{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T18:21:43Z","timestamp":1777314103073,"version":"3.51.4"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,4,5]],"date-time":"2016-04-05T00:00:00Z","timestamp":1459814400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Thrombocytopenia is the reduction in the number of blood \u00adplatelets, which may be caused by \u00adseveral different conditions such as sepsis, disseminated intravascular \u00adclotting, and large blood losses. Additionally, in rare situations, thrombocytopenia may also be induced by the use of medicaments. One of these drugs is the vancomycin, a glycopeptide presently used against \u00adserious infections involving Gram\u2010positive bacteria such as the methicillin\u2010resistant <jats:italic>Staphylococcus aureus<\/jats:italic> and penicillin\u2010resistant <jats:italic>Streptococcus<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The objective of this study is to report on a case of serious vancomycin\u2010induced thrombocytopenia in a patient infected with methicillin\u2010resistant <jats:italic>S. aureus<\/jats:italic> after mandibular reconstruction with autogenous bone graft, and to draw attention to the importance of this clinically rare adverse effect.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Vancomycin\u2010induced thrombocytopenia is a rare condition, which is also a significant disorder that demands attention and the rapid identification and replacement of the antimicrobial agent.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.12182","type":"journal-article","created":{"date-parts":[[2016,4,10]],"date-time":"2016-04-10T12:33:38Z","timestamp":1460291618000},"page":"38-42","source":"Crossref","is-referenced-by-count":6,"title":["Vancomycin\u2010induced thrombocytopenia: a rare adverse effect in a patient \u00adsubmitted to bone graft in the jaw"],"prefix":"10.1111","volume":"37","author":[{"given":"Carolina Ferrairo","family":"Danieletto","sequence":"first","affiliation":[{"name":"Master Student, Implantodonty, Ara\u00e7atuba Dentistry School UNESP \u2013 Universidade Estadual Paulista  Ara\u00e7atuba S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo Zanna","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Professor, Dental Surgery, Department of Dentistry UNICESUMAR \u2013 Cesumar University Center  Maring\u00e1 Paran\u00e1 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