u201379\u2009years) attended three experimental sessions on separate days, performing two 5\u2010min treadmill exercise tests separated by a 30\u2010min interval on each day. During each exercise test, participants viewed either a positive, negative or neutral set of images sourced from the International Affective Picture System (IAPS) and rated dyspnoea or leg fatigue (0\u201310). Heart rate (HR) and peripheral oxygen saturation (SpO<jats:sub>2<\/jats:sub>) were measured at 1\u2010min intervals during each test. Mood valence ratings were obtained using Self\u2010Assessment Manikin (SAM) scale (1\u20139).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mood valence ratings were significantly higher when viewing positive (end\u2010exercise mean\u2009\u00b1\u2009SEM\u2009=\u20097.6\u2009\u00b1\u20090.3) compared to negative IAPS images (2.4\u2009\u00b1\u20090.3, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Dyspnoea intensity (mean\u2009\u00b1\u2009SEM\u2009=\u20095.8\u2009\u00b1\u20090.4) and dyspnoea unpleasantness (5.6\u2009\u00b1\u20090.3) when viewing negative images were significantly higher compared to positive images (4.2\u2009\u00b1\u20090.4, <jats:italic>p<\/jats:italic>\u2009=\u20090.004 and 3.4\u2009\u00b1\u20090.5, <jats:italic>p<\/jats:italic>\u2009=\u20090.003). Eighty\u2010five percent of participants (<jats:italic>n<\/jats:italic>\u2009=\u200917) met the minimal clinically important difference (MCID) criteria for both dyspnoea intensity and unpleasantness. HR, SpO<jats:sub>2<\/jats:sub> and leg fatigue did not differ significantly between conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These findings indicate that the negative <jats:italic>affective<\/jats:italic> state worsens dyspnoea in COPD, thereby suggesting strategies aimed at reducing the likelihood of negative mood or improving the mood may be effective in managing morbidity associated with dyspnoea in COPD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/resp.14642","type":"journal-article","created":{"date-parts":[[2023,12,4]],"date-time":"2023-12-04T06:24:52Z","timestamp":1701671092000},"page":"201-208","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Effect of experimental modulation of mood on exertional dyspnoea in chronic obstructive pulmonary disease"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5602-4496","authenticated-orcid":false,"given":"Pramod","family":"Sharma","sequence":"first","affiliation":[{"name":"School of Health Sciences and Social Work Menzies Health Institute Queensland, Griffith University  Gold Coast Queensland Australia"},{"name":"The Prince Charles Hospital, Allied Health Research Collaborative Metro North Hospital and Health Service  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karlijn","family":"Scheffer","sequence":"additional","affiliation":[{"name":"School of Health Sciences and Social Work Menzies Health Institute Queensland, Griffith University  Gold Coast Queensland Australia"},{"name":"Department of Physiology Radboud University Medical Center, Radboud Institute for Health Sciences  Nijmegen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Menaka","family":"Louis","sequence":"additional","affiliation":[{"name":"School of Health Sciences and Social Work Menzies Health Institute Queensland, Griffith University  Gold Coast Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9675-3549","authenticated-orcid":false,"given":"Craig R.","family":"Aitken","sequence":"additional","affiliation":[{"name":"School of Health Sciences and Social Work Menzies Health Institute Queensland, Griffith University  Gold Coast Queensland Australia"},{"name":"The Prince Charles Hospital, Allied Health Research Collaborative Metro North Hospital and Health Service  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lewis","family":"Adams","sequence":"additional","affiliation":[{"name":"School of Health Sciences and Social Work Menzies Health Institute Queensland, Griffith University  Gold Coast Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4054-4662","authenticated-orcid":false,"given":"Norman R.","family":"Morris","sequence":"additional","affiliation":[{"name":"School of Health Sciences and Social Work Menzies Health Institute Queensland, Griffith University  Gold Coast Queensland Australia"},{"name":"The Prince Charles Hospital, Allied Health Research Collaborative Metro North Hospital and Health Service  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,12,3]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201111-2042ST"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-017-3677-9"},{"key":"e_1_2_11_4_1","first-page":"PA3306","article-title":"Impact of exacerbation of COPD on anxiety and depression symptoms and dyspnea in the activities of daily living","volume":"46","author":"Gianjoppe\u2010Santos J","year":"2015","journal-title":"Eur Respir J"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.2011.01344.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2018-212683"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00122.2015"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.2006.00415.x"},{"key":"e_1_2_11_9_1","unstructured":"LangPJ.International affective picture system (IAPS): affective ratings of pictures and instruction manual. 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