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Other systemic complications may lead to oral abnormalities similar to those seen in triple X patients, such as congenital hypothyroidism (CH). This paper reports a triple X syndrome case associated with CH later treated. Besides delay in cognitive and intellectual development, the patient had changes in teeth development and in cephalometric measurements with deficiencies in the maxilla and mandible. This is the first report of a triple X syndrome associated with CH. Both conditions may result in changes in dentofacial development.<\/jats:p>","DOI":"10.1111\/scd.12050","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T02:24:19Z","timestamp":1381544659000},"page":"156-159","source":"Crossref","is-referenced-by-count":3,"title":["Craniofacial and dental manifestations of triple X syndrome associated with congenital hypothyroidism: a case report"],"prefix":"10.1111","volume":"34","author":[{"given":"K\u00edvia Linhares","family":"Ferrazzo","sequence":"first","affiliation":[{"name":"Professor of Oral Medicine, School of Dentistry Franciscan University Center  Santa Maria\/Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcia Rodrigues","family":"Payeras","sequence":"additional","affiliation":[{"name":"Professor of Oral Pathology, School of Dentistry Franciscan University Center  Santa Maria\/Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vilmar Antonio","family":"Ferrazzo","sequence":"additional","affiliation":[{"name":"Professor of Orthodontics School of Dentistry, Federal University of Santa Maria  Santa Maria\/Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maur\u00edcio Barbieri","family":"Mezomo","sequence":"additional","affiliation":[{"name":"Professor of Orthodontics, School of Dentistry Franciscan University Center  Santa Maria\/Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(59)90415-5"},{"key":"e_1_2_5_3_1","first-page":"754","article-title":"The parental origin of the extra X chromosome in 47,XXX females","volume":"46","author":"May KM","year":"1990","journal-title":"Am J Hum Genet"},{"key":"e_1_2_5_4_1","first-page":"326","article-title":"Divergent phenotypes among 48,XXXX and 47,XXX females","volume":"22","author":"Telfer MA","year":"1970","journal-title":"Am J Hum Genet"},{"key":"e_1_2_5_5_1","first-page":"5","article-title":"A review of trisomy X (47,XXX)","volume":"11","author":"Tartaglia NR","year":"2010","journal-title":"Orphanet J Rare Dis"},{"key":"e_1_2_5_6_1","first-page":"214","article-title":"Triple\u2010X syndrome accompanied by single maxillary central incisor: case report","volume":"15","author":"Miura M","year":"1993","journal-title":"Pediatr Dent"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cji016"},{"key":"e_1_2_5_8_1","first-page":"167","article-title":"Dental changes in juvenile hypothyrodism","volume":"33","author":"Hinrichs EH","year":"1966","journal-title":"J Dent Child."},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1987.0254"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2002.0299"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-008-0040-7"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(83)80228-5"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2010.0005"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-5-17"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.67.1.87"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2005.05.070"},{"key":"e_1_2_5_17_1","first-page":"1","article-title":"CDC growth charts for the United States: methods and development. 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