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Now is the time to start preparing our buildings, public opinion, and regulatory environments for the infectious aerosol management interventions necessary to protect the public. But which interventions should governments and institutions invest in the most? We review the leading candidate methods for infectious aerosol management and discuss their respective advantages, disadvantages, and suitable settings. There is strong emerging evidence that two recently explored technologies, direct exposure to far\u2010ultraviolet\u2010C (UVC) light and triethylene glycol, are particularly efficacious and safe, but there remain open questions about the long\u2010term safety and efficacy of these interventions. In the meantime, we recommend other interventions\u2014especially upper\u2010room UVC and in\u2010room air cleaners\u2014for settings where most occupants regularly spend more than a small fraction of their day. We conclude by listing research questions about these interventions that still need to be researched in social science, product development, medicine, engineering, economics, and ethics.<\/jats:p>","DOI":"10.1111\/risa.70054","type":"journal-article","created":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T19:59:05Z","timestamp":1751918345000},"page":"3045-3078","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Managing infectious aerosols to counter engineered pandemics: Current recommendations and future research"],"prefix":"10.1111","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6699-7785","authenticated-orcid":false,"given":"Adam","family":"Lerner","sequence":"first","affiliation":[{"name":"Institute for Health, Health Care Policy and Aging Research, School of Public Health Rutgers University  New Brunswick New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5837-0413","authenticated-orcid":false,"given":"Gediminas","family":"Mainelis","sequence":"additional","affiliation":[{"name":"Department of Environmental Sciences, School of Environmental and Biological Sciences Rutgers University  New Brunswick New Jersey USA"},{"name":"Environmental and Occupational Health Sciences Institute, School of Public Health Rutgers University  Piscataway New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4524-9876","authenticated-orcid":false,"given":"William","family":"Hallman","sequence":"additional","affiliation":[{"name":"Department of Human Ecology School of Environmental and Biological Sciences, Rutgers University  New Brunswick New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6608-3126","authenticated-orcid":false,"given":"Howard","family":"Kipen","sequence":"additional","affiliation":[{"name":"Environmental and Occupational Health Sciences Institute, School of Public Health Rutgers University  Piscataway New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5527-8622","authenticated-orcid":false,"given":"Monica","family":"Magalhaes","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Jos\u00e9 Luiz Egydio Set\u00fabal  S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7336-4321","authenticated-orcid":false,"given":"Brian","family":"Buckley","sequence":"additional","affiliation":[{"name":"Environmental and Occupational Health Sciences Institute, School of Public Health Rutgers University  Piscataway New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7098-0954","authenticated-orcid":false,"given":"Jos\u00e9 Guillermo","family":"Cede\u00f1o Laurent","sequence":"additional","affiliation":[{"name":"Environmental and Occupational Health Sciences Institute, School of Public Health Rutgers University  Piscataway New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1056-6609","authenticated-orcid":false,"given":"Nir","family":"Eyal","sequence":"additional","affiliation":[{"name":"Institute for Health, Health Care Policy and Aging Research, School of Public Health Rutgers University  New Brunswick New Jersey USA"},{"name":"Department of Philosophy School of Arts and Sciences Rutgers University  New Brunswick New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,7]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Abboushi B. 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