{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T05:37:58Z","timestamp":1773466678838,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T00:00:00Z","timestamp":1565568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003193","name":"Ministerstvo \u0161kolstva, vedy, v\u00fdskumu a \u0161portu Slovenskej republiky","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003193","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010783","name":"Slovensk\u00e1 Akad\u00e9mia Vied","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010783","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006109","name":"Vedeck\u00e1 Grantov\u00e1 Agent\u00fara M\u0160VVa\u0160 SR a SAV","doi-asserted-by":"publisher","award":["1\/0213\/18"],"award-info":[{"award-number":["1\/0213\/18"]}],"id":[{"id":"10.13039\/501100006109","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Risk Analysis"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>After smoking, exposure to radon and its progeny is the second leading cause of lung cancer. The probability of inducing lung carcinomas by inhaled radon progeny depends on the deposited radiation dose, and is significantly affected by physiological and morphometric changes induced by smoking. Due to irritation of the airways, the inhalation of cigarette smoke leads to the hyperproduction of mucus. Two concurrent processes occur: on one hand, increased production of mucus protects the target cells against radiation damage; on the other hand, in the case of long\u2010term smokers, a chronic lung obstruction develops, causing an increase in the radiation dose to the lungs. Depending on the duration and intensity of smoking, these processes contribute to the final radiation dose with different weights. The primary objective of this study was to investigate to what extent these smoke\u2010induced changes can modify the resulting absorbed dose of inhaled radon progeny relative to healthy nonsmokers. Since the bronchial dose depends on the degree of lung tissue damage, we have used this dose as a tool for detecting the effects of smoking on the lung epithelium. In other words, the biological effect of radon served as a tracer of changes induced by smoking.<\/jats:p>","DOI":"10.1111\/risa.13385","type":"journal-article","created":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T17:59:10Z","timestamp":1565632750000},"page":"370-384","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Radon as a Tracer of Lung Changes Induced by Smoking"],"prefix":"10.1111","volume":"40","author":[{"given":"Radoslav","family":"B\u00f6hm","sequence":"first","affiliation":[{"name":"Faculty of Mathematics and Physics, Comenius University  Bratislava Slovak Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anton\u00edn","family":"Sedl\u00e1k","sequence":"additional","affiliation":[{"name":"National Radiation Protection Institute  Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2786-6843","authenticated-orcid":false,"given":"Martin","family":"Bulko","sequence":"additional","affiliation":[{"name":"Faculty of Mathematics and Physics, Comenius University  Bratislava Slovak Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karol","family":"Hol\u00fd","sequence":"additional","affiliation":[{"name":"Faculty of Mathematics and Physics, Comenius University  Bratislava Slovak Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,8,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/rpd\/ncp183"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.rpd.a006173"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/rpd\/ncu059"},{"key":"e_1_2_7_5_1","doi-asserted-by":"crossref","unstructured":"B\u00f6hm R. Sedl\u00e1k A. Bulko M. &Hol\u00fd K.(2019).Lung regeneration in abstaining smokers.Radiation Protection Dosimetry(in press).","DOI":"10.1093\/rpd\/ncz239"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004032-200004000-00003"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/rpd\/31.1-4.405"},{"key":"e_1_2_7_8_1","doi-asserted-by":"crossref","unstructured":"International Commission on Radiological Protection [ICRP]. (1994).Human respiratory tract model for radiological protection. ICRP Publication 66 Ann. ICRP 24(1\u20133).","DOI":"10.1016\/0146-6453(94)90018-3"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgm234"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.rpd.a006200"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004032-199107000-00013"},{"key":"e_1_2_7_12_1","volume-title":"Health effects of exposure to radon: BEIR VI","author":"National Research Council [NRC]","year":"1999"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/09553000110035233"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1667\/0033-7587(2002)157[0092:DOSEIS]2.0.CO;2"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004032-199605000-00009"},{"key":"e_1_2_7_16_1","unstructured":"Tom\u00e1\u0161ek L.(2016).Lung cancer risk from radon and smoking: Additive or multiplicative effect?8th Conference on Protection Against Radon at Home and at Work Prague Czech Republic September 12\u201316 2016 (p. 48). Czech Technical University in Prague."},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2005.11.087"}],"container-title":["Risk Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/risa.13385","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/risa.13385","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/risa.13385","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T18:23:59Z","timestamp":1694111039000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/risa.13385"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,12]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1111\/risa.13385"],"URL":"https:\/\/doi.org\/10.1111\/risa.13385","archive":["Portico"],"relation":{},"ISSN":["0272-4332","1539-6924"],"issn-type":[{"value":"0272-4332","type":"print"},{"value":"1539-6924","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,12]]},"assertion":[{"value":"2018-10-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}