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To assess the relative contribution of DTLNs to human salmonellosis occurrence associated with ground pork consumption and to investigate potential critical control points in the slaughter\u2010to\u2010table continuum for the control of human salmonellosis in the United States, a quantitative microbial risk assessment (QMRA) model was established. The model predicted an average of 45 cases of salmonellosis (95% CI = [19, 71]) per 100,000 Americans annually due to WFGP consumption. Sensitivity analysis of all stochastic input variables showed that cooking temperature was the most influential parameter for reducing salmonellosis cases associated with WFGP meals, followed by storage temperature and <jats:italic>Salmonella<\/jats:italic> concentration on contaminated carcass surface before fabrication. The input variables were grouped to represent three main factors along the slaughter\u2010to\u2010table chain influencing <jats:italic>Salmonella<\/jats:italic> doses ingested via WFGP meals: DTLN\u2010related factors, factors at processing other than DTLNs, and consumer\u2010related factors. The evaluation of the impact of each group of factors by second\u2010order Monte Carlo simulation showed that DTLN\u2010related factors had the lowest impact on the risk estimate among the three groups of factors. These findings indicate that interventions to reduce <jats:italic>Salmonella<\/jats:italic> contamination in DTLNs or to remove DTLNs from WFGP products may be less critical for reducing human infections attributable to ground pork than improving consumers\u2019 cooking habits or interventions of carcass decontamination at processing.<\/jats:p>","DOI":"10.1111\/risa.13317","type":"journal-article","created":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T03:26:46Z","timestamp":1556681206000},"page":"2237-2258","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Interventions Targeting Deep Tissue Lymph Nodes May Not Effectively Reduce the Risk of Salmonellosis from Ground Pork Consumption: A Quantitative Microbial Risk Assessment"],"prefix":"10.1111","volume":"39","author":[{"given":"Yangjunna","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Food Science and Technology University of Nebraska\u2013Lincoln  Lincoln NE USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annette M.","family":"O'Connor","sequence":"additional","affiliation":[{"name":"Department of Veterinary Diagnostic and Production Animal Medicine Iowa State University  Ames IA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Veterinary Diagnostic and Production Animal Medicine Iowa State University  Ames IA USA"},{"name":"Department of Statistics Iowa State University  Ames IA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James S.","family":"Dickson","sequence":"additional","affiliation":[{"name":"Department of Animal Science Iowa State University  Ames IA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. 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