{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T18:22:12Z","timestamp":1763058132799},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,2,8]],"date-time":"2018-02-08T00:00:00Z","timestamp":1518048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Langerhans cell histiocytosis (LCH) is a childhood pathology with a peak of incidence ranging from 1 to 4 years of age, though diagnosis is often made in adult age. LCH is clinically classified into three types: eosinophilic granuloma, Hand\u2013Schuller\u2013Christian disease and Abt\u2013Letterer\u2013Siwe disease. We report a case of Hand\u2013Sch\u00fcller\u2013Christian disease with diabetes insipidus, skull and maxillary involvement in a 16\u2010year\u2010old boy referred to our observation for gradual increase in mobility of the teeth and subsequent gradual loss of the second premolars and the first molars of the upper jaw. Due to the extension of the lesion and the age of the patient, surgery, and chemotherapy was chosen as the more fit treatment according to the current protocol. The clinical and radiological evaluation at the end of the therapy and after 5 years showed complete remission. The absence of relapse has allowed to initiate a fixed orthodontic dental alignment treatment with a good response to orthodontic treatment despite the underlying disease. The present case exemplifies the importance of close multidisciplinary dental and medical collaboration including general dentistry, periodontology, oral medicine, oral and maxillofacial pathology, oral radiology, orthodontics\u00a0and hematology\u2010oncology for diagnosis, management, treatment monitoring, and decision\u2010making.<\/jats:p>","DOI":"10.1111\/scd.12273","type":"journal-article","created":{"date-parts":[[2018,2,8]],"date-time":"2018-02-08T10:42:57Z","timestamp":1518086577000},"page":"107-111","source":"Crossref","is-referenced-by-count":5,"title":["Multidisciplinary approach in a case of Hand\u2013Sch\u00fcller\u2013Christian disease with maxillary involvement"],"prefix":"10.1111","volume":"38","author":[{"given":"Angela Pia","family":"Cazzolla","sequence":"first","affiliation":[{"name":"Clinic of Dentistry University of Bari  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nunzio Francesco","family":"Testa","sequence":"additional","affiliation":[{"name":"Clinic of Dentistry University of Bari  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianfranco","family":"Favia","sequence":"additional","affiliation":[{"name":"Clinic of Dentistry University of Bari  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Grazia","family":"Lacaita","sequence":"additional","affiliation":[{"name":"Clinic of Dentistry University of Bari  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Ciavarella","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Foggia  Foggia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khrystyna","family":"Zhurakivska","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Foggia  Foggia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Troiano","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Foggia  Foggia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenzo","family":"Lo Muzio","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Foggia  Foggia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,2,8]]},"reference":[{"issue":"8526","key":"e_1_2_10_2_1","first-page":"208","article-title":"Writing Group of the Histiocyte Society","volume":"1","author":"Histiocytosis syndromes in children","year":"1987","journal-title":"Lancet"},{"issue":"1","key":"e_1_2_10_3_1","first-page":"79","article-title":"Langerhans cell histiocytosis: a 16\u2010year experience","volume":"83","author":"Campos MK","year":"2007","journal-title":"J Pediatr (Rio J)"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-911X(199709)29:3<157::AID-MPO1>3.0.CO;2-C"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19990515)85:10<2278::AID-CNCR25>3.0.CO;2-U"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2002.73.12.1528"},{"key":"e_1_2_10_7_1","first-page":"67","article-title":"Carpentieri, and John P. 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