{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T03:42:38Z","timestamp":1791517358109,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T00:00:00Z","timestamp":1759363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T00:00:00Z","timestamp":1759363200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objective<\/jats:title>\n                    <jats:p>Lobectomy is the primary treatment for early\u2010stage non\u2010small cell lung cancer. However, pulmonary function declines postoperatively, presenting a significant challenge. This study investigated pulmonary function following lobectomy and compared these changes with predicted lung function based on the traditional segmental method, focusing on resected lobe\u2010specific variability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This prospective cohort study included 419 patients who underwent lobectomies for NSCLC. Pulmonary function tests measuring forced vital capacity (FVC), forced expiratory volume in one second (FEV\n                      <jats:sub>1<\/jats:sub>\n                      ), and diffusion capacity for carbon monoxide (DLCO) were conducted preoperatively and at 1, 3, 6, and 12\u2009months postoperatively. We compared the observed pulmonary function values to the predicted postoperative (PPO) values based on the traditional segmental method and analysed lobe\u2010specific differences using mixed\u2010effects models.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Left upper and right lower lobectomies demonstrated observed pulmonary function values similar to their PPOs as early as 2\u2009weeks postoperatively. However, the other lobes declined significantly, with an approximately 25% reduction in FVC, FEV1, and DLCO, regardless of the number of segments in the lobe. Three months postoperatively, observed pulmonary function values exceeded PPO values across all lobes. Surgical approach (open vs. video\u2010assisted thoracoscopic surgery), right upper lobectomy in the reference to right lower lobectomy, and postoperative decreased physical activity were significant factors related to the non\u2010recovery of lung function to their PPOs at 6\u2009months after surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Postoperative pulmonary function recovery varied significantly by resected lobe, with most lobes showing better recovery than predicted postoperative values. Accurate outcome prediction requires accounting for lobe\u2010specific characteristics and compensatory mechanisms.\n                      <jats:boxed-text content-type=\"graphic\" position=\"anchor\">\n                        <jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/resp70133-gra-0001-m.png\">\n                          <jats:alt-text>image<\/jats:alt-text>\n                        <\/jats:graphic>\n                      <\/jats:boxed-text>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/resp.70133","type":"journal-article","created":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T13:03:50Z","timestamp":1759410230000},"page":"62-72","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Lobe\u2010Specific Variability in Postoperative Pulmonary Function in Lung Cancer Patients: A Longitudinal Analysis and Comparison With Traditional Predictive Models"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6745-6131","authenticated-orcid":false,"given":"Yeong Jeong","family":"Jeon","sequence":"first","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Samsung Medical Center, Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumin","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, College of Medicine Ewha Womans University, Mokdong Hospital  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunga","family":"Kong","sequence":"additional","affiliation":[{"name":"Patient\u2010Centered Outcomes Research Institute Samsung Medical Center  Seoul South Korea"},{"name":"Department of Clinical Research Design and Evaluation, SAIHST Sungkyunkwan University  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seongwoo","family":"Yang","sequence":"additional","affiliation":[{"name":"Center for Clinical Epidemiology, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong Ho","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Samsung Medical Center, Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong Kwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Samsung Medical Center, Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Mog","family":"Shim","sequence":"additional","affiliation":[{"name":"Department 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