{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T06:36:01Z","timestamp":1791441361463,"version":"4.3.3"},"reference-count":92,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T00:00:00Z","timestamp":1679875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52078314"],"award-info":[{"award-number":["52078314"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Risk Analysis"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Exploring transmission risk of different routes has major implications for epidemic control. However, disciplinary boundaries have impeded the dissemination of epidemic information, have caused public panic about \u201cair transmission,\u201d \u201cair\u2010conditioning transmission,\u201d and \u201cenvironment\u2010to\u2010human transmission,\u201d and have triggered \u201chygiene theater.\u201d Animal experiments provide experimental evidence for virus transmission, but more attention is paid to whether transmission is driven by droplets or aerosols and using the dichotomy to describe most transmission events. Here, according to characteristics of experiment setups, combined with patterns of human social interactions, we reviewed and grouped animal transmission experiments into four categories\u2014close contact, short\u2010range, fomite, and aerosol exposure experiments\u2014and provided enlightenment, with experimental evidence, on the transmission risk of severe acute respiratory syndrome coronavirus (SARS\u2010COV\u20102) in humans via different routes. When referring to \u201cair transmission,\u201d context should be showed in elaboration results, rather than whether close contact, short or long range is uniformly described as \u201cair transmission.\u201d Close contact and short range are the major routes. When face\u2010to\u2010face, unprotected, horizontally directional airflow does promote transmission, due to virus decay and dilution in air, the probability of \u201cair conditioning transmission\u201d is low; the risk of \u201cenvironment\u2010to\u2010human transmission\u201d highly relies on surface contamination and human behavior based on indirect path of \u201cfomite\u2010hand\u2010mucosa or conjunctiva\u201d and virus decay on surfaces. Thus, when discussing the transmission risk of SARS\u2010CoV\u20102, we should comprehensively consider the biological basis of virus transmission, environmental conditions, and virus decay. Otherwise, risk of certain transmission routes, such as long\u2010range and fomite transmission, will be overrated, causing public excessive panic, triggering ineffective actions, and wasting epidemic prevention resources.<\/jats:p>","DOI":"10.1111\/risa.14129","type":"journal-article","created":{"date-parts":[[2023,3,28]],"date-time":"2023-03-28T05:06:28Z","timestamp":1679979988000},"page":"2840-2857","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Review of animal transmission experiments of respiratory viruses: Implications for transmission risk of SARS\u2010COV\u20102 in humans via different routes"],"prefix":"10.1111","volume":"44","author":[{"given":"Ying","family":"Li","sequence":"first","affiliation":[{"name":"MOE Key Laboratory of Deep Earth Science and Engineering College of Architecture and Environment, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Mao","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Deep Earth Science and Engineering Institute for Disaster Management and Reconstruction, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Guo","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Deep Earth Science and Engineering Institute for Disaster Management and Reconstruction, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luyao","family":"Guo","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Deep Earth Science and Engineering College of Architecture and Environment, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linlin","family":"Chen","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Deep Earth Science and Engineering Institute for Disaster Management and Reconstruction, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zhao","sequence":"additional","affiliation":[{"name":"China Academy of Building Research  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingqin","family":"Wang","sequence":"additional","affiliation":[{"name":"China Academy of Building Research  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0774-4275","authenticated-orcid":false,"given":"Enshen","family":"Long","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Deep Earth Science and Engineering College of Architecture and Environment, Sichuan University  Chengdu China"},{"name":"MOE Key Laboratory of Deep Earth Science and Engineering Institute for Disaster Management and Reconstruction, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics11030427"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010020\u201017888\u2010w"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2015.06.002"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(07)70029\u20104"},{"key":"e_1_2_7_6_1","unstructured":"Britannica. 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