{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T20:10:02Z","timestamp":1790971802031,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T00:00:00Z","timestamp":1719964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Fifty years since its inception, Light's criteria have aided in classifying pleural effusions (PEs) as exudates if 1 or more criteria are met. Thoracic ultrasound (US) emerges as a non\u2010invasive technique for point of care use especially if pleural procedures are contemplated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We aimed to develop a score based on radiological and US features that could separate exudates from transudates without serum and pleural fluid biochemical tests necessary for Light's criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective review of consecutive patients with PE who underwent thoracocentesis was performed. CXRs were evaluated for laterality followed by US for echogenicity, pleural nodularity, thickening and septations. PE was classified as exudate or transudate according to Light's criteria and corroborated with albumin gradient. A score combining radiological and US features was developed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We recruited 201 patients with PE requiring thoracocentesis. Mean age was 64\u2009years, 51% were females, 164 (81.6%) were exudates, and 37 (18.4%) were transudates. Assigning 1\u2010point for\n                      <jats:italic>D<\/jats:italic>\n                      iaphragmatic nodularity,\n                      <jats:italic>U<\/jats:italic>\n                      nilateral,\n                      <jats:italic>E<\/jats:italic>\n                      chogenicity, Pleural\n                      <jats:italic>T<\/jats:italic>\n                      hickening and\n                      <jats:italic>S<\/jats:italic>\n                      eptations, DUETS ranged from 1 to 5. DUETS \u22652 indicated high likelihood for exudate (PPV 98.8%, NPV 100%) with 1% misclassification versus 6.9% using Light's criteria (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>DUETS separated exudates from transudates with good accuracy, and could obviate paired serum and pleural fluid tests necessary for Light's criteria computation. Our study reflected real world practice where DUETS performed better than Light's criteria for PE that arose from more than one disease processes, and in the evaluation of patients with PE who have received diuretics.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/resp.14780","type":"journal-article","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T20:15:22Z","timestamp":1720037722000},"page":"976-984","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["<scp>DUETS<\/scp>\n                    for Light's in separating exudate from transudate"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7733-1014","authenticated-orcid":false,"given":"Astrid","family":"Gardiner","sequence":"first","affiliation":[{"name":"Division of Respiratory and Critical Care Medicine National University Hospital  Singapore Singapore"},{"name":"Department of Sleep and Respiratory Medicine Royal Prince Alfred Hospital  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"Ling","sequence":"additional","affiliation":[{"name":"Yong Loo Lin School of Medicine National University Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiong\u2010Huak","family":"Chan","sequence":"additional","affiliation":[{"name":"Biostatistics Unit, Yong Loo Lin School of Medicine National University Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2734-8061","authenticated-orcid":false,"given":"Jose","family":"Porcel","sequence":"additional","affiliation":[{"name":"Pleural Medicine Unit, Department of Internal Medicine Arnau de Vilanova University Hospital, University of Lleida  Lleida Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0036-511X","authenticated-orcid":false,"given":"Y. C. Gary","family":"Lee","sequence":"additional","affiliation":[{"name":"Pleural Medicine Unit Institute of Respiratory Health  Perth Australia"},{"name":"Department of Respiratory Medicine Sir Charles Gairdner Hospital  Perth Australia"},{"name":"Centre for Respiratory Health, School of Medicine &amp; Pharmacology University of Western Australia  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia\u2010Meng","family":"Teoh","sequence":"additional","affiliation":[{"name":"Division of Respiratory and Critical Care Medicine National University Hospital  Singapore Singapore"},{"name":"Yong Loo Lin School of Medicine National University Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei\u2010Fong","family":"Liew","sequence":"additional","affiliation":[{"name":"Division of Respiratory and Critical Care Medicine National University Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeevesh","family":"Kapur","sequence":"additional","affiliation":[{"name":"Diagnostic Imaging National University Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seow\u2010Ping","family":"Low","sequence":"additional","affiliation":[{"name":"Division of Respiratory and Critical Care Medicine National University Hospital  Singapore Singapore"},{"name":"Yong Loo Lin School of Medicine National University Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1846-8341","authenticated-orcid":false,"given":"Pyng","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Respiratory and Critical Care Medicine National University Hospital  Singapore Singapore"},{"name":"Yong Loo Lin School of Medicine National University Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1201\/b19146"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-77-4-507"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.159.1.1609716"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2010.137026"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2008.100545"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198912000-00008"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.122.5.1524"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.08.1286"},{"key":"e_1_2_10_10_1","first-page":"116","article-title":"Efficacy of CT in diagnosis of transudates and exudates in patients with pleural effusion","volume":"20","author":"\u00c7ullu N","year":"2014","journal-title":"Diagn Interv Radiol"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2012.02155.x"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.99.5.1097"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.108.5.1260"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.98.1.141"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2000.095"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.110.1.97"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.5.3291"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2010.136978"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13089-011-0066-3"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.06.00113205"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2020.02.051"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201601-082OC"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/jhm.981"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjms.2016.08.016"},{"key":"e_1_2_10_25_1","unstructured":"National Patient Safety Agency.Risks of chest drain insertion. 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