{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T07:09:51Z","timestamp":1792393791246,"version":"4.4.0"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,7,15]],"date-time":"2014-07-15T00:00:00Z","timestamp":1405382400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Cowden syndrome or multiple hamartoma syndrome, is a rare genetic condition inherited in an autosomal dominant pattern characterized by cutaneous manifestations, polyps, thyroid gland neoplasias, and macrocephaly. This report presents the case of a 36\u2010year\u2010old patient who looked for dental treatment for a gingival nodule. Current and past medical history and oral and facial manifestations led to the diagnosis of Cowden syndrome. This case report emphasizes the role of the dental surgeon in the diagnosis of this systemic disease, based on the analysis of medical history and manifestations in the oral cavity.<\/jats:p>","DOI":"10.1111\/scd.12081","type":"journal-article","created":{"date-parts":[[2014,7,16]],"date-time":"2014-07-16T03:51:41Z","timestamp":1405482701000},"page":"51-54","source":"Crossref","is-referenced-by-count":10,"title":["Cowden syndrome\u2014a case report emphasizing the role of the dental surgeon in diagnosis"],"prefix":"10.1111","volume":"35","author":[{"given":"Liana Preto","family":"Webber","sequence":"first","affiliation":[{"name":"Master degree student, Department of Oral Pathology School of Dentistry Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoela Domingues","family":"Martins","sequence":"additional","affiliation":[{"name":"Assistant professor, Department of Oral Pathology, School of Dentistry Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vin\u00edcius Coelho","family":"Carrard","sequence":"additional","affiliation":[{"name":"Assistant professor, Department of Oral Pathology, School of Dentistry Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Ant\u00f4nio","family":"Trevizani Martins","sequence":"additional","affiliation":[{"name":"Assistant professor, Department of Oral Pathology, School of Dentistry Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Cristina","family":"Munerato","sequence":"additional","affiliation":[{"name":"Assistant professor, Department of Stomatology of Hospital de Cl\u00ednicas de Porto Alegre Universidade Federal do Rio Grande do Sul  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,7,15]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0596-114"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5200289"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0597-64"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2004.08.032"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12009"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2006.00896.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.37.11.828"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2011.05140.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9290.70803"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/0976-237X.111634"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2005.06.026"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1601-0825.2001.00679.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0103-64402006000100018"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2008.05.001"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2014.01.015"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e3181cfa7f0"},{"key":"e_1_2_5_18_1","first-page":"E421","article-title":"Oral manifestations of Cowden's disease. 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