{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:25:30Z","timestamp":1763036730971},"reference-count":86,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2013,1,11]],"date-time":"2013-01-11T00:00:00Z","timestamp":1357862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Risk Analysis"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:p><jats:italic>Listeria monocytogenes<\/jats:italic> is a leading cause of hospitalization, fetal loss, and death due to foodborne illnesses in the United States. A quantitative assessment of the relative risk of listeriosis associated with the consumption of 23 selected categories of ready\u2010to\u2010eat foods, published by the U.S. Department of Health and Human Services and the U.S. Department of Agriculture in 2003, has been instrumental in identifying the food products and practices that pose the greatest listeriosis risk and has guided the evaluation of potential intervention strategies. Dose\u2010response models, which quantify the relationship between an exposure dose and the probability of adverse health outcomes, were essential components of the risk assessment. However, because of data gaps and limitations in the available data and modeling approaches, considerable uncertainty existed. Since publication of the risk assessment, new data have become available for modeling <jats:italic>L. monocytogenes<\/jats:italic> dose\u2010response. At the same time, recent advances in the understanding of <jats:italic>L. monocytogenes<\/jats:italic> pathophysiology and strain diversity have warranted a critical reevaluation of the published dose\u2010response models. To discuss strategies for modeling <jats:italic>L. monocytogenes<\/jats:italic> dose\u2010response, the Interagency Risk Assessment Consortium (IRAC) and the Joint Institute for Food Safety and Applied Nutrition (JIFSAN) held a scientific workshop in 2011 (details available at <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/foodrisk.org\/irac\/events\/\">http:\/\/foodrisk.org\/irac\/events\/<\/jats:ext-link>). The main findings of the workshop and the most current and relevant data identified during the workshop are summarized and presented in the context of <jats:italic>L. monocytogenes<\/jats:italic> dose\u2010response. This article also discusses new insights on dose\u2010response modeling for <jats:italic>L. monocytogenes<\/jats:italic> and research opportunities to meet future needs.<\/jats:p>","DOI":"10.1111\/risa.12005","type":"journal-article","created":{"date-parts":[[2013,1,12]],"date-time":"2013-01-12T00:14:26Z","timestamp":1357949666000},"page":"1568-1581","source":"Crossref","is-referenced-by-count":21,"title":["New Data, Strategies, and Insights for <i>Listeria monocytogenes<\/i> Dose\u2010Response Models: Summary of an Interagency Workshop, 2011"],"prefix":"10.1111","volume":"33","author":[{"given":"K.","family":"Hoelzer","sequence":"first","affiliation":[{"name":"Center for Food Safety and Applied Nutrition Food and Drug Administration  College Park MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Chen","sequence":"additional","affiliation":[{"name":"Center for Food Safety and Applied Nutrition Food and Drug Administration  College Park MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Dennis","sequence":"additional","affiliation":[{"name":"Center for Food Safety and Applied Nutrition Food and Drug Administration  College Park MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Evans","sequence":"additional","affiliation":[{"name":"Center for Food Safety and Applied Nutrition Food and Drug Administration  College Park MD USA"},{"name":"Microbiology Issues Branch, Office of Public Health Science Food Safety and Inspection Service United States Department of Agriculture  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Pouillot","sequence":"additional","affiliation":[{"name":"Center for Food Safety and Applied Nutrition Food and Drug Administration  College Park MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. 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