{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T08:33:49Z","timestamp":1778142829389,"version":"3.51.4"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T00:00:00Z","timestamp":1520294400000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Special Care in Dentistry"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To report a case of a pediatric patient carrier of myelodysplastic syndrome (MDS) with severe oral infectious disease, in which antimicrobial photodynamic therapy (aPDT) was used as a therapeutic choice to support systemic treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>This case report refers to a 1\u2010year\u2010old male patient with MDS and hospitalized for investigation and treatment of complications at a Pediatric Oncology and Hematology Center in Recife\/PE, Brazil. The intraoral examination revealed a violaceous lesion surrounding the lower incisor teeth, which progressed with alteration of color to milky yellowish white, compromising the entire lower gingival border, leading to tooth mobility and consequent loss of teeth 71 and 81. The patient was treated under systemic antimicrobial therapy and aPDT was also performed, using a photosensitizing agent (methylene blue, 0.01%) and a low\u2010intensity laser in the visible red spectrum. Oral clinical improvement was observed, but the patient died after 45 days of hospitalization in the Pediatric ICU due to other systemic complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MDS may present limiting oral repercussions interfering in patients\u2019 quality of life. The aPDT is presented as an adjuvant therapeutic modality in oral infections with satisfactory results.<\/jats:p><\/jats:sec>","DOI":"10.1111\/scd.12275","type":"journal-article","created":{"date-parts":[[2018,3,6]],"date-time":"2018-03-06T16:52:49Z","timestamp":1520355169000},"page":"95-98","source":"Crossref","is-referenced-by-count":5,"title":["The use of antimicrobial photodynamic therapy in oral injuries of a pediatric patient with myelodysplastic syndrome: case report"],"prefix":"10.1111","volume":"38","author":[{"given":"Maria Cec\u00edlia Freire","family":"de Melo","sequence":"first","affiliation":[{"name":"Resident Dentist, Residency Program in Hospital Dentistry Focusing on Oncology, University of Pernambuco, ICB\/HUOC\/UPE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thuanny","family":"Silva de Macedo","sequence":"additional","affiliation":[{"name":"Resident Dentist, Residency Program in Hospital Dentistry Focusing on Oncology, University of Pernambuco, ICB\/HUOC\/UPE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julianelly Alves","family":"Biserra","sequence":"additional","affiliation":[{"name":"Resident Dentist, Residency Program in Palliative Care, University of Pernambuco, ICB\/HUOC\/UPE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karina Luz Cavalcanti","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Specialist in Pediatric Oncology, Pediatric Oncology and Hematology Center, Oswaldo Cruz University Hospital, CEONPE\/HUOC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00f4nica","family":"Cruz","sequence":"additional","affiliation":[{"name":"Dentist, Pediatric Oncology and Hematology Center of the Oswaldo Cruz University Hospital, CEONPE\/HUOC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurora Karla de Lacerda","family":"Vidal","sequence":"additional","affiliation":[{"name":"Resident Dentist, Residency Program in Hospital Dentistry Focusing on Oncology, University of Pernambuco, ICB\/HUOC\/UPE"},{"name":"Profa. Dra. Adjunct Regent, General Pathological Processes Discipline, ICB\/UPE Chief Dentist, Dentistry Service, CEON\/HUOC\/UPE, and Coordinator, Residency Program in Hospital Dentistry Focusing on Oncology, University of Pernambuco, ICB\/HUOC\/UPE"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,6]]},"reference":[{"issue":"9","key":"e_1_2_7_2_1","first-page":"831","article-title":"Myelodysplasic syndromes: 2018 update on diagnosis, risk\u2010stratification and management","volume":"90","author":"Montalban\u2010Bravo G","year":"2018","journal-title":"Am J Hematol"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12185-016-1965-7"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-016-2649-3"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-84842006000300016"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2012.063420"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3343\/alm.2017.37.6.465"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.21080"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-017-2133-y"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/1574-6976.12026"},{"issue":"1","key":"e_1_2_7_11_1","first-page":"80","article-title":"S\u00edndrome mielodispl\u00e1sica: da suspeita ao diagn\u00f3stico definitivo. 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