{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,7]],"date-time":"2024-09-07T00:38:23Z","timestamp":1725669503674},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,12,10]],"date-time":"2013-12-10T00:00:00Z","timestamp":1386633600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The dental management of a patient presenting with both Down syndrome and neurofibromatosis type 1 (NF1) has not previously been described well in the dental literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Description<\/jats:title><jats:p>A 20\u2010year\u2010old male with both of these genetic anomalies sought comprehensive treatment at the Special Needs Dental clinic at the Arizona School of Dentistry and Oral Health. He presented with multiple decayed surfaces, retained primary teeth, and intra\/extra oral soft tissue tumors. Dental extractions and tumor reduction surgery took place at a private dental office due to the need for intravenous sedation for patient management. At the conclusion of the patient's \u00adtreatment, while his oral health was improved, there was little improvement in the facial aesthetics of his case.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Implications<\/jats:title><jats:p>Coordinating care among health care providers in a patient with Trisomy 21 and NF1 is essential for a reliable and predictable outcome. However, as neurofibromas are often known to recur, the treatment risks and advantages should be reviewed prior to surgical intervention.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.12062","type":"journal-article","created":{"date-parts":[[2013,12,10]],"date-time":"2013-12-10T08:32:40Z","timestamp":1386664360000},"page":"313-318","source":"Crossref","is-referenced-by-count":4,"title":["Down syndrome and neurofibromatosis: a case report"],"prefix":"10.1111","volume":"34","author":[{"given":"Rebecca","family":"Schaffer","sequence":"first","affiliation":[{"name":"Assistant Professor, Special Care Dentistry Associate Administrative Director AEGD AT Still University, Arizona School of Dentistry and Oral Health Mesa Arizona"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsay","family":"Goss","sequence":"additional","affiliation":[{"name":"Associate Dean for Post\u2010Doctoral Education, Director, Special Care Dentistry AT Still University, Arizona School of Dentistry &amp; Oral Health Mesa Arizona"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maureen Munnelly","family":"Romer","sequence":"additional","affiliation":[{"name":"Associate Dean for Post\u2010Doctoral Education, Director, Special Care Dentistry AT Still University, Arizona School of Dentistry &amp; Oral Health Mesa Arizona"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabah","family":"Kalamchi","sequence":"additional","affiliation":[{"name":"Professor, Assistant Dean for Surgery, Director Oral and Maxillary Facial Surgery, AT Still University, Arizona School of Dentistry &amp; Oral Health Mesa Arizona"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,12,10]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/oso\/9780195118612.003.0003","volume-title":"Syndromes of the head and neck,","author":"Gorlin RJ","year":"2001"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20735"},{"key":"e_1_2_5_4_1","unstructured":"MR\/DD Data Brief:Prevalence of mental retardation and\/or developmental disabilities: analysis of the 1994\/1995 NHIS\u2010D.April 2000 Vol. 2 No.1. Available at:http:\/\/rtc.umn.edu\/docs\/dddb2\u20101.pdf. Accessed July 24 2012."},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000033"},{"key":"e_1_2_5_6_1","unstructured":"National Down syndrome Society.What causes Down syndrome.2012. Available at:http:\/\/ndss.org\/index.php?option=com_content&view=article&id=60&Itemid=77. Accessed February 12 2012."},{"key":"e_1_2_5_7_1","first-page":"473","article-title":"Understanding the mechanism(s) of mosaic trisomy 21 by using DNA \u00adpolymorphism analysis","volume":"54","author":"Pangalos C","year":"1994","journal-title":"Am J Hum Genet"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2003.046219"},{"key":"e_1_2_5_9_1","unstructured":"Down Syndrome:a review for dental \u00adprofessionals: Southern Association of Institutional Dentists. Available at:http:\/\/saiddent.org\/admin\/images\/68542000_1339440469.pdf.Accessed March 15 2013."},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10519-010-9430-5"},{"key":"e_1_2_5_11_1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s00439-002-0871-7","article-title":"Patterns of associations of clinical features in neurofibromatosis 1 (NF1)","volume":"112","author":"Szudek J","year":"2003","journal-title":"Hum Genet"},{"key":"e_1_2_5_12_1","first-page":"590","volume-title":"Smith's recognizable patterns of human malformation,","author":"Jones K.","year":"2006"},{"key":"e_1_2_5_13_1","first-page":"2483","volume-title":"Nelson textbook of pediatrics","author":"Kliegman R","year":"2007"},{"key":"e_1_2_5_14_1","first-page":"105","volume-title":"Bates guide to \u00adphysicial examination and history taking,","author":"Bickley LS","year":"2003"},{"key":"e_1_2_5_15_1","first-page":"141","volume-title":"Burket's oral medicine: diagnosis and treatment","author":"Greenberg MS","year":"2003"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/79075"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-4-16"},{"key":"e_1_2_5_18_1","unstructured":"NEUROFIBROMATOSIS ATYPICAL.Online Mendielian Inheritance in Man; Available at:http:\/\/omim.org\/entry\/162270.Accessed June 1 2012."},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.20429"},{"key":"e_1_2_5_20_1","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1111\/j.1365-2230.1996.tb00084.x","article-title":"Triad of juvenile \u00adxanthogranuloma, von Recklinghausen's, neurofibromatosis and trisomy 21 in a young girl","volume":"21","author":"Van Leeuwen RL","year":"1996","journal-title":"Clin Exp Dermatol"},{"key":"e_1_2_5_21_1","unstructured":"MarionRobert.Personal communication June 2011."},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000179303.72345.ce"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3728-10.2010"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2788.2007.01038.x"}],"container-title":["Special Care in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fscd.12062","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/scd.12062","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T08:37:05Z","timestamp":1716280625000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/scd.12062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,10]]},"references-count":23,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.1111\/scd.12062"],"URL":"https:\/\/doi.org\/10.1111\/scd.12062","archive":["Portico"],"relation":{},"ISSN":["0275-1879","1754-4505"],"issn-type":[{"value":"0275-1879","type":"print"},{"value":"1754-4505","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,10]]}}}